메뉴 건너뛰기




Volumn 101, Issue 3, 1990, Pages 746-752

Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ARGININE; BRADYKININ; CYCLIC GMP; INDOMETACIN; METHYLARGININE; N5 (1 IMINOETHYL)ORNITHINE; NITRIC OXIDE; NITROARGININE METHYL ESTER; PHENYLEPHRINE; RADIOISOTOPE; SYNTHETASE; UNCLASSIFIED DRUG;

EID: 0025011716     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1990.tb14151.x     Document Type: Article
Times cited : (1860)

References (36)
  • 1
    • 0024475102 scopus 로고
    • NG‐methylarginine, an inhibitor of endothelium‐derived nitric oxide synthesis, is a potent pressor agent in the guinea‐pig: does nitric oxide regulate blood pressure in vivo?
    • AISAKA, K., GROSS, S.S., GRIFFITH, O.W. & LEVI, R. (1989a). N G ‐methylarginine, an inhibitor of endothelium‐derived nitric oxide synthesis, is a potent pressor agent in the guinea‐pig: does nitric oxide regulate blood pressure in vivo? Biochem. Biophys. Res. Commun., 160, 881–886.
    • (1989) Biochem. Biophys. Res. Commun , vol.160 , pp. 881-886
    • AISAKA, K.1    GROSS, S.S.2    GRIFFITH, O.W.3    LEVI, R.4
  • 2
    • 0024440973 scopus 로고
    • l‐arginine availability determines the duration of acetylcholine‐induced systemic vasodilation in vivo
    • AISAKA, K., GROSS, S.S., GRIFFITH, O.W. & LEVI, R. (1989b). l‐arginine availability determines the duration of acetylcholine‐induced systemic vasodilation in vivo. Biochem. Biophys. Res. Commun., 163, 710–717.
    • (1989) Biochem. Biophys. Res. Commun , vol.163 , pp. 710-717
    • AISAKA, K.1    GROSS, S.S.2    GRIFFITH, O.W.3    LEVI, R.4
  • 3
    • 0023686224 scopus 로고
    • Acetylcholine induces vasodilatation in the rabbit isolated heart through the release of nitric oxide, the endogenous nitrovasodilator
    • AMEZCUA, J.L., DUSTING, G.J., PALMER, R.M.J. & MONCADA, S. (1988). Acetylcholine induces vasodilatation in the rabbit isolated heart through the release of nitric oxide, the endogenous nitrovasodilator. Br. J. Pharmacol., 95, 830–834.
    • (1988) Br. J. Pharmacol , vol.95 , pp. 830-834
    • AMEZCUA, J.L.1    DUSTING, G.J.2    PALMER, R.M.J.3    MONCADA, S.4
  • 4
    • 0024819580 scopus 로고
    • Nitric oxide synthesized from l‐arginine regulates vascular tone in the coronary circulation of the rabbit
    • AMEZCUA, J.L., PALMER, R.M.J., de SOUZA, B.M. & MONCADA, S. (1989). Nitric oxide synthesized from l‐arginine regulates vascular tone in the coronary circulation of the rabbit. Br. J. Pharmacol., 97, 1119–1124.
    • (1989) Br. J. Pharmacol , vol.97 , pp. 1119-1124
    • AMEZCUA, J.L.1    PALMER, R.M.J.2    de SOUZA, B.M.3    MONCADA, S.4
  • 6
    • 0003987444 scopus 로고
    • Endothelium‐derived relaxing factor: some old and new findings, in: Nitric Oxide from l‐Arginine: a Bioregulatory System
    • FURCHGOTT, R.F. (1990). Endothelium‐derived relaxing factor: some old and new findings. In Nitric Oxide from l‐Arginine: a Bioregulatory System ed. Moncada, S. & Higgs, E.A. pp. 5–17. Amsterdam: Elsevier.
    • (1990) , pp. 5-17
    • FURCHGOTT, R.F.1
  • 7
    • 0024462440 scopus 로고
    • NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices
    • GARTHWAITE, J., GARTHWAITE, G., PALMER, R.M.J. & MONCADA, S. (1989). NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. Eur. J. Pharmacol., 172, 413–416.
