1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

Biochemical and Biophysical Research Communications

Volumn 170, Issue 3, 1990, Pages 1049-1055

  Hasegawa, Eiji ^a   Takeshige, Koichiro ^b   Oishi, Tomonari ^a   Murai, Yoshiyuki ^a   Minakami, Shigeki ^b  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; SUPEROXIDE;

ANIMAL CELL; ARTICLE; CATTLE; HEART MITOCHONDRION; LIPID PEROXIDATION; NONHUMAN; PRIORITY JOURNAL;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMAL; CATTLE; FREE RADICALS; LIPID PEROXIDATION; MITOCHONDRIA, HEART; NAD; SUBMITOCHONDRIAL PARTICLES; SUPEROXIDES; SUPPORT, NON-U.S. GOV'T;

ANIMALIA; BOS TAURUS; BOVINAE; PARKINSONIA;

EID: 0024997609     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/0006-291X(90)90498-C     Document Type: Article

References (33)

1. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) cause rapid ATP depletion in isolated hepatocytes
2. Model study on the bioreduction of paraquat, MPP+, and analogs. Evidence against a “redox cycling” mechanism in MPTP neurotoxicity
3. Free Radical Biology and Medicine