Aminotransferase in disease

Clinics in Laboratory Medicine

Volumn 9, Issue 4, 1989, Pages 667-687

  Rej, R ^a  

^a WADSWORTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOTRANSFERASE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; PYRIDOXINE;

HEART INFARCTION; HUMAN; LIVER DISEASE; PRIORITY JOURNAL; REVIEW; BLOOD; ENZYMOLOGY; METABOLISM; REFERENCE VALUE;

ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; HUMAN; LIVER DISEASES; MYOCARDIAL INFARCTION; PYRIDOXINE; REFERENCE VALUES; TRANSAMINASES;

EID: 0024854618     PISSN: 02722712     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0272-2712(18)30598-5     Document Type: Review

References (182)

1. Aach R.D. Szmuness W. Mosley J.W. Serum alanine aminotransferase of donors in relation to the risk of non-A, non-B hepatitis in recipients. The transfusion-transmitted viruses study N Engl J Med 304 1981 989
2. Aldenhövel H.G. The influence of long-term anticonvulsant therapy with diphenyl-hydantoin and carbamazepine on serum gamma-glutamyltransferase, aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase Eur Arch Psychiatry Neurol Sci 237 1988 312
3. Alves P.S. Camilo E.A. Correia J.P. The SGOT/SGPT ratio in alcoholic liver disease Acta Med Port 3 1981 255
4. Amano J. Sunamori M. Okumura T. Studies on the significance of serum mito chondrial aspartate aminotransferase activity following ischemic cardiac arrest Jpn Circ J 46 1982 1345
5. Annoni G. Chirillo R. Swannie D. Prognostic value of mitochondrial aspartate amino transferase in acute myocardial infarction Clin Biochem 19 1986 235
6. Artur Y. Sanderink G.J. Maire I. Les macroenzymes dans le plasma humain. 2. Macro-gamma-glutamyltransférase, macroalanine aminopeptidase, macrophosphatase alcaline, macroaminotransferases et autre macroenzymes Ann Biol Clin (Paris) 45 1987 277
7. Bailey W.C. Weill H. DeRouen T.A. The effect of isoniazid on transaminase levels Ann Intern Med 81 1974 200
8. Balcke P. Schmidt P. Zazgornik J. Die intraerythrozytäre GOT-aktivität bei Urämie und ihr Verhalten unter Pyridoxinapplikation Klin Wochenschr 61 1983 859
9. Bartelik S. Ziolo H. Seasonal changes of serum aminotransferase activity Wiadomo-sci Lekarskie 33 1980 1427
10. Bavazzano P. Benassi S. Forzieri R. Identificazione dei valori de riferimento dei livelli ematici delle aminotransferasi AST ed ALT rilevati in 1262 apprendisti sottoposti a visita di idoneità al lavoro Quad Sclavo Diagn 16 1980 100
11. Benoni G. Johnell O. Rosberg B. Postoperative course of serum aminotransferases after total hip arthroplasty Acta Anaesthesiol Scand 28 1984 362
12. Berg B. Petersohn L. Helm G. Reference values for serum components in pregnant women Acta Obstet Gynecol Scand 63 1984 583
13. Bergmeyer H.U. Hørder M. Rej R. Approved recommendation (1985) on IFCC methods for the measurement of catalytic concentration of enzymes J Clin Chem Clin Biochem 24 1986 481 Part 3. IFCC method for alanine aminotransferase (L-alanine:2-oxoglutarate aminotransferase, EC 2.6.1.2
14. Bergmeyer H.U. Hørder M. Rej R. Approved recommendation (1985) on IFCC methods for the measurement of catalytic concentration of enzymes J Clin Chem Clin Biochem 24 1986 497 Part 2. IFCC method for aspartate aminotransferase (L-aspartate:2-oxoglutarate aminotransferase, EC 2.6.1.1
15. Biswas R. Post-transfusion non-A, non-B hepatitis: Significance of raised ALT and anti-HBc in blood donors [letter] Vox Sang 56 1989 63
16. Bloth B. de Faire U. Edhag O. Extreme elevation of transaminase levels in acute heart disease—a problem in differential diagnosis? Acta Med Scand 200 1976 281
17. 6 requirement in oral contraceptive users. I. Assessment by pyridoxal level and transferase activity in erythrocytes Am J Clin Nutr 32 1979 1015