    • (1989) Eur. J. Pharmacol , vol.172 , pp. 413-416
    • GARTHWAITE, J.1    GARTHWAITE, G.2    PALMER, R.M.J.3    MONCADA, S.4
  • 8
    • 0025195320 scopus 로고
    • l‐NG‐monomethylarginine and l‐NG‐nitroarginine inhibit non‐adrenergic, non‐cholinergic relaxation of the mouse anococcygeus muscle
    • GIBSON, A., SHOKOUFEH, M., HOBBS, A.J. & MOORE, P.K. (1990). l‐N G ‐monomethylarginine and l‐N G ‐nitroarginine inhibit non‐adrenergic, non‐cholinergic relaxation of the mouse anococcygeus muscle. Br. J. Pharmacol., 99, 602–606.
    • (1990) Br. J. Pharmacol , vol.99 , pp. 602-606
    • GIBSON, A.1    SHOKOUFEH, M.2    HOBBS, A.J.3    MOORE, P.K.4
  • 9
    • 0038102563 scopus 로고
    • Agonist‐ and tissue‐dependence of susceptibility of endothelium‐dependent relaxations to l‐NAME.
    • GILES, H., BOLOFO, M.L. & MARTIN, G.R. (1990). Agonist‐ and tissue‐dependence of susceptibility of endothelium‐dependent relaxations to l‐NAME. Br. J. Pharmacol., 100, 452P.
    • (1990) Br. J. Pharmacol , vol.100 , pp. 452P
    • GILES, H.1    BOLOFO, M.L.2    MARTIN, G.R.3
  • 10
    • 0024836368 scopus 로고
    • The effects of l‐arginine and NG‐monomethyl l‐arginine on the response of the rat anococcygeus muscle to NANC nerve stimulation
    • GILLESPIE, J.S., LIU, X. & MARTIN, W. (1989). The effects of l‐arginine and N G ‐monomethyl l‐arginine on the response of the rat anococcygeus muscle to NANC nerve stimulation. Br. J. Pharmacol., 98, 1080–1082.
    • (1989) Br. J. Pharmacol , vol.98 , pp. 1080-1082
    • GILLESPIE, J.S.1    LIU, X.2    MARTIN, W.3
  • 11
    • 0023505509 scopus 로고
    • Endothelium‐derived relaxing factor produced and released from artery and vein is nitric oxide
    • IGNARRO, L.J., BUGA, G.M., WOOD, K.S., BYRNS, R.E. & CHAUDHURI, G. (1987). Endothelium‐derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Natl. Acad. Sci., U.S.A., 84, 9265–9269.
    • (1987) Proc. Natl. Acad. Sci., U.S.A. , vol.84 , pp. 9265-9269
    • IGNARRO, L.J.1    BUGA, G.M.2    WOOD, K.S.3    BYRNS, R.E.4    CHAUDHURI, G.5
  • 12
    • 0023715311 scopus 로고
    • Nitric oxide release from the isolated guinea pig heart
    • KELM, M. & SCHRADER, J. (1988). Nitric oxide release from the isolated guinea pig heart. Eur. J. Pharmacol., 155, 313–316.
    • (1988) Eur. J. Pharmacol , vol.155 , pp. 313-316
    • KELM, M.1    SCHRADER, J.2
  • 13
    • 0343046540 scopus 로고
    • Formation of nitric oxide from l‐arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase
    • KNOWLES, R.G., PALACIOS, M., PALMER, R.M.J. & MONCADA, S. (1989). Formation of nitric oxide from l‐arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase. Proc. Natl. Acad. Sci., U.S.A., 86, 5159–5162.
    • (1989) Proc. Natl. Acad. Sci., U.S.A. , vol.86 , pp. 5159-5162
    • KNOWLES, R.G.1    PALACIOS, M.2    PALMER, R.M.J.3    MONCADA, S.4
  • 14
    • 0025351885 scopus 로고
    • Kinetic characteristics of nitric oxide synthase from rat brain
    • KNOWLES, R.G., PALACIOS, M., PALMER, R.M.J. & MONCADA, S. (1990). Kinetic characteristics of nitric oxide synthase from rat brain. Biochem. J., 269, 207–210.
    • (1990) Biochem. J. , vol.269 , pp. 207-210
    • KNOWLES, R.G.1    PALACIOS, M.2    PALMER, R.M.J.3    MONCADA, S.4
  • 15
    • 0025096777 scopus 로고
    • Nitroarginine inhibits endothelium‐derived relaxation
    • KOBAYASHI, Y. & HATTORI, K. (1990). Nitroarginine inhibits endothelium‐derived relaxation. Jpn. J. Pharmacol., 52, 167–169.
