Antioxidant functions of carotenoids

Free Radical Biology and Medicine

Volumn 7, Issue 6, 1989, Pages 617-635

  Krinsky, Norman I ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Antioxidants; Autoxidation; Carotenoid epoxides; Carotenoids; Free radicals; Lipid peroxidation; Lipoxidases; Singlet oxygen

Indexed keywords

ANTIOXIDANT; CAROTENOID; FREE RADICAL; XANTHOPHYLL; ZEAXANTHIN;

HUMAN; LIPID PEROXIDATION; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMAL; ANTIOXIDANTS; CAROTENOIDS; FREE RADICALS; HUMAN; LIPID PEROXIDATION; MOLECULAR STRUCTURE; OXIDOREDUCTASES; SUPPORT, U.S. GOV'T, P.H.S.;

ALGAE; ANIMALIA;

EID: 0024784639     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-5849(89)90143-3     Document Type: Review

References (130)

1. Dietary intake of carotenes and the carotene gap
2. Function
3. Photobiology of carotenoid protection
4. Non-photosynthetic function of carotenoids
5. Carotenoid protection against oxidation
6. β-carotene: An unusual type of lipid antioxidant
7. Mechanisms of inactivation of oxygen species by carotenoids
8. Can dietary β-carotene materially reduce human cancer rates?
9. Evidence for the role of carotenes in preventive health
10. Carotenoids as chemopreventive agents
11. Chemistry of singlet oxygen. VIII. Quenching by β-carotene
12. The protective function of carotenoid pigments
13. Quenching of singlet oxygen
14. Biological roles of singlet oxygen
15. Chemistry of singlet oxygen. X. Carotenoid quenching parallels biological protection
16. Carotenoid chromophore length and protection against photosensitization
17. The production of superoxide radical during the decomposition of potassium peroxochromate (V)
18. The interaction of oxygen and oxy-radicals with carotenoids
19. Response of platelets exposed to potassium tetraperoxochromate an extracellular source of singlet oxygen hydroxyl radicals superoxide anions and hydrogen peroxide
20. Carotenoids quench evolution of excited species in epidermis exposed to UV- (290–320 nm) light
21. Photosensitized bleaching of β-carotene with light at 632.8 nm from a continuous-wave gas laser
22. Crocetin a water soluble carotenoid monitor for singlet molecular oxygen
23. The mechanisms of the rearrangement of linoleate hydroperoxides
24. Autoxidation of polyunsaturated lipids. Factors controlling the stereochemistry of product by hydroperoxides
25. The oxidation of β-carotene in solution by oxygen
26. Spectrophotometric studies of the oxidation of fats VIII Coupled oxidation of carotene
27. The coupled oxidation of β-carotene by a linoleatelipoxidase system and by autoxidizing linoleate
28. Autoxidation of carotene and vitamin A. Influence of fat and antioxidants
29. Oxidation of β-carotene. Site of initial attack
30. Reaction of β-carotene with N-bromosuccinimide: the formation and conversions of some polyene ketones
31. Decomposition of triphenyl phosphite ozonide in the presence of spin traps
32. Spectral characteristics and configuration of some steroisomeric carotenoids including prolycopene and pro-γ-carotene
33. Sur la présence d'une oxydase des lipides ou lipoxydase dans la graine de soja, Glycine soja Lieb
34. Carotene oxidase
35. The coupled oxidation of carotene and fat by carotene oxidase
36. Unsaturated fat oxidase
37. Nonproteolytic enzymes
38. Unsaturated fat oxidase; specificity occurrance and induced oxidations
39. Soybean lipoxidase
40. Lipoxidase and the autoxidation of unsaturated fatty acids
41. Lipoxidase or unsaturated-fat oxidase
42. Plant lipoxygenases
43. Cooxidation reactions of lipoxygenase of plant systems
44. On the question of the identity of soybean “lipoxidase” and carotene oxidase
45. Lipid oxidase studies. III. The relation between carotene oxidation and the enzymic peroxidation of unsaturated fats
46. The induced reaction between methyl linoleate and bixin during oxidation by lipoxidase
