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Volumn 321, Issue 25, 1989, Pages 1725-1738

Cyclosporine

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; CYCLOSPORIN DERIVATIVE;

EID: 0024976004     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198912213212507     Document Type: Review
Times cited : (1647)

References (101)
  • 1
    • 0023916766 scopus 로고
    • Cyclosporine: conformation and analogues as tools for studying its mechanism of action
    • Wenger RM. Cyclosporine: conformation and analogues as tools for studying its mechanism of action. Transplant Proc 1988; 20: Suppl 2: 313–8.
    • (1988) Transplant Proc , vol.20 , pp. 313-318
    • Wenger, R.M.1
  • 2
    • 0022385998 scopus 로고
    • Individualization of cyclosporine therapy using pharmacokinetic and pharmacodynamic parameters
    • Kahan BD. Individualization of cyclosporine therapy using pharmacokinetic and pharmacodynamic parameters. Transplantation 1985; 40: 457–76.
    • (1985) Transplantation , vol.40 , pp. 457-476
    • Kahan, B.D.1
  • 3
    • 84944283396 scopus 로고
    • Cyclosporine improves psoriasis in a double-blind study
    • Ellis CN, Gorsulowsky DC, Hamilton TA, et al. Cyclosporine improves psoriasis in a double-blind study. JAMA 1986; 256: 3110–6.
    • (1986) JAMA , vol.256 , pp. 3110-3116
    • Ellis, C.N.1    Gorsulowsky, D.C.2    Hamilton, T.A.3
  • 4
    • 0023203948 scopus 로고
    • Metabolism of cyclosporine A. II. Implication of the macrolide antibiotic inducible cytochrome P-450 3c from rabbit liver microsomes
    • Bertault-Peres P, Bonfils C, Fabre G, Just S, Cano JP, Maurel P. Metabolism of cyclosporine A. II. Implication of the macrolide antibiotic inducible cytochrome P-450 3c from rabbit liver microsomes. Drug Metab Dispos 1987; 15: 391–8.
    • (1987) Drug Metab Dispos , vol.15 , pp. 391-398
    • Bertault-Peres, P.1    Bonfils, C.2    Fabre, G.3    Just, S.4    Cano, J.P.5    Maurel, P.6
  • 5
    • 0021327063 scopus 로고
    • Disposition of cyclosporine in several animal species and man. I. Structural elucidation of its metabolites
    • Maurer G, Loosli HR, Schreier E, Keiler B. Disposition of cyclosporine in several animal species and man. I. Structural elucidation of its metabolites. Drug Metab Dispos 1984; 12: 120–6.
    • (1984) Drug Metab Dispos , vol.12 , pp. 120-126
    • Maurer, G.1    Loosli, H.R.2    Schreier, E.3    Keiler, B.4
  • 6
    • 0024208128 scopus 로고
    • Optimization of cyclosporine therapy in renal transplantation by a pharmacokinetic strategy
    • Kahan BD, Grevel J. Optimization of cyclosporine therapy in renal transplantation by a pharmacokinetic strategy. Transplantation 1988; 46: 631–44.
    • (1988) Transplantation , vol.46 , pp. 631-644
    • Kahan, B.D.1    Grevel, J.2
  • 9
    • 0023948006 scopus 로고
    • The free fraction of cyclosporine in plasma: clinical findings with a new method
    • Lindholm A, Henricsson S, Gang P. The free fraction of cyclosporine in plasma: clinical findings with a new method. Transplant Proc 1988; 20: Suppl 2: 377–81.
    • (1988) Transplant Proc , vol.20 , pp. 377-381
    • Lindholm, A.1    Henricsson, S.2    Gang, P.3
  • 10
    • 0023630918 scopus 로고
    • Central nervous system toxicity after liver transplantation: the role of cyclosporine and cholesterol
    • de Groen PC, Aksamit AJ, Rakela J, Forbes GS, Krom RAF. Central nervous system toxicity after liver transplantation: the role of cyclosporine and cholesterol. N Engl J Med 1987; 317: 861–6.
    • (1987) N Engl J Med , vol.317 , pp. 861-866
    • de Groen, P.C.1    Aksamit, A.J.2    Rakela, J.3    Forbes, G.S.4    Krom, R.A.F.5
  • 11
    • 0021684957 scopus 로고
    • Effect of hepatic dysfunction on oral cyclosporin pharmacokinetics in marrow transplant patients
    • Yee GC, Kennedy MS, Storb R, Thomas ED. Effect of hepatic dysfunction on oral cyclosporin pharmacokinetics in marrow transplant patients. Blood 1984; 64: 1277–9.
    • (1984) Blood , vol.64 , pp. 1277-1279
    • Yee, G.C.1    Kennedy, M.S.2    Storb, R.3    Thomas, E.D.4
  • 12
    • 0017086114 scopus 로고
    • Comparative study of in vitro and in vivo drug effects on cell-mediated cytotoxicity
    • Borel JF. Comparative study of in vitro and in vivo drug effects on cell-mediated cytotoxicity. Immunology 1976; 31: 631–41.
    • (1976) Immunology , vol.31 , pp. 631-641
    • Borel, J.F.1
  • 13
    • 0020043240 scopus 로고
    • Effect of cyclosporin A on human lymphocyte responses in vitro. III. CsA inhibits the production of T lymphocyte growth factors in secondary mixed lymphocyte responses but does not inhibit the response of primed lymphocytes to TCGF
    • Hess AD, Tutschka PJ, Santos GW. Effect of cyclosporin A on human lymphocyte responses in vitro. III. CsA inhibits the production of T lymphocyte growth factors in secondary mixed lymphocyte responses but does not inhibit the response of primed lymphocytes to TCGF. J Immunol 1982; 128: 355–9.
