Lack of correlation between radiosensitivity and inhibition of DNA synthesis in hybrids (a-t × hela)

International Journal of Radiation Biology

Volumn 56, Issue 6, 1989, Pages 863-867

  Komatsu, K ^a   Okumura, Y ^b   Kodama, S ^a   Yoshida, M ^a   Miller, R C ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Radiological Research Laboratories College of Physicians and Surgeons of Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CULTURE; CYTOLOGY; DNA SYNTHESIS INHIBITION; HUMAN; HYBRID CELL; PRIORITY JOURNAL; RADIOSENSITIVITY;

ATAXIA TELANGIECTASIA; CELL SURVIVAL; COMPARATIVE STUDY; DNA; DOSE-RESPONSE RELATIONSHIP, RADIATION; HELA CELLS; HUMAN; HYBRID CELLS; IN VITRO; PHENOTYPE; RADIATION TOLERANCE; SUPPORT, NON-U.S. GOV'T;

EID: 0024788480     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553008914552331     Document Type: Article

References (8)

1. Gene dosage and complementation analysis of ataxia telangiectasia lymphoblastoid cell lines assayed by induced chromosome aberrations
2. Localization of an ataxia-telangiectasia gene to chromosome 11 q 22–23
3. Genetic heterogeneity in ataxia-telangiectasia studied by cell fusion
4. Suppression of tumorigenecity in somatic cell hybrids
5. DNA polymorphisms indicate loss of heterozygosity for chromosome 11 of D98AH2 cells
6. A derivative of an ataxia-telangiectasia (A-T) cell line with normal radiosensitivity but A-T-like inhibition of DNA synthesis
7. Ataxia-telangiectasia cell extracts confer radioresistant DNA synthesis on control cells
8. Complementation of the defects in DNA synthesis in irradiated and unirradiated ataxia telangiectasia cells