47. Coupled oxidation of carotene and linoleate catalyzed by lipoxidase
48. The oxidation of β-carotene by a lipoxidase-linoleate system
49. Degradation enzymatique et autooxydative du β-carotene
50. Cooxidation of β-carotene by an isoenzyme of soybean lipoxygenase
51. Carotene-bleaching activities of lipoxygenase and heme proteins as studied by a direct spectrophotometric method
52. Bleaching of carotenoid by the enzyme lipoxygenase
53. Coupled oxidation of carotene by lipoxygenase requires two enzymes
54. Singlet oxygen production by soybean lipoxygenase isozymes
55. Singlet oxygen production by lactoperoxidase: halide dependence and quantitation of yield
56. Purification and properties of a carotene co-oxidizing lipoxygenase from peas
57. Some properties of pea lipoxygenase isoenzymes
58. Purification and characterization of a type-1 lipoxygenase from pea seeds
59. Identifizierung von lipoxigenase-isoenzymen als carotinoxidasen
60. The enzymic destruction of carotenoids by isolated chloroplasts
61. Co-oxidation of carotene and crocin by soybean lipoxygenase isoenzymes
62. Co-oxydation of a carotenoid by the enzyme lipoxygenase: influence on the formation of linoleic acid hydroperoxides
63. HPLC analysis of all positional isomers of the monohydroperoxides formed by soybean lipoxygenases during oxidation of linoleic acid
64. Co-oxydation von β-carotin und canthaxanthin durchgereinigte lipoxygenasen aus sojbohnen
65. Co-oxidation of carotenes requires one soybean lipoxygenase isoenzyme
66. Pigment bleaching, carbonyl production and antioxidant effects during the anaerobic lipoxygenase reaction
67. Methylmercuric iodide modification of lipoxygenase-1. Effects on the anaerobic reaction and pigment bleaching
68. Pigment bleaching by soybean lipoxygenase type-2 and the effect of specific chemical modifications
69. Demonstration by EPR spectroscopy on the functional role of iron in soybean lipoxygenase-1
70. Inhibition of arachidonic acid oxidation by β-carotene, retinol and α-tocopherol
71. Carotene oxidizing factors in red pepper fruits (Capsicum annuum L) Ascorbic acid
72. Carotene oxidizing factors in red pepper fruits (Capsicum annuum L) peroxidase activity
73. Carotene oxidizing factors in red pepper fruits (Capsicum annuum L) effect of ascorbic acid and copper in a β-carotene-linoleic acid model
74. Prooxidant and antioxidant effects of ascorbic acid and metal salts in a β-carotene-linoleate model system
75. Lipid deterioration: β-carotene destruction and oxygen evolution in a system containing lactoperoxidase, hydrogen peroxide and halides
76. Initiation of lipid peroxidation by a peroxidase/hydrogen peroxide/halide system
77. Oxidation of β-carotene by bovine milk lactoperoxidase-halide-hydrogen peroxide systems
78. Lipid deterioration initiated by phagocytic cells in muscle food: β-carotene destruction by a myeloperoxidase-hydrogen peroxide-halide system
79. Oxidant membrane injury by the neutrophil myeloperoxidase system II. Injury by stimulated neutrophils and protection by lipid-soluble antioxidants
80. Ambiguity associated with the use of singlet oxygen trapping agents in myeloperoxidase-catalyzed oxidations
81. Biological reactivity of hypochlorous acid: implications for microbicidal mechanisms of leukocyte myeloperoxidase
82. Nitric-oxide myoglobin as an indicator of lipid oxidation
83. 2 activated metmyoglobin
84. A parallel study of pigment bleaching and cytochrome breakdown during aging of thylakoid membranes
85. Destruction of carotenoids in isolated chloroplasts
86. The oxidation of carotenoids by mitochondria from sugar beet leaves. I. Crocin oxidation by mitochondria
87. The oxidation of carotenoids by mitochondria from sugar beet leaves. II. Crocin oxidation by an unsaturated fat oxidase system in triton extracts of mitochondria
