Gastric emptying and small and large bowel transit of non-disintegrating tablets in fasted subjects

International Journal of Pharmaceutics

Volumn 52, Issue 1, 1989, Pages 1-10

  Khosla, R ^a   Davis, S S ^a  

^a Department of Pharmaceutical Sciences University of Nottingham NottinghamUK ^*

Author keywords

Colonic transit; Gastrointestinal transit; Non disintegrating tablet; Scintigraphy

Indexed keywords

ETHYL CELLULOSE;

DRUG FORMULATION; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL; STOMACH EMPTYING; TABLET DISINTEGRATION;

EID: 0024605050     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(89)90082-3     Document Type: Article

References (20)

1. The interdigestive myoelectric complex of the stomach and small bowel of dogs
2. Studies on the gastrointestinal transit of dosage forms in human subjects using the technique of gamma scintigraphy
3. The transit of pharmaceutical dosage forms through the small intestine
4. The in vivo evaluation of an osmotic device (Osmet) using gamma scintigraphy
5. Relationship between the rate of appearance of Oxprenolol in the systemic circulation and the location of a 16/260 Oxprenolol Oros drug delivery system within the gastrointestinal tract as de- termined by scintigraphy
6. Colonic release of 5-ASA from an oral preparation in active ulcerative colitis
7. Investigating the gastrointestinal transit of controlled release mini-matrices using gamma scintigraphy
8. Validity of the geometric mean correction in the quantification of whole bowel transit
9. Drug delivery to the proximal colon
10. Spreading characteristics of proprietary rectal steroid preparations
11. Controlled entry of orally administered drugs physiological considerations
12. Gastrointestinal transit of Oros drug delivery systems in healthy volunteers. A short report
13. Gastrointestinal Transit of Dosage Forms
14. Flow across the canine ileocolonic junction role of the ileocolonic sphincter
15. Coating of oral beclomethasone diproprionate capsules with cellulose acetate phthalate enhances delivery of topically active anti-inflammatory drug to the terminal colon
16. Evaluation of the effect of food and specific gravity of tablets on gastric retention time
17. Emptying of the terminal ileum in intact humans
18. Techniques and errors in scintigraphic measurement of gastric emptying
19. The spreading of foam and solution enemas