The current and potential role of hyperthermia in radiotherapy

International Journal of Radiation Oncology, Biology, Physics

Volumn 16, Issue 3, 1989, Pages 535-549

  Overgaard, Jens ^a  

^a DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

Biological rationale; Clinical studies; Clinical trials; Hyperthermia; Radiotherapy

Indexed keywords

CANCER; CLINICAL TRIAL; HUMAN; HYPERTHERMIA; METHODOLOGY; PRIORITY JOURNAL; RADIOTHERAPY; REVIEW;

COMBINED MODALITY THERAPY; HUMAN; HYPERTHERMIA, INDUCED; NEOPLASMS;

EID: 0024602937     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/0360-3016(89)90470-7     Document Type: Article

References (131)

1. Multi-institutional studies on hyperthermia using an 8MHz radiofrequency capacitive heating device (Thermotron RF-8) in combination with radiation for cancer therapy
2. Clinical experience with microwave and radiofrequency thermotherapy in the treatment of advanced cancer
3. Randomized trial of 1 vs. 2 adjuvant hyperthermia treatments in patients with superficial metastases
4. Radiation therapy with or without primary limited surgery for operable breast cancer: a 20-year experience at the Marseilles Cancer Institute
5. Tumour response to heat and radiation: Prognostic variables in the treatment of neck node metastases from head and neck cancer
6. Radiotherapy and hyperthermia. Analysis of clinical results and identification of prognostic variables
7. Biological rationale for optimal scheduling of heat and ionizing radiation: Clinical results on neck node metastases
8. Problem of sequence and fractionation in the clinical application of combined heat and radiation
9. Hyperthermia trials
10. Radiotherapy alone in breast cancer. I. Analysis of tumor parameters, tumor dose and local control: the experience of the Gustave-Roussy Institute and the Princess Margaret Hospital
11. A 500 KHz localized current field hyperthermia system for use with opthalmic plaque radiotherapy
12. A Hyperthermia System Using a New Type of Inductive Applicator
13. Size/dose relationships and local control of oro- and hypopharyngeal cancer treated by radiotherapy
14. Relation between time-dose and local control of operable breast cancer treated by tumorectomy and radiotherapy or by radical radiotherapy alone
15. Analysis of failures following local treatment of isolated local-regional recurrence of breast cancer
16. Analysis of failures after definitive irradiation for edipermoid carcinoma of the nasopharynx
17. Potentialisation de la radiothérapie locale. A propos de 90 tumeurs superficielles comparables (Abstract)
18. Hyperthermia in combination with radiotherapy for middle and late stage bladder carcinoma
19. Résultats. Thérapeutiques non mutilantes des cancereuses du sein
20. Combination of interstitial hyperthermia and brachytherapy. Our resistive diathermy experience (Abstract)
21. Locally recurrent carcinoma of the breast. Results of radiation therapy
22. Combined ultrasound and radiation therapy treatment of human superficial tumors
23. Interstitial thermoradiotherapy: a technical and clinical study of 29 implantations performed at the Institut Gustave-Roussy
24. Thermoradiotherapy in the management of carcinoma cervix (III B): a controlled clinical study
25. Cell biology of hyperthermia and radiation
26. Estimation of therapeutic gain in clinical trials involving hyperthermia and radiotherapy
27. Clinical application of thermal isoeffect dose
28. An assessment of local hyperthermia in clinical practice
29. A retrospective study of irradiation versus combined irradiation plus hyperthermia in recurrent head and neck cancers (Abstract Bg-1)
30. Thermoradiotherapy of malignant melanoma
31. Interstitial thermoradiotherapy in treatment of malignant tumours
32. Clinical hyperthermia ot studies, Thomas Jefferson University Hospital, results of 42.5°C adjuvant to irradiation
33. Studies relevant to a means of quantifying the effects of hyperthermia
34. Hyperthermia in the treatment of cancer
35. Physics and technology of hyperthermia
36. The relationship between heating time and temperature: its relevance to clinical hyperthermia
37. Combined treatment of radiotherapy and local hyperthermia using 8 MHz RF-wave for ad vanced carcinoma of the breast
38. Interstitial hyperthermia using implanted electrodes: A multicentric program of technical evaluation and clinical trials over 96 patients