18. Boyde T.R.C. Serum levels of the mitochondrial isoenzyme of aspartate aminotrans ferase in myocardial infarction and muscular dystrophy Enzymol Biol Clin 9 1968 385
19. Bradley D.W. Maynard J.E. Emery G. Transaminase activities in serum of long term hemodialysis patients Clin Chem 18 1972 1442
20. Brandt K-H Meulendijk P.N. Poulie N.J. Data on the determination of SGOT and SGPT activity in donor blood for the possible prevention of post-transfusion hepatitis Acta Med Scand 177 1965 321
21. Buehler H. Muench R. Schmid M. Cholestasis in alcoholic chronic pancreatitis. Diagnostic value of the transaminase ratio for differentiation between extra- and intra-hepatic cholestasis Scand J Gastroenterol 20 1985 851
22. Buitrago J.M.G. Deiz L.C.G. Battaner E. Human semen aspartate aminotransferase and alanine aminotransferase activity in male fertility studies Andrologia 13 1981 335
23. Börsch G. Baier J. Glocke M. Graphical analysis of laboratory data in the differential diagnosis of cholestasis: A computer-assisted prospective study J Clin Chem Clin Biochem 26 1988 509
24. Cepelak I. Lipovac K. Juretic D. Effects of neuroleptic phenothiazines on the activities of aminotransferases and γ-glutamyltransferase in serum and liver J Clin Chem Clin Biochem 24 1986 583
25. Chambers D.A. Crawford J.M. Mukherjee S. Aspartate aminotransferase in creases in crevicular fluid during experimental periodontitis in beagle dogs J Periodontol 55 1984 526
26. Chan A.W. Leong F.W. Schanley D.L. Transferrin and mitochondrial aspartate aminotransferase in young adult alcoholics Drug Alcohol Depend 23 1989 13
27. Chiarelli A. Abnormal transaminase levels in burned patients Plast Reconstr Surg 75 1985 134
28. Cohen J.A. Kaplan M.M. The SGOT/SGPT ratio—an indicator of alcoholic liver dis ease Dig Dis Sci 24 1979 835
29. Correia J.P. Alves P.S. Camilo E.A. SGOT-SGPT ratios Dig Dis Sci 26 1981 284
30. Corsi G.C. Valentini F. Bertazzon A. Effect of subtoxic amounts of furan, acetylfuran and methylene chloride on some serum enzymes of rat Boll Soc Ital Biol Sper 59 1983 1049
31. Crawford D.R. Reyna R.S. Weiner M.W. Effects of in vivo and in vitro dialysis on plasma transaminase activity Nephron 22 1978 418
32. Damsgaard T. Clausen N. West-Nielsen E. Early diagnosis of acute myocardial infarction by means of aspartate aminotransferase, creatine kinase and creatine kinase isoenzyme MB Dan Med Bull 26 1979 298
33. Davis G.L. Czaja A.J. Baggenstoss A.H. Prognostic and therapeutic implications of extreme serum aminotransferase elevation in chronic active hepatitis Mayo Clin Proc 57 1982 303
34. De Ritis F. Coltori M. Giusti G. Attività transaminsica del siero umano nell’epatite virale Minerva Med 46 1955 1207
35. De Ritis F. Coltori M. Giusti G. Serum-transaminase activities in liver disease Lancet 1 1972 685
36. Dennis P.M. Ericksen C.M. Interference of metronidazole (Flagyl) with serum aspar tate aminotransferase (AST) assays Med J Aust 2 1980 343
37. Deutsch J. Fritsch G. Gölles J. Effects of anticonvulsive drugs on the activity of gammaglutamyltransferase and aminotransferases in serum J Pediatr Gastroenterol Nutr 5 1986 542
38. Dhami M.S.I. Drangova R. Farkas R. Decreased aminotransferase activity of serum and various tissues in the rat after cefazolin treatment Clin Chem 25 1979 1263
39. Dhar A. Ghosal B. Banerjee P.K. Changes in free amino acid nitrogen concentration and transaminases in lead treated rats Int J Vitam Nutr Res 50 1980 416
40. Diehl A.M. Potter J. Boitnott J. Relationship between pyridoxal 5’-phosphate deficiency and aminotransferase levels in alcoholic hepatitis Gastroenterology 86 1984 632
41. Dodson W.E. Tasch V. Pharmacology of valproic acid in children with severe epi lepsy: Clearance and hepatotoxicity Neurology 31 1981 1047
