Different mutations responsible for the elevated sister-chromatid exchange frequencies in Bloom syndrome and X-irradiated B-lymphoblastoid cell lines originating from acute leukemia

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 211, Issue 2, 1989, Pages 273-278

  Shiraishi, Y ^a   Taguchi, T ^a   Ozawa, M ^a   Bamezai, R ^b  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b BANARAS HINDU UNIVERSITY   (India)

Author keywords

Bloom syndrome cells; Bromodeoxyridine; Cell hybridization; Co cultivation; Mutant cells; SCE level; Thymidylate synthetase

Indexed keywords

THYMIDYLATE SYNTHASE;

ACUTE LEUKEMIA; BLOOM SYNDROME; CELL CULTURE; CELL LINE; CYTOLOGY; HEREDITY; HUMAN; HUMAN CELL; HYBRID CELL; LYMPHOBLASTOID CELL; PRIORITY JOURNAL; SISTER CHROMATID EXCHANGE; X RAY;

B-LYMPHOCYTES; BLOOM SYNDROME; CELL FUSION; CELL LINE; CELLS, CULTURED; HUMAN; LEUKEMIA; MUTATION; SISTER CHROMATID EXCHANGE; SUPPORT, NON-U.S. GOV'T; THYMIDYLATE SYNTHASE; TUMOR CELLS, CULTURED; X-RAYS;

EID: 0024597969     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(89)90010-9     Document Type: Article

References (13)

1. Direct implantation and serial transplantation of human acute lymphoblastic leukemia in hamster, SB-2
2. Cell cycle progression and SCE rate of Bloom syndrome cells with/without co-cultivation in the presence/absence of normal cells
3. 3H
4. Mutagenesis to aminopterin resistance in cultured hamster cells
5. Hybridization with human cells corrects the elevated SCE frequency and BrdU hypersensitivity of hamster cell line EM9
6. Different mutations are responsible for the elevated sister-chromatid exchange frequencies characteristic of Bloom's syndrome and hamster EM9 cells
7. Increased system chromatid exchange in bone marrow and blood cells from Bloom's syndrome
8. Normalization by cell fusion of sister chromatid exchange in Bloom syndrome lymphocytes
9. Analysis of single and twin sister chromatid exchanges in endoreduplicated normal and Bloom syndrome B-lymphoid cells
10. Establishment of B-lymphoid cell lines retaining cytogenetic characteristics of Bloom syndrome
11. Analyses of bromodeoxyuridine-associated sister chromatid exchanges (SCEs) in bloom syndrome based on cell fusion: single and twin SCEs in endoreduplication
12. Dimorphism of sister chromatid exchange in Bloom syndrome B- and T-cell lines transformed with Epstein-Barr and adult T-cell leukemia viruses
13. Increased sister-chromatid exchanges (SCEs) and chromosomal fragilities by BrdU in a human mutant B-lymphoblastoid cell line