39. Thermal dose and time-temperature factors for biological responses to heat shock
40. Local control of breast cancer with tumorectomy plus radiotherapy or radiotherapy alone
41. Experience in the use of thermoradiotherapy of malignant tumors (In Russian)
42. Simultaneous intraoperative radiation therapy and intraoperative interstitial hyperthermia for unresectable adenocarcinoma of the pancreas
43. Chestwall recurrences of breast cancer: Results of combined treatment with radiation and hyperthermia
44. Combined treatment with radiation and hyperthermia in metastatic malignant melanoma
45. Clinical results of radiofrequency hyperthermia combined with radiation in the treatment of radioresistant cancers
46. Clinical hyperthermia: medical aspects
47. Thermoradiotherapy of primary breast carcinoma
48. The combination of radiotherapy with hyperthermia in protocolized clinical studies
49. Advanced stage IIIB cancer of the cervix treatment by hyperthermia and radiation
50. Hyperthermia and radiation in the treatment of superficial malignancy: an analysis of treatment parameters, response and toxicity
51. Clinical results of thermoradiotherapy for breast cancer
52. A pilot study to investigate skin and tumor thermal enhancement ratios of 41.5–42.0°C hyperthermia with radiation
53. Site and disease selection for hyperthermic clinical trials
54. Prognostic factors predicting tumor response (TR), local control (LC), and complications (C) in patients treated on randomized protocols with radiation therapy (XRT) and either 2 or 6 hyperthermia treatments (HT) (Abstract Bg3)
55. Clinical and biological studies of localized hyperthermia
56. Combination hyperthermia and radiation therapy for malignant melanoma
57. Clinical study of the sequence of combined hyperthermia and radiation therapy of malignant melanoma
58. Radiofrequency hyperthermia for clinical cancer therapy
59. Combination hyperthermia and radiation therapy for cutaneous malignant melanoma
60. Local tumor hyperthermia in combination with radiation therapy. 1. Malignant cutaneous lesions
61. Local hyperthermia and radiation for advanced superficial tumor
62. Combination therapy of radiofrequency hyperthermia and radiation on advanced bladder cancer
63. A microwave heating technique for the hyperthermic treatment of tumours in the eye, especially retinoblastoma
64. Interstitial thermoradiotherapy for recurrent or persistent tumors
65. Effect of hyperthermia combined with radiation in the treatment of superficial malignant lesion in 90 patients
66. Clinical evaluation of combined radiotherapy and thermotherapy on carcinoma of the breast (in Chinese)
67. Low dose radiotherapy in superficial human tumors with evaluation of prognostic factors for tumour response
68. Microwave-induced hyperthermia and radiotherapy in human superficial tumours. Clinical results with a com parative study of combined treatment versus radiotherapy alone
69. Preliminary technical, experimental and clinical results of the use of the HPLR 27 sys tem for the treatment of deep-seated tumours by hyperthermia
70. Analysis of time-dose factors in clinically positive neck nodes treated with irradiation alone in squamous cell carcinoma of the head and neck
71. The clinical efficacy of localized hyperthermia
72. Hyperthermia in therapy of cancer patients (in Russian)
73. Eine neue Behandlungsmethode bösartiger Geschwülste
74. Therapeutische Erfahrungen an 100 mit Kombination von Röntgenstrahlen and Hochfrequenz, resp. Diathermie behandelten bösartigen Neubildungen
75. Combined radiation therapy and hyperthermia for advanced head and neck cancer: preliminary reports
76. Preoperative hyperthermia (HT) and radiotherapy (RT) for extremity sarcoma: initial results (Abstract Bb7)
77. A review of the University of Arizona human clinical hyperthermia experience
78. Effect of hyperthermia on malignant cells in vivo. A review and hypothesis
79. Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo
80. Fractionated radiation and hyperthermia. Experimental and clinical studies
81. Hyperthermic modification of the radiation response in solid tumors
82. History and heritage-an introduction
83. The design of clinical trials in hyperthermic oncology