42. Dufour D.R. Creatine kinase: aspartate aminotransferase activity ratio as an indicator of the source of an increased creatine kinase activity Clin Chem 34 1988 2506
43. Dufour D.R. LaGrenade A. Guerra J. Rapid serial enzyme measurements in evalua tion of patients with suspected myocardial infarction Am J Cardiol 63 1989 652
44. Dukes G.E. Sanders S.W. Russo J. Jr. Transaminase elevations in patients receiving bovine or porcine heparin Ann Intern Med 100 1984 646
45. Eichel H.J. Bukovsky J. Intracellular distribution pattern of rat liver glutamic-oxalacetic transaminase Nature 191 1961 243
46. Eriksen J. Olsen P.S. Thomsen A.C. Gamma-glutamyltranspeptidase, aspartate amino transferase, and erythrocyte mean corpuscular volume as indicators of alcohol consumption in liver disease Scand J Gastroenterol 19 1984 813
47. Farr M. Symmons D.P. Bacon P.A. Raised serum alkaline phosphatase and aspartate transaminase levels in two rheumatoid patients treated with sulphasalazine Ann Rheum Dis 44 1985 798
48. Feuer G. Balaza T. Farber T.M. Effect of cefazolin on aminotransferase activity in the rat J Toxicol Environ Health 7 1981 593
49. Fleisher G.A. Wakim K.G. Presence of two glutamic-oxalacetic transaminases in serum of dogs following acute injury of the liver Proc Soc Exp Biol Med 106 1961 283
50. 6 in the carpal tunnel syndrome based on a crossover clinical study Proc Natl Acad Sci 75 1978 3410
51. Foreman J. Prediction of viability of rabbit kidneys preserved by hypothermic perfu sion Cryobiology 12 1975 231
52. Fortson W.C. Tedesco F.J. Starnes E.C. Marked elevation of serum transaminase activity associated with extrahepatic biliary tract disease J Clin Gastroenterol 7 1985 502
53. Garcia-Webb P. Bhagat C.S. Beilby J.P. Plasma creatine kinase/aspartate aminotrans ferase ratio in the diagnosis of actue myocardial infarction [letter] Clin Chem 31 1985 498
54. Giesen P.L. Peltenburg H.G. de Zwaan C. Greater than expected alanine amino transferase activities in plasma and in hearts of patients with acute myocardial infarction Clin Chem 35 1989 279
55. Gitlin N. The serum glutamic oxaloacetic transaminase/serum glutamic pyruvic transaminase ratio as a prognostic index in severe acute viral hepatitis Am J Gastroenterol 77 1982 2
56. Goldberg D.M. Remtulla M.A. Lustig V. The diagnostic accuracy of three recom mended methods for serum aspartate aminotransferase assays in patients suspected of myocardial infarction and hepatobiliary diseases Clin Biochem 21 1988 323
57. Grimwood K. Coakley J.C. Hudson I.L. Serum aspartate aminotransferase levels after rotavirus gastroenteritis J Pediatr 112 1988 597
58. Guilland J.C. Bereksi Reguig B. Lequeu B. Evaluation of pyridoxine intake and pyridoxine status among aged institutionalised people Int J Vitam Nutr Res 54 1984 185
59. Guzelian P. Mills S. Fallon H.J. Liver structure and function in print workers exposed to toluene J Occup Med 30 1988 791
60. Gockeritz D. Lange C. Schmidt W. Höufigkeitsverteilung von Transaminase-Serumwerten Pharmazie 39 1984 435
61. Hafkenscheid J.C.M. Rosier J.G. van Dijk C.M. Apoenzyme content of serum amino transferases in patients with a renal allograft treated with cyclosporine A and azathioprine Clin Chim Acta 165 1987 21
62. Haymond R.E. Knight J.A. Venous serum, capillary serum, and capillary plasma com pared for use in determination of lactate dehydrogenase and aspartate aminotransferase activities Clin Chem 21 1975 896
63. Herlitz J. Hjalmarson Å Waldenström J. Relationship between different enzymatic estimations of the infarct size Acta Cardiol (Brux) 40 1985 217
64. Hetherington M.L. Buchanan G.R. Elevated serum transaminase values during ther apy for acute lymphoblastic leukemia correlate with prior blood transfusions Cancer 62 1988 1614
