The effect of particle size distribution on dissolution rate and oral absorption

International Journal of Pharmaceutics

Volumn 51, Issue 1, 1989, Pages 9-17

  Hintz, Rebecca J ^a   Johnson, Kevin C ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Computer simulation; Dissolution rate; Oral absorption; Particle size distribution

Indexed keywords

DODECYL SULFATE SODIUM; LACTOSE; MAGNESIUM STEARATE; STARCH;

COMPUTER; COMPUTER ANALYSIS; DRUG ABSORPTION; DRUG CAPSULE; DRUG SOLUBILITY; METHODOLOGY; NONHUMAN; PARTICLE SIZE; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL;

EID: 0024596954     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(89)90069-0     Document Type: Article

References (11)

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8. Dissolution rates of finely divided drug powders. I. Effect of a distribution of particle sizes in a diffusion-controlled process
9. Population balance modeling of the dissolution of polydisperse solids: rate limiting regimes
10. The rate of solution of solid substances in their own solutions
11. Evaporation from drops. I