    • (1990) Jpn. J. Pharmacol , vol.52 , pp. 167-169
    • KOBAYASHI, Y.1    HATTORI, K.2
  • 16
    • 0024986462 scopus 로고
    • Evidence that l‐arginine is the biosynthetic precursor of vascular and cardiac nitric oxide, in: Nitric Oxide from l‐Arginine: a Bioregulatory System
    • LEVI, R., GROSS, S.S., LAMPARTER, B., FASEHUN, O.A., AISAKA, K., JAFFE, E.A., GRIFFITH, O.W. & STUEHR, D.J. (1990). Evidence that l‐arginine is the biosynthetic precursor of vascular and cardiac nitric oxide. In Nitric Oxide from l‐Arginine: a Bioregulatory System. ed. Moncada, S. & Higgs, E.A. pp. 35–45. Amsterdam: Elsevier.
    • (1990) , pp. 35-45
    • LEVI, R.1    GROSS, S.S.2    LAMPARTER, B.3    FASEHUN, O.A.4    AISAKA, K.5    JAFFE, E.A.6    GRIFFITH, O.W.7    STUEHR, D.J.8
  • 17
    • 0024989520 scopus 로고
    • The l‐arginine:nitric oxide pathway in neutrophils, in: Nitric Oxide from l‐Arginine: a Bioregulatory System
    • McCALL, T. PALMER, R.M.J., BOUGHTON‐SMITH, N., WHITTLE, B.J.R. & MONCADA, S. (1990). The l‐arginine:nitric oxide pathway in neutrophils. In Nitric Oxide from l‐Arginine: a Bioregulatory System. ed. Moncada, S. & Higgs, E.A. pp. 257–265. Amsterdam: Elsevier.
    • (1990) , pp. 257-265
    • McCALL, T.1    PALMER, R.M.J.2    BOUGHTON‐SMITH, N.3    WHITTLE, B.J.R.4    MONCADA, S.5
  • 18
    • 0024427710 scopus 로고
    • Biosynthesis of endothelium‐derived relaxing factor, a cytosolic enzyme in porcine aortic endothelial cells Ca2+‐dependently converts l‐arginine into an activator of guanylate cyclase
    • MEYER, B., SCHMIDT, K., HUMBERT, R. & BOHME, E. (1989). Biosynthesis of endothelium‐derived relaxing factor, a cytosolic enzyme in porcine aortic endothelial cells Ca 2+ ‐dependently converts l‐arginine into an activator of guanylate cyclase. Biochem. Biophys. Res. Commun., 164, 678–685.
    • (1989) Biochem. Biophys. Res. Commun , vol.164 , pp. 678-685
    • MEYER, B.1    SCHMIDT, K.2    HUMBERT, R.3    BOHME, E.4
  • 19
    • 0025194144 scopus 로고
    • l‐NG‐nitro arginine (l‐NOARG) a novel, l‐arginine‐reversible inhibitor of endothelium‐dependent vasodilatation in vitro
    • MOORE, P.K., AL‐SWAYEH, O.A., CHONG, N.W.S., EVANS, R.A. & GIBSON, A. (1990). l‐N G ‐nitro arginine (l‐NOARG) a novel, l‐arginine‐reversible inhibitor of endothelium‐dependent vasodilatation in vitro. Br. J. Pharmacol., 99, 408–412.
    • (1990) Br. J. Pharmacol , vol.99 , pp. 408-412
    • MOORE, P.K.1    AL‐SWAYEH, O.A.2    CHONG, N.W.S.3    EVANS, R.A.4    GIBSON, A.5
  • 20
    • 0024851677 scopus 로고
    • Nitric oxide synthesis in endothelial cytosol: Evidence for a calcium‐dependent and a calcium‐independent mechanism
    • MÜLSCH, A., BASSENGE, E. & BUSSE, R. (1989). Nitric oxide synthesis in endothelial cytosol: Evidence for a calcium‐dependent and a calcium‐independent mechanism. Naunyn-Schmiedebergs Arch. Pharmacol., 340, 767–770.
