Large Increases in General Stability for Subtilisin BPN' through Incremental Changes in the Free Energy of Unfolding

Biochemistry

Volumn 28, Issue 18, 1989, Pages 7205-7213

  Pantoliano, Michael W ^a   Whitlow, Marc ^a   Wood, Jay F ^a   Dodd, Steven W ^a   Hardman, Karl D ^a   Rollence, Michele L ^a   Bryan, Philip N ^a,b  

^a Genex Corporation   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CALCIUM; SUBTILISIN;

ARTICLE; CHEMISTRY; CRYSTALLOGRAPHY; DIFFERENTIAL SCANNING CALORIMETRY; ENZYME STABILITY; KINETICS; METABOLISM; MUTATION; PH; PROTEIN CONFORMATION; PROTEIN DENATURATION; TEMPERATURE; THERMODYNAMICS;

AMINO ACIDS; CALCIUM; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY; CRYSTALLOGRAPHY; ENZYME STABILITY; HYDROGEN-ION CONCENTRATION; KINETICS; MUTATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; SUBTILISINS; SUPPORT, U.S. GOV'T, NON-P.H.S.; TEMPERATURE; THERMODYNAMICS;

EID: 0024962392     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00444a012     Document Type: Article

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