88. The oxidation of carotenoids by mitochondria from sugar beet leaves. III. Crocin oxidation by a peroxidase system
89. Increase in lipid-dependent carotene destruction as compared to ethylene formation and chlorophyllase activity following mixed infection of sugar beet (Beta-vulgaris, L.) with beet yellows virus and beet mild yellowing virus
90. Free radicals and singlet oxygen scavengers: reaction of a peroxy-radical with β-carotene, diphenyl furan and 1,4-diazobicyclo(2,2,2)-octane
91. Antioxidants in relation to lipid peroxidation
92. Organic oxygen radicals in biology: generation and reactions
93. Generation and reactivities of various types of oxygen radicals
94. Radical intermediates involved in the bleaching of the carotenoid crocin. Hydroxyl radicals, superoxide anions and hydrated electrons
95. The bleaching of crocin by oxygen radicals
96. Inhibition of the bleaching of the carotenoid crocin A rapid test for quantifying antioxidant activity
97. Membrane antioxidants
98. Superoxide, hydrogen peroxide, and singlet oxygen in lipid peroxidation by a xanthine oxidase system
99. Protective action of carotenoid pigments against photodynamic damage to liposomes
100. Carotenoid pigments: multiple mechanisms for coping with the stress of photosensitized oxidations
101. Red blood cells lysis induced by a product of singlet oxygen and cholesterol
102. Influence of dietary β-carotene on the stability of mitochondrial retinol, α-tocopherol and fatty acids during NADPH-induced peroxidation
103. Studies on the role of reactive oxygen species in mediating lipid peroxide formation in epidermal microsomes of rat skin
104. Antioxidant behavior of ubiquinone and β-carotene incorporated in model membranes
105. Bilirubin is an antioxidant of possible physiological importance
106. Inhibition of adriamycin-promoted microsomal lipid peroxidation by β-carotene, α-tocopherol and retinal at high and low oxygen partial pressures
107. The transport of vitamin a and carotenoids in human plasma
108. Contributions of carotenoids to the optical activity of human serum low-density lipoprotein
109. Studies on the absorption of beta-carotene and the distribution of total carotenoid in human serum lipoproteins after oral administration
110. Uptake of irradiated human low density lipoprotein by cultured Chinese hamster V79 cells
111. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
112. Comparison of the efficiencies of several natural and synthetic antioxidants in aqueous sodium dodecyl sulfate micelle solutions
113. The effect of vitamin C on in vivo lipid peroxidation in guinea pigs as measured by pentane and ethane production
114. The role of carotenoids and vitamin A in encephalomalacia
115. Dietary canthaxanthin as a protective agent against lipid peroxidation in biomembranes
116. Lipid peroxide α-tocopherol and retinoid levels in plasma and liver iof rats fed diets containing β-carotene and 13-cis-retinoic acid
117. Effects of β-carotene and retinyl palmitate on corn oil-induced superoxide dismutase and catalase in rats
118. Activation of catalase and other enzymes by corn oil intake
119. The effect of dietary vegetable fats on the growth of morris hepatoma 7800
120. Effects of anioxidants on oxidant-induced sister chromatid exchange formation
121. The role of carotenoids in preventing oxidative damage in the pigmented yeast. Rhodotorula mucilaginosa
122. Singlet oxygen-initiated photoxidation of unsaturated fatty acid esters and inhibitory effects of tocopherols and β-carotene
123. Inhibitory effects of tocopherols and β-carotene on singlet oxygen-initiated photoxidation of methyl linoleate and soybean oil
124. Use of a gas chromatographic reactor to study lipid photoxidation
125. Prüfing der antioxidansaktivität mit azo-bis-isobutyronitril und β-carotin
126. Oxidation of β-carotene by hydroperoxides
127. Antioxidant action of carotenoids