    • (1982) J Immunol , vol.128 , pp. 355-359
    • Hess, A.D.1    Tutschka, P.J.2    Santos, G.W.3
  • 14
    • 0020643660 scopus 로고
    • Inhibition of IL-2 production after human allogeneic bone marrow transplantation
    • Azogui O, Gluckman E, Fradelizi D. Inhibition of IL-2 production after human allogeneic bone marrow transplantation. J Immunol 1983; 131: 1205–8.
    • (1983) J Immunol , vol.131 , pp. 1205-1208
    • Azogui, O.1    Gluckman, E.2    Fradelizi, D.3
  • 15
    • 0022385218 scopus 로고
    • Pharmacodynamic assessment of in vivo cyclosporine effect on interleukin-2 production by lymphocytes of kidney transplant recipients
    • Yoshimura N, Kahan BD. Pharmacodynamic assessment of in vivo cyclosporine effect on interleukin-2 production by lymphocytes of kidney transplant recipients. Transplantation 1985; 40: 661–6.
    • (1985) Transplantation , vol.40 , pp. 661-666
    • Yoshimura, N.1    Kahan, B.D.2
  • 16
    • 0020639821 scopus 로고
    • Binding of cyclosporine by human lymphocytes and phospholipid vesicles
    • LeGrue SJ, Friedman AW, Kahan BD. Binding of cyclosporine by human lymphocytes and phospholipid vesicles. J Immunol 1983; 131: 712–8.
    • (1983) J Immunol , vol.131 , pp. 712-718
    • LeGrue, S.J.1    Friedman, A.W.2    Kahan, B.D.3
  • 17
    • 0021142639 scopus 로고
    • Cyclosporine does not prevent cytoplasmic calcium changes associated with lymphocyte activation
    • Metcalfe S. Cyclosporine does not prevent cytoplasmic calcium changes associated with lymphocyte activation. Transplantation 1984; 38: 161–4.
    • (1984) Transplantation , vol.38 , pp. 161-164
    • Metcalfe, S.1
  • 18
    • 0021846123 scopus 로고
    • Cyclosporine A binding to calmodulin: a possible site of action on T lymphocytes
    • Colombani PM, Robb A, Hess AD. Cyclosporine A binding to calmodulin: a possible site of action on T lymphocytes. Science 1985; 228: 337–9.
    • (1985) Science , vol.228 , pp. 337-339
    • Colombani, P.M.1    Robb, A.2    Hess, A.D.3
  • 19
    • 0022993125 scopus 로고
    • Does the binding of cyclosporine to calmodulin result in immunosuppression?
    • LeGrue SJ, Turner R, Weisbrodt N, Dedman JR. Does the binding of cyclosporine to calmodulin result in immunosuppression? Science 1986; 234: 68–71.
    • (1986) Science , vol.234 , pp. 68-71
    • LeGrue, S.J.1    Turner, R.2    Weisbrodt, N.3    Dedman, J.R.4
  • 20
    • 0024550939 scopus 로고
    • The inhibitory effect of cyclosporine on the nuclear proliferative response to a variety of T cell activators
    • Citterio F, Kahan BD. The inhibitory effect of cyclosporine on the nuclear proliferative response to a variety of T cell activators. Transplantation 1989; 47: 334–8.
    • (1989) Transplantation , vol.47 , pp. 334-338
    • Citterio, F.1    Kahan, B.D.2
  • 22
    • 0024959449 scopus 로고
    • Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins
    • Fischer G, Wittmann-Liebold B, Lang K, Kiefhaber T, Schmid FX. Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins. Nature 1989; 337: 476–8.
    • (1989) Nature , vol.337 , pp. 476-478
    • Fischer, G.1    Wittmann-Liebold, B.2    Lang, K.3    Kiefhaber, T.4    Schmid, F.X.5
  • 24
    • 0000693107 scopus 로고
    • Glucocorticoids selectively inhibit the transcription of the interleukin 1β gene and decrease the stability of interleukin 1β mRNA
    • Lee SW, Tsou A-P, Chan H, et al. Glucocorticoids selectively inhibit the transcription of the interleukin 1β gene and decrease the stability of interleukin 1β mRNA. Proc Natl Acad Sci U S A 1988; 85: 1204–8.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 1204-1208
    • Lee, S.W.1    Tsou, A.-P.2    Chan, H.3
  • 25
    • 0001240467 scopus 로고
    • Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription
    • Kronke M, Leonard WJ, Depper JM, et al. Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription. Proc Natl Acad Sci U S A 1984; 81: 5214–8.
    • (1984) Proc Natl Acad Sci U S A , vol.81 , pp. 5214-5218
    • Kronke, M.1    Leonard, W.J.2    Depper, J.M.3
  • 27
    • 0022446916 scopus 로고
    • Lymphokine and nonlymphokine mRNA levels in stimulated human T cells
    • Granelli-Piperno A, Andrus L, Steinman RM. Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. J Exp Med 1986; 163: 922–37.
    • (1986) J Exp Med , vol.163 , pp. 922-937
    • Granelli-Piperno, A.1    Andrus, L.2    Steinman, R.M.3
  • 28
    • 0018824706 scopus 로고
    • Effect of cyclosporin A on human lymphocyte responses in vitro. I. CsA allows for the expression of alloantigen-activated suppressor cells while preferentially inhibiting the induction of cytolytic effector lymphocytes in MLR
    • Hess AD, Tutschka PJ. Effect of cyclosporin A on human lymphocyte responses in vitro. I. CsA allows for the expression of alloantigen-activated suppressor cells while preferentially inhibiting the induction of cytolytic effector lymphocytes in MLR. J Immunol 1980; 124: 2601–8.