65. Himmelstein D.U. Woolhandler S.J. Adler R.D. Elevated SGOT/SGPT ratio in alco holic patients with acetaminophen hepatotoxicity Am J Gastroenterol 79 1984 718
66. Hirano K. Matsuda K. Adachi T. Determination of mitochondrial aspartate aminotransferase in serum Clin Chim Acta 155 1986 251
67. Hlynczak J.A. Kersten E. Wysocki K. Untersuchungen zur Aktivität einiger Enzyme im Serum HCN-exponierter Frauen Z Arztl Fortbild 74 1980 591
68. Hodgson M.J. Van Thiel D.H. Lauschus K. Liver injury tests in hazardous waste workers: The role of obesity J Occup Med 31 1989 238
69. Holzel W.G. Intra-individual variation of analytes in serum from patients with chronic liver diseases Clin Chem 33 1987 1133
70. Horder M. Hyltoff-Petersen P. Thygesen K. Clinical evaluation of models and markers of myocardial ischemia Upsala J Med Sci 88 1983 169
71. Horiuchi S. Kamimoto Y. Morino Y. Hepatic clearance of rat liver aspartate amino transferase isozymes: Evidence for endocytotic uptake via different binding sites on sinusoidal liver cells Hepatology 5 1985 376
72. Hultcrantz R. Glaumann H. Lindberg G. Liver investigation in 149 asympto matic patients with moderately elevated activities of serum aminotransferases Scand J Gastroenterol 21 1986 109
73. Husted S.E. Nielsen H.K. Koopmann H-D Heparin-induceret stigning i serum-aminotransferase Ugeskr Laeger 146 1984 647
74. Idéo G. de Franchis R. Bellobuono A. Serum cytosolic/mitochondrial enzyme ratio: A tool for the estimation of the severity of acute hepatitis Z Klin Chem Klin Biochem 10 1972 74
75. Idéo G. de Franchis R. Bellobuono A. Aspartate aminotransferase isoenzymes in human serum in various liver diseases Enzyme 12 1971 529
76. Ink O. Boutron A. Hanny P. Place du taux serique de l’ aspartate aminotransfer ase mitochondriale comme marquer d’intoxication chez le cirrhotique alcoolique Presse Med 18 1989 111
77. Inoue M. Hori M. Nishimoto Y. Immunological determination of serum m-AST activity in patients with acute myocardial infarction Br Heart J 40 1978 1251
78. Irving A.D. Kennedy D. Serum “cardiac” enzyme levels after laparotomy. Of value in the diagnosis of postoperative myocardial infarction? J R Coll Surg Edinb 29 1984 252
79. Iwasaki Y. Ohkubo A. Kamei S. Serial determination of serum GOT isozyme activities for the evaluation of acute hepatic damage Gastroenterol Jpn 75 1978 34
80. Jung K. Blank W. Scholz D. Effect of immunosuppressive treatment on amino transferase activities in serum of renal-transplant recipients [letter] Clin Chem 34 1988 2180
81. Jung K. Ohlrich B. Mildner D. Pyridoxal phosphate activation of aminotransfer ases in serum of patients with kidney transplants Clin Chem 27 1981 205
82. Jung K. Pergande M. Rej R. Mitochondrial enzymes in human serum: Compara tive determinations of glutamate dehydrogenase and mitochondrial aspartate aminotransferase in healthy persons and patients with chronic liver diseases Clin Chem 31 1985 239
83. Kanemitsu F. Aspartate aminotransferase-immunoglobulin G complexes in sera of two patients with acute hepatitis and immunoblastic lymphadenopathy [letter] Clin Chim Acta 161 1986 353
84. Karmen A. Wróblewski F. LaDue J.S. Transaminase activity in human blood J Clin Invest 34 1955 126
85. Kay A.J. Lilleyman J.S. Bennett M.J. T-Lymphoblastic leukaemia and aspartate aminotransferase Leuk Res 6 1982 865
86. Knopp R.H. Bergelin R.O. Wahl P.W. Clinical chemistry alterations in pregnancy and oral contraceptive use Obstet Gynecol 66 1985 682
87. Kobylak L.J. Elevated serum transaminase as a presenting clue for precirrhotic he mochromatosis Henry Ford Hosp Med J 32 1984 46
88. Korns R.F. Fasce C.F. Community outbreak of infectious hepatitis. Assays of SGOT and Australian serum hepatitis antigen NY State J Med 72 1972 1583
