Correlation of erbB-2 gene amplification with low levels of estrogen and/or progesterone receptors in primary breast cancer : do erbB-2 products delineate hormone-independent tumors?

Biomedicine and Pharmacotherapy

Volumn 43, Issue 9, 1989, Pages 641-649

  Roux Dosseto, M ^a   Romain, S ^a   Dussault, N ^a   Martin, P M ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; PROTEIN ERB B; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CLINICAL ARTICLE; HUMAN; HUMAN CELL;

ADULT; AGE FACTORS; AGED; BREAST NEOPLASMS; CARCINOMA; FEMALE; GENE AMPLIFICATION; HUMAN; MIDDLE AGE; NEOPLASM STAGING; PROGNOSIS; RANDOM ALLOCATION; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE;

EID: 0024948183     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/0753-3322(89)90082-6     Document Type: Article

References (38)

1. Amplification of c-erbB-2 and aggressive human breast tumors?
2. Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading
3. Progression to steroid insensitivity can occur irrespective of the presence of functional steroid receptors
4. ErbB-2 is a potent oncogene when overexpressed in nIH 3T3
5. Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells
6. Stochastic development of invasive potential in rat mammary tumors induced by N-methyl-N-nitrosourea
7. Reversion toward an earlier stage of differentiation and loss of polarity during progression of N-methyl-N-nitrosourea-induced rat mammary tumors
8. The relationship of estradiol receptor and histological tumor differentiation with prognosis in human primary breast cancer
9. Identification of a novel v-erbB-related gene in a human mammary carcinoma
10. Estrogen receptor protein in breast cancer as a predictor and recurrence
11. Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer
12. Epidermal growth factor partially reverses the inhibitory effects of antiestrogen on T47D human breast cell growth
13. Normal and mutant β globin gene pre-mRNAs are faithfully and efficiently spliced in vitro
14. Her-2 cytoplasmic domain generates normal mitogenic and transforming signals in a chimeric receptor
15. Mapping of the human retinoic acid receptor to the q21 band of chromosome 17
16. Les recepteurs hormonaux dans les cancers du sein
17. Human p53 localized to short arm to chromosome 17
18. Two stage model for carcinogenesis : epidemiology of breast cancer in females
19. Human cancer and cellular oncogenes
20. Structure of an inverted duplication formed as a first step in gene amplification event : implication for a model of gene amplification
21. Altered glucocorticoid binding and action in response to epidermal growth factor in HBL 100 cells
22. Ligand activation of overexpressed epidermal growth factor receptors transforms NIH 3T3 fibroblasts
23. Genetic mapping of a human class II antigen β-chain cDNA clone to the SB region of the HLA complex
24. Decreased progesterone binding and attenuated progesterone action in cultured human breast carcinoma cells treated with epidermal growth factor.
25. The neu gent: an erbB-homologous gene
26. Hormone receptors in breast cancer
27. A v-erbB-related protooncogene, c-erbB-2, is distinct from c-erbB-1/epidermal growth factor—receptor gene and is amplified in human salivary gland adenocarcinoma
28. Human breast cancer : correlation of relapse and survival with amplification of the HER-2/neu oncogene
29. Amplification of the neu (c-erbB-2) oncogene in human mammary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene
30. Alterations to either c-erbB-2 (neu) or myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis
31. Epidermal growth factor-dependent transformation of a human EGF receptor proto-oncogene
32. Overexpression of the c-erbB-2 oncoprotein in human breast carcinomas : immunological assessment correlates with gene amplification
33. Steroid receptors in breast cancer
34. Similarity of protein encoded by the human c-erbB-2 gene to the epidermal growth factor
35. Human p53 cellular tumor antigen cDNA sequence and expression in COS cells
36. HER-2 amplification steroid receptors and epidermal growth factor receptor in primary breast cancer
37. Association of multiple copies of c-erbB-2 oncogene : its spread in breast cancer