    • (1980) J Immunol , vol.124 , pp. 2601-2608
    • Hess, A.D.1    Tutschka, P.J.2
  • 31
    • 0023680294 scopus 로고
    • Effects of cyclosporine A on T cell development and clonal deletion
    • Jenkins MK, Schwartz RH, Pardoll DM. Effects of cyclosporine A on T cell development and clonal deletion. Science 1988; 241: 1655–8.
    • (1988) Science , vol.241 , pp. 1655-1658
    • Jenkins, M.K.1    Schwartz, R.H.2    Pardoll, D.M.3
  • 32
    • 0022542159 scopus 로고
    • Effects of cyclosporine on responses of murine B cells to T cell-derived lymphokines
    • O'Garra A, Warren DJ, Holman M, Popham A, Sanderson CJ, Klaus GG. Effects of cyclosporine on responses of murine B cells to T cell-derived lymphokines. J Immunol 1986; 137: 2220–4.
    • (1986) J Immunol , vol.137 , pp. 2220-2224
    • O'Garra, A.1    Warren, D.J.2    Holman, M.3    Popham, A.4    Sanderson, C.J.5    Klaus, G.G.6
  • 33
    • 0023925015 scopus 로고
    • Sensitivity of monocyte subpopulations to cyclosporine: arachidonate metabolism and in vitro antigen presentation
    • Esa AH, Paxman DG, Noga SJ, Hess AD. Sensitivity of monocyte subpopulations to cyclosporine: arachidonate metabolism and in vitro antigen presentation. Transplant Proc 1988; 20: Suppl 2: 80–6.
    • (1988) Transplant Proc , vol.20 , pp. 80-86
    • Esa, A.H.1    Paxman, D.G.2    Noga, S.J.3    Hess, A.D.4
  • 34
    • 0023900529 scopus 로고
    • Effects of cyclosporine on T lymphocytes and accessory cells from human blood
    • Granelli-Piperno A, Keane M. Effects of cyclosporine on T lymphocytes and accessory cells from human blood. Transplant Proc 1988; 20: Suppl 2: 136–42.
    • (1988) Transplant Proc , vol.20 , pp. 136-142
    • Granelli-Piperno, A.1    Keane, M.2
  • 35
    • 0022652556 scopus 로고
    • A randomized clinical trial of cyclosporine in cadaveric renal transplantation: analysis at three years
    • The Canadian Multicentre Transplant Study Group. A randomized clinical trial of cyclosporine in cadaveric renal transplantation: analysis at three years. N Engl J Med 1986; 314: 1219–25.
    • (1986) N Engl J Med , vol.314 , pp. 1219-1225
  • 36
    • 0021825045 scopus 로고
    • Clinical and experimental studies with cyclosporine in renal transplantation
    • Kahan BD, van Buren CT, Flechner SM, et al. Clinical and experimental studies with cyclosporine in renal transplantation. Surgery 1985; 97: 125–40.
    • (1985) Surgery , vol.97 , pp. 125-140
    • Kahan, B.D.1    van Buren, C.T.2    Flechner, S.M.3
  • 37
    • 0021967870 scopus 로고
    • A single institution, randomized, prospective trial of cyclosporin versus azathioprine antilymphocyte globulin for immunosuppression in renal allograft recipients
    • Najarian JS, Fryd DS, Strand M, et al. A single institution, randomized, prospective trial of cyclosporin versus azathioprine antilymphocyte globulin for immunosuppression in renal allograft recipients. Ann Surg 1985; 201: 142–57.
    • (1985) Ann Surg , vol.201 , pp. 142-157
    • Najarian, J.S.1    Fryd, D.S.2    Strand, M.3
  • 38
    • 0024427869 scopus 로고
    • The effect of cyclosporine on the use of hospital resources for kidney transplantation
    • Showstack J, Katz P, Amend W, et al. The effect of cyclosporine on the use of hospital resources for kidney transplantation. N Engl J Med 1989; 321: 1086–92.
    • (1989) N Engl J Med , vol.321 , pp. 1086-1092
    • Showstack, J.1    Katz, P.2    Amend, W.3
  • 39
    • 0021040778 scopus 로고
    • Cyclosporine in cardiac transplantation: a 2 1/2 year follow-up
    • Oyer PE, Stinson EB, Jamieson SW, et al. Cyclosporine in cardiac transplantation: a 2 1/2 year follow-up. Transplant Proc 1983; 15: Suppl 1: 2546–52.
    • (1983) Transplant Proc , vol.15 , pp. 2546-2552
    • Oyer, P.E.1    Stinson, E.B.2    Jamieson, S.W.3
  • 41
    • 0020082047 scopus 로고
    • Heart-lung transplantation: successful therapy for patients with pulmonary vascular disease
    • Reitz BA, Wallwork JL, Hunt SA, et al. Heart-lung transplantation: successful therapy for patients with pulmonary vascular disease. N Engl J Med 1982; 306: 557–64.
    • (1982) N Engl J Med , vol.306 , pp. 557-564
    • Reitz, B.A.1    Wallwork, J.L.2    Hunt, S.A.3
  • 42
    • 0023922756 scopus 로고
    • Experience with single-lung transplantation for pulmonary fibrosis
    • The Toronto Lung Transplant Group. Experience with single-lung transplantation for pulmonary fibrosis. JAMA 1988; 259: 2258–62.
