The Metabolic Consequences of the Correction of Acidosis in Uraemia

Nephrology Dialysis Transplantation

Volumn 4, Issue 2, 1989, Pages 92-95

  Jenkins, D ^a   Burton, P R ^a   Bennett, S E ^a   Baker, F ^a   Walls, J ^a,b  

^a LEICESTER GENERAL HOSPITAL   (United Kingdom)

^b NONE

Author keywords

Acidosis; Bicarbonate supplementation; Uraemia

Indexed keywords

BICARBONATE; URIC ACID;

ADULT; CHRONIC KIDNEY FAILURE; CLINICAL ARTICLE; HUMAN; METABOLIC ACIDOSIS; PRIORITY JOURNAL; UREMIA;

ACIDOSIS, RENAL TUBULAR; ADULT; BICARBONATES; BLOOD GLUCOSE; BLOOD PROTEINS; FEMALE; HUMAN; INSULIN; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGE; SODIUM; SODIUM BICARBONATE; SUPPORT, NON-U.S. GOV'T; UREA; UREMIA;

EID: 0024600282     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/oxfordjournals.ndt.a091849     Document Type: Article

References (14)

1. Oliver DO, Wing AJ. Chronic renal failure, dialysis and transplantation. In: Oxford Textbook of Medicine. 2nd edit. New York, Oxford University Press, 1987
2. Chan MK, Varghese Z, Moorhead JF. Lipid abnormalities in uremia, dialysis and transplantation. Kidney Int 1981; 19: 625-637
3. DeFronzo RA, Alvestrand A. Glucose intolerance in uremia; Site and mechanism. Am J Clin Nutr 1980; 33: 1438-1445
4. Ritz E. Pathogenesis of uremia. Nephrology II. (Proceedings of the IXth International Congress of Nephrology, USA.) New York, Springer-Verlag
5. Lyon DM, Dunlop DM, Stewart CP. The alkaline treatment of chronic nephritis. Lancet 1931; 2: 1009-1013
6. May RC, Kelly RA, Mitch WE. Metabolic acidosis stimulates protein degradation in rat muscle by a glucocorticoid-dependent mechanism. J Clin Invest 1986; 77:614-621
7. May RA, Kelly RA, Mitch WE. Mechanisms for defects in muscle protein metabolism in rats with chronic uremia. Influence of metabolic acidosis. J Clin Invest 1987; 79: 1099-1103
8. Blom van Assendelft PM, Dorhout Mees EJ. Urea metabolism in patients with chronic renal failure: influence of sodium bicarbonate or sodium chloride administration. Metabolism 1970; 19:1053-1063
9. Papadoyannakis NJ, Stefanides CJ, McGeown M. The effect of the correction of metabolic acidosis on nitrogen and potassium balance of patients with chronic renal failure. Am J Clin Nutr 1984; 40: 623-627
10. Fine RN, Strauss J, Donnel GN. Hyperuricemia in glycogen storage disease type 1. AmJDis Child 1966; 112: 572
11. Roe TF, Kogut MD. The pathogenesis of hyperuricemia in GSD type I. Pediat Res 1977; 11: 664-669
12. Ginsberg HN. Effect of treatment on insulin resistance in subjects with ketosis-prone diabetes mellitus. Clin Res 1976; 24: 361A
13. De Fronzo RA, Beckles AD. Glucose intolerance following chronic metabolic acidosis in man. Am J Physiol 1979; 236: E328-334
14. Weinberger MH. Sodium chloride and blood pressure. N Engl J Med 1987; 317: 1084-1085