89. Kumagai R. Tokiwa K. Nakayashiki N. Glutamate-pyruvate transaminase (GPT) variant found in a disputed paternity case Tohoku J Exp Med 153 1987 383
90. Kwong T.C. Fitzpatrick P.G. Rothbard R.L. Activities of some enzymes in serum after therapy with intracoronary streptokinase in acute myocardial infarction Clin Chem 30 1984 731
91. Lacher D.A. Paolino M.J. Discriminant analysis of laboratory tests in patients admitted to a coronary care unit Clin Chem 34 1988 1099
92. Lacour B. Vassault A. Degos F. Interet de Faddition in vitro de phosphate de pyridoxal dans la determination de Factivite catalytique des amino-transferases dans une population de transplantes renaux Clin Chim Acta 120 1982 1
93. Leary P.M. Liver function in children receiving treatment with the anticonvulsant sodium valproate S Afr Med J 61 1982 783
94. Ledwich J.R. Wong C.J. Duration of chest pain associated with acute myocardial infarction: A predictor of long-term prognosis Can Med Assoc J 132 1985 249
95. Leppänen E. Grasbeck R. The effect of the order of filling tubes after venipuncture on serum potassium, total protein, and aspartate and alanine aminotransferases Scand J Clin Lab Invest 46 1986 189
96. Lewis D.W. Berman P.H. Elevated transaminase levels and neuromuscular pathology [letter] Am J Dis Child 139 1985 860
97. Linnet K. Andersen J.R. Morup L. Liver function under long-term treatment with neuroleptic drugs assessed by serum concentrations of bile acids, alkaline phosphatase, and aspartate aminotransferase Acta Psychiatr Scand 67 1983 315
98. Lotgering F.K. Lind J. Huikeshoven F.J. Elevated serum transaminase levels during ritodrine administration Am J Obstet Gynecol 155 1986 390
99. Lumeng L. New diagnostic markers of alcohol abuse Hepatology 6 1986 742
100. Masse P. Vuilleumier J.P. Weiser H. Is pyridoxine an essential nutrient for bone? Int J Vitam Nutr Res 58 1988 295
101. Matloff D.S. Selinger M.J. Kaplan M.M. Hepatic transaminase activity in alcoholic liver disease Gastroenterology 78 1980 1389
102. Mayer A.D. McMahon M.J. Biochemical identification of patients with gallstones asso ciated with acute pancreatitis on the day of admission to hospital Ann Surg 201 1985 68
103. Meloni T. Pilo G. Gallisai D. Serum glutamic oxalacetic transaminase, glutamic pyruvic transaminase, gamma-glutamyl transpeptidase and glutamic dehydrogenase levels in favism Acta Haematol 62 1979 71
104. Meng X.Y. Xu K.C. Yang Z.H. Clinical appraisal of serum isozymes of LDH and GOT in the diagnosis of hepatobiliary diseases Chin Med J [Engl] 100 1987 146
105. Minar E. Ehringer H. Hirschl M. Transaminasenanstieg: eine weigehend unbe-kannte Nebenwirkung der Heparintherapie Dtsch Med Wochenschr 105 1980 1713
106. Mock D.M. Scott M. Mock N.I. The proportion of mitochondrial isoenzyme of aspartate aminotransferase is not elevated in Reye’s syndrome Pediatr Res 17 1983 884
107. Mortimer D. Bramley T.A. Glutamic-oxalacetic transaminase leakage from human spermatozoa as an indicator of cryodamage Arch Androl 6 1981 337
108. Mortimer D. Johnson A.V. Long Simpson L.K. Glutamic-oxaloacetic transaminase isozymes in human seminal plasma and sperm extracts Int J Fertil 33 1988 291
109. Nagamine M. Okochi K. Complexes of immunoglobulins A and G with aspartate aminotransferase isoenzymes in serum Clin Chem 29 1983 379
110. Nalpas B. Vassault A. Charpin S. Serum mitochondrial aspartate aminotransfer ase as a marker of chronic alcoholism: Diagnostic value and interpretation in a liver unit Hepatology 6 1986 608
111. Nalpas B. Vassault A. Le Guillou A. Serum activity of mitochondrial aspartate aminotransferase: A sensitive marker of alcoholism with or without alcoholic hepatitis Hepatology 4 1984 893