    • (1988) JAMA , vol.259 , pp. 2258-2262
  • 43
    • 0021822464 scopus 로고
    • Cyclosporine as prophylaxis for graft-versus-host disease: a randomized study in patients undergoing marrow transplantation for acute nonlymphoblastic leukemia
    • Deeg HJ, Storb R, Thomas ED, et al. Cyclosporine as prophylaxis for graft-versus-host disease: a randomized study in patients undergoing marrow transplantation for acute nonlymphoblastic leukemia. Blood 1985; 65: 1325–34.
    • (1985) Blood , vol.65 , pp. 1325-1334
    • Deeg, H.J.1    Storb, R.2    Thomas, E.D.3
  • 44
    • 0020557126 scopus 로고
    • Cyclosporin A therapy in the treatment of intraocular inflammatory disease resistant to systemic corticosteroids and cytotoxic agents
    • Nussenblatt RB, Palestine AG, Chan CC. Cyclosporin A therapy in the treatment of intraocular inflammatory disease resistant to systemic corticosteroids and cytotoxic agents. Am J Ophthalmol 1983; 96: 275–82.
    • (1983) Am J Ophthalmol , vol.96 , pp. 275-282
    • Nussenblatt, R.B.1    Palestine, A.G.2    Chan, C.C.3
  • 45
    • 0022619110 scopus 로고
    • Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset: results of a multicentre double-blind trial
    • Feutren G, Papoz L, Assan R, et al. Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset: results of a multicentre double-blind trial. Lancet 1986; 2: 119–24.
    • (1986) Lancet , vol.2 , pp. 119-124
    • Feutren, G.1    Papoz, L.2    Assan, R.3
  • 46
    • 0023849461 scopus 로고
    • Factors associated with early remission of Type I diabetes in children treated with cyclosporine
    • Bougneres PF, Carel JC, Castano L, et al. Factors associated with early remission of Type I diabetes in children treated with cyclosporine. N Engl J Med 1988; 318: 663–70.
    • (1988) N Engl J Med , vol.318 , pp. 663-670
    • Bougneres, P.F.1    Carel, J.C.2    Castano, L.3
  • 47
    • 0000044052 scopus 로고
    • Cyclosporine (CY) induced remission of relapsing nephrotic syndrome (RNS) in children
    • abstract.
    • Tejani A, Butt K, Khawar MR, et al. Cyclosporine (CY) induced remission of relapsing nephrotic syndrome (RNS) in children. Kidney Int 1986; 29: 206. abstract.
    • (1986) Kidney Int , vol.29 , pp. 206
    • Tejani, A.1    Butt, K.2    Khawar, M.R.3
  • 48
    • 0023137311 scopus 로고
    • An open, controlled, randomized comparison of cyclosporine and azathioprine in the treatment of rheumatoid arthritis: a preliminary report
    • Orre O, Bjerkhoel F, Salvesen CF, et al. An open, controlled, randomized comparison of cyclosporine and azathioprine in the treatment of rheumatoid arthritis: a preliminary report. Arthritis Rheum 1987; 30: 88–92.
    • (1987) Arthritis Rheum , vol.30 , pp. 88-92
    • Orre, O.1    Bjerkhoel, F.2    Salvesen, C.F.3
  • 49
    • 0023928001 scopus 로고
    • Studies on the action of cyclosporine A against Schistosoma mansoni and other parasitic infections
    • Chappell LH, Thomson AW. Studies on the action of cyclosporine A against Schistosoma mansoni and other parasitic infections. Transplant Proc 1988; 20: Suppl 2: 291–7.
    • (1988) Transplant Proc , vol.20 , pp. 291-297
    • Chappell, L.H.1    Thomson, A.W.2
  • 50
    • 0021325222 scopus 로고
    • Phagocytic cell function in response to immunosuppressive therapy
    • Drath DB, Kahan BD. Phagocytic cell function in response to immunosuppressive therapy. Arch Surg 1984; 119: 156–60.
    • (1984) Arch Surg , vol.119 , pp. 156-160
    • Drath, D.B.1    Kahan, B.D.2
  • 51
    • 0023130690 scopus 로고
    • Cancers following cyclosporine therapy
    • Penn I. Cancers following cyclosporine therapy. Transplantation 1987; 43: 32–5.
    • (1987) Transplantation , vol.43 , pp. 32-35
    • Penn, I.1
  • 52
    • 0023893504 scopus 로고
    • Pregnancy after renal transplantation: severe intrauterine growth retardation during treatment with cyclosporin A
    • Pickrell MD, Sawers R, Michael J. Pregnancy after renal transplantation: severe intrauterine growth retardation during treatment with cyclosporin A. Br Med J 1988; 296: 825.
    • (1988) Br Med J , vol.296 , pp. 825
    • Pickrell, M.D.1    Sawers, R.2    Michael, J.3
  • 53
    • 0023103679 scopus 로고
    • Complications of cyclosporine-prednisone immunosuppression in 402 renal allograft recipients exclusively followed at a single center for from one to five years
    • Kahan BD, Flechner SM, Lorber MI, Golden D, Conley S, Van Buren CT. Complications of cyclosporine-prednisone immunosuppression in 402 renal allograft recipients exclusively followed at a single center for from one to five years. Transplantation 1987; 43: 197–204.
    • (1987) Transplantation , vol.43 , pp. 197-204
    • Kahan, B.D.1    Flechner, S.M.2    Lorber, M.I.3    Golden, D.4    Conley, S.5    Van Buren, C.T.6
  • 55
    • 0023262221 scopus 로고
    • Changes in facial appearance during cyclosporin treatment
    • Reznik VM, Jones KL, Durham BL, Mendoza SA. Changes in facial appearance during cyclosporin treatment. Lancet 1987; 1: 1405–7.
