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Volumn 30, Issue 51, 1989, Pages 7257-7260

Iminoheptitols as glycosidase inhibitors: Synthesis of, and mannosidase and fucosidase inhibition by, α-homomannojirimycin and 6-epi-homomannojirimycin

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXYMANNONOJIRIMYCIN; 6 EPI ALPHA HOMOMANNOJIRIMYCIN; ALPHA HOMOMANNOJIRIMYCIN; ALPHA LEVO FUCOSIDASE; ALPHA MANNOSIDASE; UNCLASSIFIED DRUG;

EID: 0024792416     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(01)93952-8     Document Type: Article
Times cited : (39)

References (20)
  • 6
    • 84918625246 scopus 로고    scopus 로고
    • Winchester, B., Barker, C., Baines, S., Jacob, G., Namgoong, S.K., Fleet, G.W.J., Biochem. J., in press
  • 11
    • 84918620192 scopus 로고    scopus 로고
    • The respective systematic names for α-homomannojirimycin (6) and 6-epi-α-homomannojirimycin (8) are 2,6-dideoxy-2,6-imino-D-glycero-D-talo-heptitol and 2,6-dideoxy-2,6-imino-L-glycero-D-talo-heptitol.
  • 12
    • 84918637395 scopus 로고    scopus 로고
    • Bruce, I., Fleet, G.W.J., Girdhar, A., Haraldsson, M., Peach, J.M., Watkin, D.J., Tetrahedron, in press
  • 13
    • 84918626136 scopus 로고    scopus 로고
    • Physical data for all new compounds reported in this paper was consistent with the structures proposed and satisfactory microanalytical data (CHN) was obtained for the following compounds: (6) [as the hydrochloride], (11) to (19) inclusive.
  • 14
    • 85099488509 scopus 로고    scopus 로고
    • 2O): δ 54.6 and 56.0(2 × d, C-2 and C-6), 62.1(two overlapping t, C-1 and C-7), 66.8, 70.1 and 71.7 (3 × d, C-3, C-4 and C-5).
  • 15
    • 85099488824 scopus 로고    scopus 로고
    • 2O): δ 56.1 and 56.4(2 × d, C-2 and C-6), 58.3 and 59.1 (2 × t, C-1 and C-7), 63.5, 67.4 and 69.4(3 × d, C-3, C-4 and C-5).
  • 19
    • 85099488329 scopus 로고    scopus 로고
    • 2O): δ 56.2 and 59.0(2 × d, C-2 and C-6), 59.6 and 61.3(2 × t, C-1 and C-7), 68.9, 69.4 and 72.2 (3 × d, C-3, C-4 and C-5).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.