112. Nealon D.A. Rej R. Quantitation of aspartate aminotransferase isoenzymes after elec trophoretic separation Anal Biochem 161 1987 64
113. Nemesanszky E. Lott J.A. Arato M. Changes in serum enzymes in moderate drinkers after an alcohol challenge Clin Chem 34 1988 525
114. Niblock A.E. Leung F.Y. Henderson A.R. Serum aspartate aminotransferase storage and the effect of pyridoxal phosphate J Lab Clin Med 108 1986 461
115. Nielsen H.K. Husted S.E. Koopmann H.D. Heparin-induced increase in serum levels of aminotransferases. A controlled clinical trial Acta Med Scand 215 1984 231
116. Ohisalo J.J. Andersson B.M. Viljanen A A Is there a brain tyrosine aminotransfer ase? Biochem J 204 1982 621
117. Ohno H. Watanabe H. Kishihara C. Effect of physical exercise on the activity of GOT isozyme in human plasma Tohoku J Exp Med 126 1978 371
118. Okuno F. Ishii H. Kashiwazaki K. Increase in mitochondrial GOT (m-GOT) activity after chronic alcohol consumption: Clinical and experimental observations Alcohol 5 1988 49
119. Olsson K.S. Ritter B. Lundin P.M. Liver affection in iron overload studied with serum ferritin and serum aminotransferases Acta Med Scand 217 1985 79
120. Ostenbroek R.J. Willems G.M. Boumans M.L. Liver damage as a potential source of error in the estimation of myocardial infarct size from plasma creatine kinase activity Cardiovasc Res 19 1985 113
121. Osifo B.O.A. Adeyokunnu A. Serum aminotransferase activities in sickle cell children during crises ActaTrop (Basel) 41 1984 173
122. Osifo B.O.A. Bolodeoku J.O. Serum aspartate and alanine aminotransferase activities in protein energy malnutrition Enzyme 28 1982 300
123. Panteghini M. Falsetti F. Chiari E. Determination of aspartate aminotransferase isoeyzymes in hepatic diseases—preliminary findings Clin Chim Acta 128 1983 133
124. Panteghini M. Pagani F. Cuccia C. Activity of serum aspartate aminotransferase isoenzymes in patients with acute myocardial infarction Clin Chem 33 1987 67
125. Pappas N.J. Jr. Source of increased serum aspartate and alanine aminotransferase: Cycloheximide effect on carbon tetrachloride hepatotoxicity Clin Chim Acta 154 1986 181
126. Penttila I.M. Jokela H.A. Viitala A.J. Activities of aspartate and alanine amino transferases and alkaline phosphatase in sera of healthy subjects Scand J Clin Lab Invest 35 1975 275
127. Plebani M. Bonvicini P. De Besi T. Reference values for alanine and aspartate aminotransferase (ALT and AST) optimized by addition of pyridoxal phosphate Enzyme 25 1980 346
128. Porikos K.P. Van Itallie T.B. Diet-induced changes in serum transaminase and triglyc eride levels in healthy adult men Am J Med 75 1983 624
129. Rautonen J. Siimes M.A. Elevated serum transaminase activity at diagnosis is asso ciated with rapidly progressing disease in children with acute lymphoblastic leukemia Cancer 61 1988 754
130. Rej R. Review: The role of coenzymes in clinical enzymology Ann Clin Lab Sci 7 1977 455
131. Rej R. Aspartate aminotransferase activity and isoenzyme proportions in human liver tissues Clin Chem 24 1978 1971
132. Rej R. Quantitation of aspartate aminotransferase isoenzymes by immunologic methods: Use of antibodies directed against the mitochondrial isoenzyme Clin Biochem 12 1979 250
133. Rej R. An immunochemical procedure for determination of mitochondrial aspartate aminotransferase in human serum Clin Chem 26 1980 1694
134. Rej R. Multiple molecular forms of human cytoplasmic aspartate aminotransferase Clin Chim Acta 112 1981 1
135. Rej R. A convenient continuous-rate spectrophotometric method for determination of amino acid substrate specificity of aminotransferases: Application to isoenzymes of aspartate aminotransferase Anal Biochem 119 1982 205
136. Rej R. Measurement of aminotransferases CRC Crit Rev Clin Lab Sci 21 1984 99 Part 1. Aspartate aminotransferase