    • (1987) Lancet , vol.1 , pp. 1405-1407
    • Reznik, V.M.1    Jones, K.L.2    Durham, B.L.3    Mendoza, S.A.4
  • 57
    • 0021638052 scopus 로고
    • Deterioration in glucose metabolism in pancreatic transplant recipients after conversion from azathioprine to cyclosporine
    • Gunnarsson R, Klintmalm G, Lundgren G, et al. Deterioration in glucose metabolism in pancreatic transplant recipients after conversion from azathioprine to cyclosporine. Transplant Proc 1984; 16: 709–12.
    • (1984) Transplant Proc , vol.16 , pp. 709-712
    • Gunnarsson, R.1    Klintmalm, G.2    Lundgren, G.3
  • 58
    • 0023889773 scopus 로고
    • Cyclosporine A-induced alterations in rat hepatic glycogen metabolism
    • Betschart JM, Virji MA, ShinozukaH. Cyclosporine A-induced alterations in rat hepatic glycogen metabolism. Transplant Proc 1988; 20: Suppl 3: 880–4.
    • (1988) Transplant Proc , vol.20 , pp. 880-884
    • Betschart, J.M.1    Virji, M.A.2    Shinozuka, H.3
  • 59
    • 0023215854 scopus 로고
    • Cyclosporine inhibits testosterone biosynthesis in the rat testis
    • Rajfer J, Sikka SC, Lemmi C, Koyle MA. Cyclosporine inhibits testosterone biosynthesis in the rat testis. Endocrinology 1987; 121: 586–9.
    • (1987) Endocrinology , vol.121 , pp. 586-589
    • Rajfer, J.1    Sikka, S.C.2    Lemmi, C.3    Koyle, M.A.4
  • 60
    • 0023708625 scopus 로고
    • Cyclosporin-A in vivo produces severe osteopenia in the rat: effect of dose and duration of administration
    • Movsowitz C, Epstein S, Fallon M, Insmail F, Thomas S. Cyclosporin-A in vivo produces severe osteopenia in the rat: effect of dose and duration of administration. Endocrinology 1988; 123: 2571–7.
    • (1988) Endocrinology , vol.123 , pp. 2571-2577
    • Movsowitz, C.1    Epstein, S.2    Fallon, M.3    Insmail, F.4    Thomas, S.5
  • 61
    • 0021881063 scopus 로고
    • Thromboembolic complications and haemostatic changes in cyclosporin-treated cadaveric kidney allograft recipients
    • Vanrenterghem Y, Roels L, Lerut T, et al. Thromboembolic complications and haemostatic changes in cyclosporin-treated cadaveric kidney allograft recipients. Lancet 1985; 1: 999–1002.
    • (1985) Lancet , vol.1 , pp. 999-1002
    • Vanrenterghem, Y.1    Roels, L.2    Lerut, T.3
  • 62
  • 63
    • 0023228276 scopus 로고
    • Enhancement of procoagulant activity in stimulated mononuclear blood cells and monocytes by cyclosporine
    • Carlesen E, Prydz H. Enhancement of procoagulant activity in stimulated mononuclear blood cells and monocytes by cyclosporine. Transplantation 1987; 43: 543–8.
    • (1987) Transplantation , vol.43 , pp. 543-548
    • Carlesen, E.1    Prydz, H.2
  • 64
    • 0023916612 scopus 로고
    • Cyclosporine suppression of endothelial prostacyclin generation: a possible mechanism for nephrotoxicity
    • Voss BL, Hamilton KK, Samara EN, McKee PA. Cyclosporine suppression of endothelial prostacyclin generation: a possible mechanism for nephrotoxicity. Transplantation 1988; 45: 793–6.
    • (1988) Transplantation , vol.45 , pp. 793-796
    • Voss, B.L.1    Hamilton, K.K.2    Samara, E.N.3    McKee, P.A.4
  • 65
    • 0019851112 scopus 로고
    • Nephrotoxicity of cyclosporin A after allogeneic marrow transplantation: glomerular thromboses and tubular injury
    • Shulman H, Striker G, Deeg HJ, Kennedy M, Storb R, Thomas ED. Nephrotoxicity of cyclosporin A after allogeneic marrow transplantation: glomerular thromboses and tubular injury. N Engl J Med 1981; 305: 1392–5.
    • (1981) N Engl J Med , vol.305 , pp. 1392-1395
    • Shulman, H.1    Striker, G.2    Deeg, H.J.3    Kennedy, M.4    Storb, R.5    Thomas, E.D.6
  • 66
    • 0022400217 scopus 로고
    • De novo hemolytic uremic syndrome in renal transplant recipients immunosuppressed with cyclosporine
    • Van Buren D, Van Buren CT. Flechner SM, Maddox AM, Verani R, Kahan BD. De novo hemolytic uremic syndrome in renal transplant recipients immunosuppressed with cyclosporine. Surgery 1985; 98: 54–62.
    • (1985) Surgery , vol.98 , pp. 54-62
    • Van Buren, D.1    Van Buren, C.T.2    Flechner, S.M.3    Maddox, A.M.4    Verani, R.5    Kahan, B.D.6
  • 68
    • 0023928003 scopus 로고
    • Prospective serial renal function studies in patients with nonrenal disease treated with cyclosporine A
    • Tegzess AM, Doorenbos BM, Minderhound JM, Donker AJ. Prospective serial renal function studies in patients with nonrenal disease treated with cyclosporine A. Transplant Proc 1988; 20: Suppl 2: 390–3.
