Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

Journal of Experimental Medicine

Volumn 171, Issue 1, 1990, Pages 265-297

  Shlomchik, M ^a   Mascelli, M ^a   Shan, H ^a   Radic, M Z ^a   Pisetsky, D ^a   Marshak Rothstein, A ^a   Weigert, M ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA ANTIBODY; IMMUNOGLOBULIN IDIOTYPE;

ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNITY; GENETIC ENGINEERING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOMATIC MUTATION; SYSTEMIC LUPUS ERYTHEMATOSUS;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; AUTOANTIBODIES; AUTOIMMUNE DISEASES; BASE SEQUENCE; CLONE CELLS; COMPARATIVE STUDY; DNA; DNA, SINGLE-STRANDED; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENES, IMMUNOGLOBULIN; IMMUNOGLOBULIN JOINING REGION; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOGLOBULINS, HEAVY-CHAIN; IMMUNOGLOBULINS, KAPPA-CHAIN; MICE; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDE PROBES; RNA, MESSENGER; SPECIES SPECIFICITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025017688     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.171.1.265     Document Type: Article

References (0)