137. Rej R. Bretaudiere J-P Graffunder B. Measurement of aspartate aminotransferase isoenzymes: Six procedures compared Clin Chem 27 1981 535
138. Rej R. Horder M. Hyltoft-Petersen P. Isoenzymes of aspartate aminotransferase and creatine kinase in acute myocardial infarction Clin Chem 29 1983 1233
139. Rej R. Keese C.R. Giaever I. Direct immunologic determination of aspartate amino transferase isoenzymes in human serum Clin Chem 26 1981 969
140. Rej R. Nealon D.A. Horder M. Aspartate aminotransferase isoenzymes Bergmeyer H.U. 3rd Ed. Methods of Enzymatic Analysis 3 1983 Verlag Chemie Weinheim 434
141. Rej R. Vanderlinde R.E. Effects of temperature on the steady-state kinetics and mea surement of aspartate aminotransferases Clin Chem 27 1981 213
142. Reverberi R. Ferrari L. Ferrari R. Aspartate aminotransferase and pyruvate kinase activities in erythrocytes separated according to age by gradient centrifugation Haematologica (Pavia) 71 1986 13
143. Rissing J.P. Newman C. Moore W.L. Jr. Artifactual depression of serum glutamic oxaloacetic transaminase by metronidazole Antimicrob Agents Chemother 14 1978 636
144. Roberts P. Hubbard R.W. Kerstein M.D. Serum glutamic-oxaloacetic transaminase (SGOT) as a predictor of recurrent heat illness Milit Med 152 1987 408
145. Ross J.H. Attwood E.C. Atkin G.E. A study on the effects of severe repetitive exercise on serum myoglobin, creatine kinase, transaminases and lactate dehydrogenase Q J Med 52 1983 268
146. Rotenberg Z. Weinberger I. Davidson E. Does determination of serum aspartate aminotransferase contribute to the diagnosis of acute myocardial infarction? Am J Clin Pathol 91 1989 91
147. Russell A.S. Sturge R.A. Smith M.A. Serum transaminases during salicylate therapy Br Med J 2 1971 428
148. Rutledge J. Andersen J. Fink C.W. Persistent hypertransaminasemia as the presenting finding of childhood muscle disease Clin Pediatr (Phila) 24 1985 500
149. Salaspuro M. Use of enzymes for the diagnosis of alcohol-related organ damage Enzyme 37 1987 87
150. Schiele F. Artur Y. Varasteh A. Serum mitochondrial aspartate aminotransferase activity: Not useful as a marker of excessive alcohol consumption in an unselected population Clin Chem 35 1989 926
151. Schlang H.A. Kirkpatrick C.A. The effect of physical exercise on serum transaminase Am J Med Sci 242 1961 338
152. Schlesinger D. Haasa J. Manczak M. Atypical segregation in the GPT group system. Determination of types and activity of enzyme in families Arch Immunol Ther Exp (Warsz) 34 1986 149
153. Schmidt E. Schmidt F.W. Chemnitz G. The Szasz-ratio (CK/GOT) as example for the diagnostic significance of enzyme ratios in serum Klin Wochenschr 58 1980 709
154. Schwarz K.B. Burris G.C. deMello D.E. Prolonged elevation of transaminase concentration in children with unsuspected myopathy Am J Dis Child 138 1984 1121
155. Sharma S.K. Aggarwal A. Pal L.S. Mushroom (Amanita phalloides) poisoning with special reference to serum enzyme levels J Indian Med Assoc 75 1980 213
156. Shiojima S. Hasegawa K. Ishihara N. Subclinical increases in serum transami nase activities among female workers exposed to toluene at sub-OEL levels Ind Health 21 1983 123
157. 6 rather than a deficiency of a dependency state Biochem Biophys Res Commun 95 1980 1126
158. Siegel R.J. Edwalds G. Rej R. Distribution of cytosolic and mitochondrial aspar tate aminotransferase in normal, ischemic, and necrotic myocardium. An immuno-histochemical study Lab Invest 51 1984 648
159. Siest G. Schiele F. Galteau M-M Aspartate aminotransferase and alanine aminotransferase activities in plasma: Statistical distributions, individual variations, and reference values Clin Chem 21 1975 1077