    • (1988) Transplant Proc , vol.20 , pp. 390-393
    • Tegzess, A.M.1    Doorenbos, B.M.2    Minderhound, J.M.3    Donker, A.J.4
  • 69
    • 0021201863 scopus 로고
    • Side effects of systemic cyclosporine in patients not undergoing transplantation
    • Palestine AG, Nussenblatt RB, Chan CC. Side effects of systemic cyclosporine in patients not undergoing transplantation. Am J Med 1984; 77: 652–6.
    • (1984) Am J Med , vol.77 , pp. 652-656
    • Palestine, A.G.1    Nussenblatt, R.B.2    Chan, C.C.3
  • 70
    • 0023370667 scopus 로고
    • Cyclosporine-induced acute renal dysfunction in the rat: evidence of arteriolar vasoconstriction with preservation of tubular function
    • English J, Evan A, Houghton DC, Bennett WM. Cyclosporine-induced acute renal dysfunction in the rat: evidence of arteriolar vasoconstriction with preservation of tubular function. Transplantation 1987; 44: 135–41.
    • (1987) Transplantation , vol.44 , pp. 135-141
    • English, J.1    Evan, A.2    Houghton, D.C.3    Bennett, W.M.4
  • 71
    • 0023178779 scopus 로고
    • Glomerular hemodynamics and hormonal participation in cyclosporine nephrotoxicity
    • Barros EJ, Boim MA, Ajzen H, Ramos OL, Schor N. Glomerular hemodynamics and hormonal participation in cyclosporine nephrotoxicity. Kidney Int 1987; 32: 19–25.
    • (1987) Kidney Int , vol.32 , pp. 19-25
    • Barros, E.J.1    Boim, M.A.2    Ajzen, H.3    Ramos, O.L.4    Schor, N.5
  • 72
    • 0022392306 scopus 로고
    • Effect of cyclosporine administration on renal hemodynamics in conscious rats
    • Murray BM, Palier MS, Ferris TF. Effect of cyclosporine administration on renal hemodynamics in conscious rats. Kidney Int 1985; 28: 767–74.
    • (1985) Kidney Int , vol.28 , pp. 767-774
    • Murray, B.M.1    Palier, M.S.2    Ferris, T.F.3
  • 74
    • 0024512372 scopus 로고
    • Dissociation between the immunosuppressive activity of cyclosporine derivatives and their effects on intracellular calcium signaling in mesangial cells
    • Goldberg HJ, Wong PY, Cole EH, Levy GA, Skorecki KL. Dissociation between the immunosuppressive activity of cyclosporine derivatives and their effects on intracellular calcium signaling in mesangial cells. Transplantation 1989; 47: 731–3.
    • (1989) Transplantation , vol.47 , pp. 731-733
    • Goldberg, H.J.1    Wong, P.Y.2    Cole, E.H.3    Levy, G.A.4    Skorecki, K.L.5
  • 75
    • 0023154693 scopus 로고
    • Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity
    • Coffman TM, Carr DR, Yarger WE, Klotman PE. Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity. Transplantation 1987; 43: 282–5.
    • (1987) Transplantation , vol.43 , pp. 282-285
    • Coffman, T.M.1    Carr, D.R.2    Yarger, W.E.3    Klotman, P.E.4
  • 76
    • 0023772597 scopus 로고
    • Effect of cyclosporine on urinary kallikrein excretion in patients with rheumatoid arthritis
    • Spragg J, Weinblatt ME, Coblyn J, Fraser P, Austen KF. Effect of cyclosporine on urinary kallikrein excretion in patients with rheumatoid arthritis. J Lab Clin Med 1988; 112: 324–32.
    • (1988) J Lab Clin Med , vol.112 , pp. 324-332
    • Spragg, J.1    Weinblatt, M.E.2    Coblyn, J.3    Fraser, P.4    Austen, K.F.5
  • 77
    • 0022409706 scopus 로고
    • Issues in the pathophysiology of nephrotoxic renal tubular cell injury pertinent to understanding cyclosporine nephrotoxicity
    • Weinberg JM. Issues in the pathophysiology of nephrotoxic renal tubular cell injury pertinent to understanding cyclosporine nephrotoxicity. Transplant Proc 1985; 17: Suppl 1: 81–90.
    • (1985) Transplant Proc , vol.17 , pp. 81-90
    • Weinberg, J.M.1
  • 78
    • 0023891040 scopus 로고
    • Histopathology of cyclosporine nephrotoxicity
    • Mihatsch MJ. Thiel G, Ryffel B. Histopathology of cyclosporine nephrotoxicity. Transplant Proc 1988; 20: Suppl 3: 759–71.
    • (1988) Transplant Proc , vol.20 , pp. 759-771
    • Mihatsch, M.J.1    Thiel, G.2    Ryffel, B.3
  • 79
    • 3242795637 scopus 로고
    • Prevention of posttransplant acute tubular necrosis by the calcium antagonist diltiazem: a prospective randomized study
    • Wagner K, Albrecht S, Neumayer HH. Prevention of posttransplant acute tubular necrosis by the calcium antagonist diltiazem: a prospective randomized study. Am J Nephrol 1987; 7: 287–91.
    • (1987) Am J Nephrol , vol.7 , pp. 287-291
    • Wagner, K.1    Albrecht, S.2    Neumayer, H.H.3
  • 80
    • 0024594255 scopus 로고
    • Stability of renal allograft function associated with long-term cyclosporine immunosuppressive therapy — five year follow-up
    • Lewis RM, Janney RP, Golden DL, et al. Stability of renal allograft function associated with long-term cyclosporine immunosuppressive therapy — five year follow-up. Transplantation 1989; 47: 266–72.
