Clinical significance of MRI white matter lesions in the elderly

Neurology

Volumn 39, Issue 11, 1989, Pages 1470-1474

  Hunt, A L ^a   Orrison, W W ^a   Yeo, R A ^b   Haaland, K Y ^b,c   Rhyne, R L ^a   Garry, P J ^a   Rosenberg, G A ^a,c  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c VA Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; BRAIN INJURY; HUMAN; HUMAN EXPERIMENT; MEMORY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; WHITE MATTER;

AGED; AGED, 80 AND OVER; AGING; BRAIN; COGNITION; HUMAN; MAGNETIC RESONANCE IMAGING; MIDDLE AGE; REGRESSION ANALYSIS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0024853630     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/wnl.39.11.1470     Document Type: Article

References (30)

1. Kinkel WR, Jacobs L, Polachini I, Bates V, Heffner RR Jr. Subcortical arteriosclerotic encephalopathy (Binswanger’s disease): computed tomographic. nuclear magnetic resonance, and clinical correlations. Arch Neural 1985;42:951–959.
2. Awad IA, Spetzler RF, Hodak JA, Awad CA, Cary R. Incidental subcortical lesions identified on magnetic resonance imaging in the elderly. I. Correlation with age and cerebro vascular risk factors. Stroke 1986;6:1084–1089.
3. George AE, de Leon MJ, Kalnin A, Rosner L, Goodgold A, Chase N. Leukoencephalopathy in normal and pathologic aging: 2. MRI of brain lucencies. AJNR 1986;7:567–570.
4. Gerard G, Weisberg LA. MRI periventricular lesions in adults. Neurology 1986;36:998–1001.
5. Lechner H, Schmidt R, Bertha G, Justich E, Offenbacher H, Schneider G. Nuclear magnetic resonance image white matter lesions and risk factors for stroke in normal individuals. Stroke 1988;19:263–266.
6. Fazekas P, Offenbacher H, Fuchs S, Schmidt R, Niederkorn K, Homer S, Lechner H. Criteria for an increased specificity of MRI interpretation in elderly subjects with suspected multiple sclerosis. Neurology 1988;38:1822–1825.
7. Rosenberg GA. Binswanger’s disease. Arch Neurol 1986;43:641.
8. Garry PJ, Goodwin JS, Hunt WC, Hooper EM, Leonard HG. Nutritional status in a healthy elderly population. Am J Clin Nutr 1982;36:319–331.
9. Haaland KY, Linn RT, Hunt WC, Goodwin JS. A normative study of Russell’s variant of the Wechsler Memory Scale in a healthy elderly population, J Consult Clin Psychol 1983;51:878–881.
10. Wechsler D. Wechsler Adult Intelligence Scale-Revised. (WAISR). New York: Psychological Corporation, 1981.
11. Kaplan E, Goodglass H, Weintraub S. The Boston naming test. Philadelphia: Lea & Febiger. 1983.
12. Lezak MD. Neuropsychological assessment, 2nd ed. New York: Oxford Press, 1983.
13. DeRenzi E, Vignolo LA. The Token test: A sensitive test to detect disturbances in aphasics. Brain 1962;85:669–678.
14. Hooper HE. The Hooper visual organization test. Los Angeles: Western Psychological Services, 1958.
15. Wechsler D. A standardized memory scale for clinical use. J Psychol 1945;19:87–93.
16. Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementis of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 1968;114:797–811.
17. Jacobs JW, Bernhard ME, Delgado A. Screening for organic mental syndromes in the medically ill. Ann Intern Med 1977:86:40.
18. Folstein MF, Folstein SE, McHugh PR. Mini-mental state. J Psychiatr Res 1975;12:189–198.
19. Luria AR. Higher cortical functions in man, 2nd ed. New York, Basic Books, 1966.
20. Christensen AL. Luria’s neuropsychological investigators. Copenhagen: Munksgaard, 1979.
21. Zimmerman RD, Fleming CA, Lee BP, Saint-Louis LA, Deck MD. Periventricular hyperintensity as seen by magnetic resonance: prevalence and significance. AJNR 1986;7:13–20.
22. Brant-Zawadski M, Fein G, Van Dyke C, Kiernan R, Davenport L, de Groot J. MR imaging of the aging brain: patchy white-matter lesions and dementia. AJNR 1985;6:675–682.
23. Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA. MR signal abnormalities at 1.5T in Alzheimer’s dementia and normal aging. AJNR 1987;8:421–426.
24. Goto K, Ishii N, Fukasawa H. Diffuse white-matter disease in the geriatric population: a clinical, neuropathological and CT study. Radiology 1981;141:687–695.
25. Steingart A, Hachinski VC, Lau C, Fox AJ, Diaz F, Cape R, et al. Cognitive and neurologic findings in subjects with diffuse white matter lucencies on computed tomographic scan (leuko-araiosis). Arch Neurol 1987;44:32–35.
26. Caplan LR, Schoene WC. Clinical features of subcortical arteriosclerotic encephalopathy (Binswanger disease). Neurology 1978;28:1206–1215.
27. Rosenberg GA, Kornfeld M, Stowing J, Bicknell JM. Subcortical arteriosclerotic encephalopathy (Binswanger): computerized tomography. Neurology 1979;29:1102–1106.
28. Braffman BH, Zimmerman RA, Trojanowski JQ, Gonatas NK, Hickey WF, Schlaepfer WW. Brain MR pathologic correlation with gross and histopathology. I. Lacunar infarction and Vir-chow-Robin spaces. AJNR 1988;9:621–628.
29. Braffman BH, Zimmerman RA, Trojanowski JQ, Gonatas NK, Hickey WF, Schlaepfer WW. Brain MR pathologic correlation with gross and histopathology. 2. Hyperintense white-matter foci in the elderly. AJNR 1988;9:629–636.
30. Marshall VG, Bradley WG Jr, Marshall CE, Bhoopat T, Rhodes RH. Deep white matter infarction: correlation of MR imaging and histopathologic findings. Radiology 1988;167:517–522.