84. The role of radiotherapy in recurrent and metastatic malignant melanoma: a clinical radiobiological study
85. Clinical hyperthermia-an update
86. Hyperthermia as an adjuvant to radiotherapy. Review of the randomized multicenter studies of the European Society for Hyperthermic Oncology
87. Some problems related to the clinical use of thermal isoeffect doses
88. The design of clinical trials in hyperthermic oncology
89. The importance of thermotolerance for the clinical treatment with hyperthermia
90. Biological basis for rational design of clinical treatment with combined hyperthermi and radiation
91. Hyperthermia as an adjuvant to radiotherapy in the treatment of malignant melanoma
92. Is there a role for hyperthermia in gastrointestinal tract cancer
93. Clinical experience with local hyperthermia using a 144 MHz inductive heating system with a single applicator
94. Quality assurance problems in clinical hyperthermia and its impact on therapeutic outcome. A report by the Radiation Therapy Oncology Group
95. Local microwave hyperthermia and irradiation in cancer therapy: Preliminary observations and directions for future clinical trials
96. Irradiation alone or combined with hyperthermia in the treatment of recurrent carcinoma of the breast in the chest wall. A nonrandomized comparison
97. Carcinoma of the tonsillar fossa. Significance of dose of irradiation and volume treated in the control or the primary tumor and metastatic neck nodes
98. Regional hyperthermia with BSD-1000 annular phased array in the management of recurrent deep seated malignant tumors
99. Interstitial hyperthermia for recurrent malignancies
100. Proton beam irradiation and hyperthermia. Effects on experimental choriodal melanoma
101. Locally advanced breast cancer treated initially by external radiation (250 kV X-rays)
102. Thermal isoeffect dose: addressing the problem of thermotolerance
103. Thermal dose determination in cancer therapy
104. Regional hyperthermia for clinically advanced deep-seated pelvic malignancy
105. The use of hyperthermia in oncology (in Russian)
106. Treatment of retinoblastoma by radiotherapy combined with hyperthermia (Abstract)
107. Hyperthermia in combination with radiotherapy: A review of five years experience in the treatment of superficial tumors
108. Local hyperthermia in combination with definitive radiotherapy: Increased tumor clearance, reduced recurrence rate in extended follow-up
109. Local microwave hyperthermia for superficial chestwall recurrences (Abstract Bg-7)
110. Correlation between hyperthermia and large dose per fraction in treatment of malignant melanoma (Abstract)
111. Regional hyperthermia for deep-seated malignancies using the BSD annular array
112. Matched-pair analysis of response to local hyperthermia and megavoltage electron therapy for su perficial human tumors
113. Thermal enhancement of radiation response: A growth delay study on superficial human tumour metastases
114. The use of local hyperthermia for therapy of cancer patients (in Russian)
115. Microwave-induced local hyperthermia in combination with radiotherapy of human malignant tumors
116. Clinical evaluation of combined hyperthermia and radiation therapy of superficial malignant tumors
117. Kinetics of thermotolerance in normal and tumor tissues: a review
118. 3 (TNM-UICC) metastatic neck nodes managed by combined radiation therapy and hyperthermia: clinical results and analysis of treatment parameters
119. Radical radiation alone versus radical radiation plus microwave hyperthermia for N3 (TNM-UICC) neck nodes: a prospective randomized clinical trial
120. Retrospective analysis of the response of tumors in patients treated with a combination of radiotherapy and hyperthermia
121. Clinically derived dose effect relationship for hyperthermia with low dose radiotherapy
122. Physiological effects of hyperthermia
123. Interstitial implant with interstitial hyperthermia
124. Primary radiation combined with hyperthermia for advanced (Stage III–IV) and inflammatory carcinoma of breast
125. A new isoeffect curve for change in dose per fraction
126. Problems in the clinical usage of thermal dose
127. Local hyperthermia for treatment of carcinoma of the prostate: a preliminary report
128. Acute and 5 years' evaluation of localized deep microwave hy perthermia in the treatment of prostatic carcinoma (Abstract)