    • (1989) Transplantation , vol.47 , pp. 266-272
    • Lewis, R.M.1    Janney, R.P.2    Golden, D.L.3
  • 81
    • 0023854871 scopus 로고
    • The long-term course of cyclosporine-associated chronic nephropathy
    • Myers BD, Sibley R, Newton L, et al. The long-term course of cyclosporine-associated chronic nephropathy. Kidney Int 1988; 33: 590–600.
    • (1988) Kidney Int , vol.33 , pp. 590-600
    • Myers, B.D.1    Sibley, R.2    Newton, L.3
  • 82
    • 0022386592 scopus 로고
    • Management and prevention of cyclosporine nephrotoxicity after renal transplantation: use of low doses of cyclosporine, azathioprine, and prednisone
    • Simmons RL, Canafax DM, Strand M, et al. Management and prevention of cyclosporine nephrotoxicity after renal transplantation: use of low doses of cyclosporine, azathioprine, and prednisone. Transplant Proc 1985; 17: Suppl 1: 266–75.
    • (1985) Transplant Proc , vol.17 , pp. 266-275
    • Simmons, R.L.1    Canafax, D.M.2    Strand, M.3
  • 83
    • 0023818445 scopus 로고
    • Specific 3H radioimmunoassay with a monoclonal antibody for monitoring cyclosporine in blood
    • Ball PE, Munzer H, Keller HP, Abisch E, Rosenthaler J. Specific 3H radioimmunoassay with a monoclonal antibody for monitoring cyclosporine in blood. Clin Chem 1988; 34: 257–60.
    • (1988) Clin Chem , vol.34 , pp. 257-260
    • Ball, P.E.1    Munzer, H.2    Keller, H.P.3    Abisch, E.4    Rosenthaler, J.5
  • 84
    • 0023879731 scopus 로고
    • Serum cyclosporine concentration and risk of acute graft-versus-host disease after allogeneic bone marrow transplantation
    • Yee GC, Self SG, McGuire TR, Carlin J, Sanders JE, Deeg HJ. Serum cyclosporine concentration and risk of acute graft-versus-host disease after allogeneic bone marrow transplantation. N Engl J Med 1988; 319: 65–70.
    • (1988) N Engl J Med , vol.319 , pp. 65-70
    • Yee, G.C.1    Self, S.G.2    McGuire, T.R.3    Carlin, J.4    Sanders, J.E.5    Deeg, H.J.6
  • 85
    • 0021635362 scopus 로고
    • The value of serial serum trough cyclosporine levels in human renal transplantation
    • Kahan BD, Wideman CA. Reid M, et al. The value of serial serum trough cyclosporine levels in human renal transplantation. Transplant Proc 1984; 16: 1195–9.
    • (1984) Transplant Proc , vol.16 , pp. 1195-1199
    • Kahan, B.D.1    Wideman, C.A.2    Reid, M.3
  • 86
    • 0022625328 scopus 로고
    • Cyclosporine blood concentrations in the management of renal transplant recipients
    • Rogerson ME, Marsden JT, Reid KE, Bewick M, Holt DW. Cyclosporine blood concentrations in the management of renal transplant recipients. Transplantation 1986; 41: 276–8.
    • (1986) Transplantation , vol.41 , pp. 276-278
    • Rogerson, M.E.1    Marsden, J.T.2    Reid, K.E.3    Bewick, M.4    Holt, D.W.5
  • 87
    • 0021822199 scopus 로고
    • Comparison of the pharmacological profiles of cyclosporine, (Nva2)-cyclosporine and (Val2) dihydro-cyclosporine
    • Hiestand PC, Gunn HC, Gale JM, Ryffel B, Borel JF. Comparison of the pharmacological profiles of cyclosporine, (Nva2)-cyclosporine and (Val2) dihydro-cyclosporine. Immunology 1985; 55: 249–55.
    • (1985) Immunology , vol.55 , pp. 249-255
    • Hiestand, P.C.1    Gunn, H.C.2    Gale, J.M.3    Ryffel, B.4    Borel, J.F.5
  • 88
    • 0023149111 scopus 로고
    • Modification of experimental nephrotoxicity with fish oil as the vehicle for cyclosporine
    • Elzinga L, Kelley VE, Houghton DC, Bennett WM. Modification of experimental nephrotoxicity with fish oil as the vehicle for cyclosporine. Transplantation 1987; 43: 271–4.
    • (1987) Transplantation , vol.43 , pp. 271-274
    • Elzinga, L.1    Kelley, V.E.2    Houghton, D.C.3    Bennett, W.M.4
  • 89
    • 0024357488 scopus 로고
    • Enhancement of immunosuppression by substitution of fish oil for olive oil as a vehicle for cyclosporine
    • Kelley VE, Kirkman RL, Bastos M, Barrett LV, Strom TB. Enhancement of immunosuppression by substitution of fish oil for olive oil as a vehicle for cyclosporine. Transplantation 1989; 48: 98–102.
    • (1989) Transplantation , vol.48 , pp. 98-102
    • Kelley, V.E.1    Kirkman, R.L.2    Bastos, M.3    Barrett, L.V.4    Strom, T.B.5
  • 90
    • 0018186018 scopus 로고
    • Cyclosporin A in patients receiving renal allografts from cadaver donors
    • Calne RY, White DJ, Thiru S, et al. Cyclosporin A in patients receiving renal allografts from cadaver donors. Lancet 1978; 2: 1323–7.
    • (1978) Lancet , vol.2 , pp. 1323-1327
    • Calne, R.Y.1    White, D.J.2    Thiru, S.3
  • 91
    • 0023922129 scopus 로고
    • Cyclosporine mono-drug therapy
    • Salaman J. Cyclosporine mono-drug therapy. Transplant Proc 1988; 20: Suppl 3: 117–20.
