Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.

Proceedings of the National Academy of Sciences of the United States of America

Volumn 86, Issue 10, 1989, Pages 3559-3563

  Lynn, R M ^a   Bjornsti, M A ^a   Caron, P R ^a   Wang, J C ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; DNA TOPOISOMERASE; TYROSINE;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; COMPARATIVE STUDY; DNA SUPERCOILING; ENZYMOLOGY; FUNGAL GENE; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SACCHAROMYCES CEREVISIAE; ULTRASTRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; DNA MUTATIONAL ANALYSIS; DNA TOPOISOMERASES, TYPE I; DNA, SUPERHELICAL; DNA-BINDING PROTEINS; GENES, FUNGAL; MOLECULAR SEQUENCE DATA; SACCHAROMYCES CEREVISIAE; TYROSINE;

EID: 0024670218     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.86.10.3559     Document Type: Article

References (0)