    • (1989) Naunyn-Schmiedebergs Arch. Pharmacol , vol.340 , pp. 767-770
    • MÜLSCH, A.1    BASSENGE, E.2    BUSSE, R.3
  • 21
    • 0025194259 scopus 로고
    • NG‐nitro‐l‐arginine (N5‐[imino(nitro amino)methyl]‐l‐ornithine) impairs endothelium‐dependent dilations by inhibiting cytosolic nitric oxide synthesis from l‐arginine
    • MÜLSCH, A. & BUSSE, R. (1990). N G ‐nitro‐l‐arginine (N 5 ‐[imino(nitro amino)methyl]‐l‐ornithine) impairs endothelium‐dependent dilations by inhibiting cytosolic nitric oxide synthesis from l‐arginine. Naunyn-Schmiedebergs Arch. Pharmacol., 341, 143–147.
    • (1990) Naunyn-Schmiedebergs Arch. Pharmacol , vol.341 , pp. 143-147
    • MÜLSCH, A.1    BUSSE, R.2
  • 22
    • 0024833507 scopus 로고
    • Nitric oxide from l‐arginine stimulates the soluble guanylate cyclase in adrenal glands
    • PALACIOS, M., KNOWLES, R.G., PALMER, R.M.J. & MONCADA, S. (1989). Nitric oxide from l‐arginine stimulates the soluble guanylate cyclase in adrenal glands. Biochem. Biophys. Res. Commun., 165, 802–809.
    • (1989) Biochem. Biophys. Res. Commun , vol.165 , pp. 802-809
    • PALACIOS, M.1    KNOWLES, R.G.2    PALMER, R.M.J.3    MONCADA, S.4
  • 23
    • 0024491211 scopus 로고
    • A novel citrulline‐forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells
    • PALMER, R.M.J. & MONCADA, S. (1989). A novel citrulline‐forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells. Biochem. Biophys. Res. Commun., 158, 348–352.
    • (1989) Biochem. Biophys. Res. Commun , vol.158 , pp. 348-352
    • PALMER, R.M.J.1    MONCADA, S.2
  • 24
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium‐derived relaxing factor
    • PALMER, R.M.J., FERRIGE, A.G. & MONCADA, S. (1987). Nitric oxide release accounts for the biological activity of endothelium‐derived relaxing factor. Nature, 327, 524–526.
    • (1987) Nature , vol.327 , pp. 524-526
    • PALMER, R.M.J.1    FERRIGE, A.G.2    MONCADA, S.3
  • 25
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from l‐arginine
    • PALMER, R.M.J., ASHTON, D.S. & MONCADA, S. (1988a). Vascular endothelial cells synthesize nitric oxide from l‐arginine. Nature, 333, 664–666.
    • (1988) Nature , vol.333 , pp. 664-666
    • PALMER, R.M.J.1    ASHTON, D.S.2    MONCADA, S.3
  • 26
    • 0024300153 scopus 로고
    • l‐arginine is the physiological precursor for the formation of nitric oxide in endothelium‐dependent relaxation
    • PALMER, R.M.J., REES, D.D., ASHTON, D.S. & MONCADA, S. (1988b). l‐arginine is the physiological precursor for the formation of nitric oxide in endothelium‐dependent relaxation. Biochem. Biophys. Res. Commun., 153, 1251–1256.
    • (1988) Biochem. Biophys. Res. Commun , vol.153 , pp. 1251-1256
    • PALMER, R.M.J.1    REES, D.D.2    ASHTON, D.S.3    MONCADA, S.4
  • 27
    • 0017624736 scopus 로고
    • Preparation and characterisation of NG‐mono‐di‐ and trimethylated arginines
    • PATTHY, A., BAJUSZ, S. & PATTHY, L. (1977). Preparation and characterisation of N G ‐mono‐di‐ and trimethylated arginines. Acta. Biochim. Biophys. Acad. Sci. Hung., 12, 191–196.
    • (1977) Acta. Biochim. Biophys. Acad. Sci. Hung , vol.12 , pp. 191-196
    • PATTHY, A.1    BAJUSZ, S.2    PATTHY, L.3
  • 28
    • 0023187143 scopus 로고
    • Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets
    • RADOMSKI, M.W., PALMER, R.M.J. & MONCADA, S. (1987a). Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets. Br. J. Pharmacol., 92, 181–187.
    • (1987) Br. J. Pharmacol , vol.92 , pp. 181-187
    • RADOMSKI, M.W.1    PALMER, R.M.J.2    MONCADA, S.3
  • 29
    • 0023446425 scopus 로고
    • The antiaggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide
    • RADOMSKI, M.W., PALMER, R.M.J. & MONCADA, S. (1987b). The antiaggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide. Br. J. Pharmacol., 92, 639–646.