160. Smilkstein M.J. Knapp G.L. Kulig K.W. Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985) N Engl J Med 319 1988 1557
161. Smit M.J. Wijnholds J. Duursma A.M. Plasma clearance of mitochondrial aspar tate aminotransferase in the rat: Competition with mitochondrial malate dehydrogenase Biomed Biochim Acta 45 1986 1557
162. Smith A.F. Wong P.C-P. Oliver M.F. Release of mitochondrial enzymes in acute myo cardial infarction J Mol Med 2 1977 265
163. Sonntag O. Haemolysis as an interference factor in clinical chemistry J Clin Chem Clin Biochem 24 1986 127
164. Sood S.C. Gulati S.C. Kumar M. Cerebral metabolism following brain injury. III. Transaminase changes Neurochirurgia 23 1980 182
165. Swick R.W. Barnstein P.L. Stange J.L. The metabolism of mitochondrial proteins. I. Distribution and characterization of the isozymes of alanine aminotransferase in rat liver J Biol Chem 240 1965 3334
166. Takashima Y. Furukawa T. Effects of overweight and habitual drinking on serum transaminase levels Keio J Med 33 1984 1
167. Talley N.J. Roth A. Woods J. Diagnostic value of liver biopsy in alcoholic liver disease J Clin Gastroenterol 10 1988 647
168. Thaler M.M. Clinical and enzymatic indices of hepatic dysfunction in Reye’s syndrome Crocker J.F.S. Reye’s Syndrome II 1978 Grune & Stratton New York 115
169. Tiidus P.M. Ianuzzo C.D. Effects of intensity and duration of muscular exercise on delayed soreness and serum enzyme activities Med Sci Sports Exerc 15 1983 461
170. Tola S. Nordman C-H Serum creatinine concentrations s-GOT and s-GPT activities and lead exposure Int Arch Occup Environ Health 39 1977 37
171. Trautschold I. Werle E. Transaminasen Lang K. Lehnartz E. 10th Ed. Hoppe-Seyler/Thierfelder Handbuch der Physiologischund Pathologisch-Chemischen Analyse für Ärzte, Bioloeen und Chemiker Vol.6B 1966 Springer-Verlag Berlin 306
172. Van Lente F. McHugh A. Pippenger C.E. Carbamylation of apo-aspartate aminotrans ferase: A possible mechanism for enzyme inactivation in uremic patients Clin Chem 32 1986 2107
173. Vincent-Viry M. Galteau M.M. Schiele F. Aspartate aminotransferase Siest G. Henny J. Schiele F. Young D.S. Interpretation of Clinical Laboratory Tests. Reference Values and Their Biological Variation 1985 Biomedical Publications Foster City 130
174. Vincent-Viry M. Schiele F. Galteau M.M. Alanine aminotransferase Siest G. Henny J. Schiele F. Young D.S. Interpretation of Clinical Laboratory Tests. Reference Values and Their Biological Variation 1985 Biomedical Publications Foster City 69
175. Wei J.Y. Markis J.E. Malagold M. Time course of serum cardiac enzymes after intracoronary thrombolytic therapy. Creatine kinase, creatine kinase MB isozyme, lactate dehydrogenase, and serum glutamic-oxaloacetic transaminase Arch Intern Med 145 1985 1596
176. Weidner N. Lott J.A. Yale V.D. Immunoglobulin-complexed aspartate amino transferase Clin Chem 29 1983 382
177. Weinstein L. Preeclampsia/eclampsia with hemolysis, elevated liver enzymes, and thrombocytopenia Obstet Gynecol 66 1985 657
178. Whitfield J.B. Martin N.G. Individual differences in plasma ALT, AST and GGT: Contributions of genetic and environmental factors, including alcohol consumption Enzyme 33 1985 61
179. Williams A.L. Hoofnagle J.H. Ratio of serum aspartate to alanine aminotransferase in chronic hepatitis. Relationship to cirrhosis Gastroenterology 95 1988 734
180. Wróblewski F. LaDue J.S. Serum glutamic oxalacetic transaminase activity as an index of liver cell injury: A preliminary report Ann Intern Med 43 1955 345
181. Yamamoto T. Suou T. Hirayama C. Elevated serum aminotransferase induced by isoniazid in relation to isoniazid acetylator phenotype Hepatology 6 1986 295
182. Zetzel L. Kaplan H. Dussik K.T. Liver-function tests in patients receiving iproniazid Am J Dig Dis 4 1959 1027