Chlorthalidone does not increase the hypotensive effect of nifedipine in essential hypertensives: A crossover multicentre study

Journal of Hypertension, Supplement

Volumn 7, Issue , 1989, Pages S250-S251

  Salvetti, Antonio ^a   Magagna, Armando ^a   Innocenti, Pierfranco ^b   Cagianelli, Augusto ^b   Cipriani, Marcello ^b   Gandolfi, Enio ^b   Del Prato, Carlo ^b   Ballestra, Anna Maria ^b   Saba, Paolo ^c   Giuntoli, Franco ^c   Panebianco, Giovanni ^d   Amigoni, Silvia ^d  

^a UNIVERSITY OF PISA   (Italy)

^b Unità Operativa USL7 ^*  (Italy)

^c Ricerca Medica Bayer ^*  (Italy)

^d NONE   (Italy)

Author keywords

Blood pressure; Interaction; Nifedipine and chlorthalidone combination

Indexed keywords

CHLORTALIDONE; NIFEDIPINE; PLACEBO;

ADULT; AGED; BLOOD PRESSURE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG COMBINATION; DRUG EFFECT; DRUG INTERACTION; ESSENTIAL HYPERTENSION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE;

ADULT; AGED; BLOOD PRESSURE; CHLORTHALIDONE; COMPARATIVE STUDY; DOUBLE-BLIND METHOD; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; HUMAN; HYPERTENSION; MALE; MIDDLE AGE; MULTICENTER STUDIES; NIFEDIPINE;

EID: 0024956895     PISSN: 09521178     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Sever PS, Poulter NR: Calcium antagonists and diuretics as combined therapy. J Hypertension 1987, 5 (suppl 4): S123-S126.
2. Magagna A, Abdel-Haq B, Pedrinelli R, Salvetti A: Does chlorthalidone increase the hypotensive effect of nifedipine? J Hypertension 1986, 4 (suppl 5): S519-S521.
3. Rosenthal J: Antihypertensive effects of nifedipine, mefruside and combination of both substances in patients with essential hypertension. In 5th International Adalat Symposium, 1982 edited by Kaltenbach M, Neufeld HN. Amsterdam: Excerpta Medica, 1982, pp 175-179.
4. Cappuccio FP, Markandu ND, MacGregor GA: Calcium antagonists and sodium balance: effect of changes in sodium intake and of the addition of a thiazide diuretic on the blood pressure lowering effect of nifedipine. J Cardiovasc Pharmacol 1987, 10 (suppl 10): S57-S60.
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