    • (1988) Transplant Proc , vol.20 , pp. 117-120
    • Salaman, J.1
  • 92
    • 0018855683 scopus 로고
    • The use of cyclosporin A and prednisone in cadaver kidney transplantation
    • Starzl TE, Weil R III, Iwatsuki S, et al. The use of cyclosporin A and prednisone in cadaver kidney transplantation. Surg Gynecol Obstet 1980; 151: 17–26.
    • (1980) Surg Gynecol Obstet , vol.151 , pp. 17-26
    • Starzl, T.E.1    Weil, R.2    Iwatsuki, S.3
  • 93
    • 0001884366 scopus 로고
    • Cyclosporine plus methylprednisolone versus cyclophosphamide plus methylprednisolone as prophylaxis for graft-versus-host disease: a randomized, double-blind study in patients undergoing allogeneic marrow transplantation
    • Santos GW, Tutschka PJ, Brookmeyer R, et al. Cyclosporine plus methylprednisolone versus cyclophosphamide plus methylprednisolone as prophylaxis for graft-versus-host disease: a randomized, double-blind study in patients undergoing allogeneic marrow transplantation. Clin Transplant 1987; 1: 21.
    • (1987) Clin Transplant , vol.1 , pp. 21
    • Santos, G.W.1    Tutschka, P.J.2    Brookmeyer, R.3
  • 94
    • 0024503989 scopus 로고
    • Increased frequency of posttransplant lymphomas in patients treated with cyclosporin, azathioprine, and prednisone
    • Wilkinson AH, Smith JL, Hunsicker LG, et al. Increased frequency of posttransplant lymphomas in patients treated with cyclosporin, azathioprine, and prednisone. Transplantation 1989; 47: 293–6.
    • (1989) Transplantation , vol.47 , pp. 293-296
    • Wilkinson, A.H.1    Smith, J.L.2    Hunsicker, L.G.3
  • 95
    • 85005260900 scopus 로고    scopus 로고
    • Analysis of the interactions of immunosuppressive drugs with cyclosporine to inhibit DNA proliferation
    • (in press)
    • Vathsala A, Chou T-C, Kahan BD. Analysis of the interactions of immunosuppressive drugs with cyclosporine to inhibit DNA proliferation. Transplantation (in press).
    • Transplantation
    • Vathsala, A.1    Chou, T.-C.2    Kahan, B.D.3
  • 96
    • 0023820832 scopus 로고
    • Effects of the prostaglandin E1 analog misoprostol on cyclosporine nephrotoxicity
    • Palier MS. Effects of the prostaglandin E1 analog misoprostol on cyclosporine nephrotoxicity. Transplantation 1988; 45: 1126–31.
    • (1988) Transplantation , vol.45 , pp. 1126-1131
    • Palier, M.S.1
  • 97
    • 0023952366 scopus 로고
    • Additive effect of cyclosporine and verapamil on the inhibition of activation and function of human peripheral blood mononuclear cells
    • Weir MR, Peppier R, Gomolka D, Handwerger BS. Additive effect of cyclosporine and verapamil on the inhibition of activation and function of human peripheral blood mononuclear cells. Transplant Proc 1988; 20: Suppl 2: 240–4.
    • (1988) Transplant Proc , vol.20 , pp. 240-244
    • Weir, M.R.1    Peppier, R.2    Gomolka, D.3    Handwerger, B.S.4
  • 98
    • 0023909182 scopus 로고
    • Patient noncompliance: a major cause of later graft failure in cyclosporine-treated renal transplants
    • Didlake RH, Dreyfus K, Kerman RH, Van Buren CT, Kahan BD. Patient noncompliance: a major cause of later graft failure in cyclosporine-treated renal transplants. Transplant Proc 1988; 20: Suppl 3: 63–9.
    • (1988) Transplant Proc , vol.20 , pp. 63-69
    • Didlake, R.H.1    Dreyfus, K.2    Kerman, R.H.3    Van Buren, C.T.4    Kahan, B.D.5
  • 99
    • 0023915464 scopus 로고
    • Cyclosporine potentiates the immunosuppressive effects of anti-interleukin 2 receptor monoclonal antibody therapy
    • Kupiec-Weglinski JW, Hahn HJ, Kirkman RL, et al. Cyclosporine potentiates the immunosuppressive effects of anti-interleukin 2 receptor monoclonal antibody therapy. Transplant Proc 1988; 20: Suppl 2: 207–16.
    • (1988) Transplant Proc , vol.20 , pp. 207-216
    • Kupiec-Weglinski, J.W.1    Hahn, H.J.2    Kirkman, R.L.3
  • 100
    • 0021284818 scopus 로고
    • Prolongation of allograft survival by repeated cycles of donor antigen and cyclosporine in rat kidney transplantation
    • Yasumura T, Kahan BD. Prolongation of allograft survival by repeated cycles of donor antigen and cyclosporine in rat kidney transplantation. Transplantation 1984; 38: 418–23.
    • (1984) Transplantation , vol.38 , pp. 418-423
    • Yasumura, T.1    Kahan, B.D.2
  • 101
    • 0023113511 scopus 로고
    • Xenograft survival in two species combinations using total-lymphoid irradiation and cyclosporine
    • Knechtle SJ, Halperin EC, Bollinger RR. Xenograft survival in two species combinations using total-lymphoid irradiation and cyclosporine. Transplantation 1987; 43: 173–5.
    • (1987) Transplantation , vol.43 , pp. 173-175
    • Knechtle, S.J.1    Halperin, E.C.2    Bollinger, R.R.3


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