    • (1987) Br. J. Pharmacol , vol.92 , pp. 639-646
    • RADOMSKI, M.W.1    PALMER, R.M.J.2    MONCADA, S.3
  • 30
    • 0025131570 scopus 로고
    • Characterisation of the l‐arginine:nitric oxide pathway in human platelets
    • RADOMSKI, M.W., PALMER, R.M.J. & MONCADA, S. (1990). Characterisation of the l‐arginine:nitric oxide pathway in human platelets. Br. J. Pharmacol. (in press).
    • (1990) Br. J. Pharmacol
    • RADOMSKI, M.W.1    PALMER, R.M.J.2    MONCADA, S.3
  • 31
    • 0024528921 scopus 로고
    • A specific inhibitor of nitric oxide formation from l‐arginine attenuates endothelium‐dependent relaxation
    • REES, D.D., PALMER, R.M.J., HODSON, H.F. & MONCADA, S. (1989a). A specific inhibitor of nitric oxide formation from l‐arginine attenuates endothelium‐dependent relaxation. Br. J. Pharmacol., 96, 418–424.
    • (1989) Br. J. Pharmacol , vol.96 , pp. 418-424
    • REES, D.D.1    PALMER, R.M.J.2    HODSON, H.F.3    MONCADA, S.4
  • 32
    • 0001599370 scopus 로고
    • Role of endothelium‐derived nitric oxide in the regulation of blood pressure
    • REES, D.D., PALMER, R.M.J. & MONCADA, S. (1989b). Role of endothelium‐derived nitric oxide in the regulation of blood pressure. Proc. Natl. Acad. Sci. U.S.A., 86, 3375–3378.
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 3375-3378
    • REES, D.D.1    PALMER, R.M.J.2    MONCADA, S.3
  • 33
    • 0024259715 scopus 로고
    • Identification of arginine as a precursor of endothelium‐derived relaxing factor (EDRF)
    • SAKUMA, I., STUEHR, D.J., GROSS, S.S., NATHAN, C. & LEVI, R. (1988). Identification of arginine as a precursor of endothelium‐derived relaxing factor (EDRF). Proc. Natl. Acad. Sci., U.S.A., 85, 8664–8667.
    • (1988) Proc. Natl. Acad. Sci., U.S.A. , vol.85 , pp. 8664-8667
    • SAKUMA, I.1    STUEHR, D.J.2    GROSS, S.S.3    NATHAN, C.4    LEVI, R.5
  • 34
    • 0015311896 scopus 로고
    • Antimetabolites produced by microorganisms. VI. L‐N‐(1‐iminoethyl) ornithine
    • SCANNELL, J.P., AX, H.A., PRUESS, D.L., WILLIAMS, T., DEMNY, T.C. & STEMPEL, A. (1972). Antimetabolites produced by microorganisms. VI. L‐N‐(1‐iminoethyl) ornithine. J. Antibiot., 25, 179–184.
    • (1972) J. Antibiot , vol.25 , pp. 179-184
    • SCANNELL, J.P.1    AX, H.A.2    PRUESS, D.L.3    WILLIAMS, T.4    DEMNY, T.C.5    STEMPEL, A.6
  • 35
    • 0024428094 scopus 로고
    • Effects of endothelium‐derived nitric oxide on peripheral arteriolar tone in man
    • VALLANCE, P., COLLIER, J. & MONCADA, S. (1989a). Effects of endothelium‐derived nitric oxide on peripheral arteriolar tone in man. Lancet, ii, 997–1000.
    • (1989) Lancet , vol.ii , pp. 997-1000
    • VALLANCE, P.1    COLLIER, J.2    MONCADA, S.3
  • 36
    • 85047678425 scopus 로고
    • Nitric oxide synthesised from l‐arginine mediates endothelium‐dependent dilatation in human veins
    • VALLANCE, P., COLLIER, J. & MONCADA, S. (1989b). Nitric oxide synthesised from l‐arginine mediates endothelium‐dependent dilatation in human veins. Cardiovasc. Res., 23, 1053–1057.
    • (1989) Cardiovasc. Res , vol.23 , pp. 1053-1057
    • VALLANCE, P.1    COLLIER, J.2    MONCADA, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.