Preclinical and clinical evaluation of recombinant human macrophage colony‐stimulating factor (rhM‐CSF)

The International Journal of Cell Cloning

Volumn 8, Issue 1 S, 1990, Pages 356-373

  Garnick, Marc B ^a,b   Stoudemire, John B ^a  

^a PFIZER INC   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Hematopoietic growth factors; Recombinant human macrophage colony stimulating factor

Indexed keywords

COLONY STIMULATING FACTOR 1;

CONFERENCE PAPER; GENETIC ENGINEERING; HEMATOPOIESIS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMAL; COLONY-STIMULATING FACTORS; HUMAN; IN VITRO; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; RECOMBINANT PROTEINS;

EID: 0024986524     PISSN: 07371454     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.5530080733     Document Type: Article

References (43)

1. Human GM‐CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins
2. Recombinant human granulocyte‐colony stimulating factor: effects on normal and leukemic myeloid cells
3. Human IL‐3 (multi‐CSF): identification by expression cloning of a novel hemopoietic growth factor related to murine IL‐3
4. Human CSF‐1: molecular cloning and expression of 4‐kb cDNA encoding the human urinary protein
5. The clinical promise of recombinant human macrophage colony stimulating factor (rhM‐CSF)
6. Survival of mononuclear phagocytes depends on a lineage‐specific growth factor that the differentiated cells selectively destroy
7. The granulocyte‐macrophage colony‐stimulating factors
8. Expression of the M‐CSF (CSF‐1) gene by human monocytes
9. Regulation of colony stimulating activity production: interactions of fibroblasts, mononuclear phagocytes, and lactoferrin
10. Increased serum concentrations of colony stimulating factor‐1 in myeloproliferative disease
11. Molecular cloning of a complementary DNA encoding human macrophage‐specific colony‐stimulating factor (CSF‐1)
12. Colony stimulating factor induced monocyte survival and differentiation into macrophages in serum free cultures
13. Survival of mononuclear phagocytes depends on a lineage‐specific growth factor that the differentiated cells selectively destroy
14. Effect of colony stimulating factor on murine macrophages. Induction of anti‐tumor activity
15. Stimulation of macrophage tumoricidal activity by the growth and differentiation factor CSF‐1
16. Biological properties and molecular biology of the human macrophage growth factor CSF‐1
17. Analysis of Ia antigen expression in macrophage‐colony stimulating factor
18. Differential effect of recombinant granulocyte macrophage colony‐stimulating factor on human monocytes and alveolar macrophages
19. Recombinant macrophage‐colony stimulating factor (M‐CSF) includes high levels of anti‐tumor antibody‐dependent cellular cytotoxicity (ADCC) by cultured human monocytes
20. Antibody‐dependent antitumor cytotoxicity by human monocytes cultured with recombinant macrophage colony stimulating factor
21. Macrophage colony‐stimulating factor enhances monocyte and macrophage antibody‐dependent cell‐mediated cytotoxicity
22. Effects of parenteral macrophage‐colony stimulating factor (M‐CSF) on circulating monocyte number, immunophenotype and anti‐tumor activity in cynomolgus monkeys
23. Growth response of human myeloid leukemia cells to colony stimulating factors
24. Effect of recombinant human M‐CSF on the proliferation of leukemic blast progenitors in AML patients
25. The effects of recombinant CSF‐1 on the blast cells of acute myeloblastic leukemia in suspension culture
26. The effects of combinations of the recombinant growth factors GM‐CSF, G‐CSF, IL‐3 and CSF‐1
27. In vivo effects of recombinant human macrophage‐colony stimulating factor (rhM‐CSF) in primates
28. In vitro and in vivo biological effects of recombinant human macrophage‐colony stimulating factor (rhM‐CSF)
29. Marked serum cholesterol (C) and low density lipoprotein C (LDLC) lowering activity induced by recombinant human macrophage‐colony stimulating factor (rhM‐CSF) and other hematopoietic growth factors (HGF) in primates
30. Macrophages specifically regulate the concentration of their own growth factor in the circulation
31. Pharmacokinetics of recombinant human macrophage‐colony stimulating factor (rhM‐CSF) in primates and rodents
32. Increases in neutrophil counts by purified human urinary colony‐stimulating factor in chronic neutropenia of childhood
33. Administration of human urinary colony stimulating factor after bone marrow transplantation
34. Purification, gene cloning, and clinical application of human monocyte specific colony‐stimulating factor
35. Clinical application of partially purified human urinary colony‐stimulating factor
36. Recombinant human monocyte specific colony‐stimulating factor stimulates both immature and mature cells of the human monocyte lineage
37. Phase I trial of recombinant macrophage colony stimulating factor (rhM‐CSF) in patients (PTS) with melanoma (MEL)
38. Effects of recombinant human macrophage colony stimulating factor (rHuM‐CSF) on hematopoiesis following high‐dose chemotherapy (HDC) and autologous bone marrow support (ABMS)