Inhibition of heat shock (stress) protein induction by deuterium oxide and glycerol: Additional support for the abnormal protein hypothesis of induction

Journal of Cellular Physiology

Volumn 139, Issue 2, 1989, Pages 219-228

  Edington, Brent V ^a,b   Whelan, Sandra A ^a,c   Hightower, Lawrence E ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b PLANT BIOLOGY DIVISION   (United States)

^c BRIDGEWATER STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM OXIDE; GLYCEROL; HEAT SHOCK PROTEIN; RADIOISOTOPE;

ANIMAL CELL; CELL CULTURE; CHICKEN; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA TRANSCRIPTION;

ANIMAL; BLOTTING, NORTHERN; CELLS, CULTURED; DEUTERIUM; DEUTERIUM OXIDE; GENE EXPRESSION REGULATION; GLYCEROL; HEAT; HEAT-SHOCK PROTEINS; NUCLEIC ACID HYBRIDIZATION; RNA; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION, GENETIC; WATER;

EID: 0024596704     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.1041390202     Document Type: Article

References (74)

1. Key features of heat shock regulatory elements
2. Abnormal proteins serve as eucaryotic stress signals and trigger the activation of heat shock genes
3. Synthesis of heat‐shock proteins by cells undergoing myogenesis
4. 2O treatment
5. Increased thermal stability of proteins in the presence of sugars and polyols
6. Heat shock‐induced translational control of hsp70 and globin synthesis in chicken reticulocytes
7. Translational activation of maternal mRNA encoding the heat‐shock protein hsp90 during sea urchin embryogenesis
8. Mechanisms of heat shock gene activation in higher eukaryotes
9. Ubiquitin is a heat shock protein in chicken embryo fibroblasts
10. Microinjection of ubiquitin: Changes in protein degradation in HeLa cells subjected to heat‐shock
11. Cloning of the chick hsp90 cDNA in an expression vector
12. Number and evolutionary conservation of α‐ and β‐tublin and cytoplasmic β‐ and ∂‐actin genes using specific cloned cDNA probes
13. The heat shock response is self‐regulated at both the transcriptional and posttranscriptional levels
14. Glycerolization of Chinese hamster cells in monolayer culture
15. Addendum: A technique for radiolabeling DNA restriction endonuclease fragments to a high specific activity
16. Isolation of mutations that act in trans to alter expression from a yeast hsp70 promoter
17. Thermolability of ubiquitin‐activating enzyme from the mammalian cell cycle mutant ts85
18. The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses
19. 2O. I. Cell survival nd the temperature shift
20. Increased thermal stability of collagen in the presence of sugars and polyols
21. The effects of polyhydric and monohydric alcohols on the heat‐induced reversible denaturation of lysozyme and ribonuclease
22. 2O
23. Solvent isotope effects on the structure and function of mitochondrial membranes in aqueous media
24. Interaction of mono‐ and polyhydroxyl alcohols with hyperthermia in CHO cells
25. Heat protectors of mammalian cells
26. Protection against heat‐induced cell killing by polyols in vitro
27. Protection by glycerol in vitro
28. Molecular cloning of sequences encoding the human heat‐shock proteins and their expression during hyperthermia
29. Cultured animal cells exposed to amino acid analogues or puromycin rapidly synthesize several polypeptides
30. Stress responses in avian and mammalian cells
31. Cellular responses to stress: Comparison of a family of 71‐73 kilodalton proteins rapidly synthesized in rat tissue slices and canavanine‐treated cells in culture
32. Actin gene mutations in Drosophila; heat shock activation in the indirect flight muscles
33. Induction of four proteins in chick embryo cells by sodium arsenite
34. The effect of amino acid analogues and heat shock on gene expression in chicken embryo fibroblasts
35. Heat‐inducible human factor that binds to a human hsp70 promoter
36. Leader length and secondary structure modulate mRNA function under conditions of stress
37. 2O
38. Effects of sugar solutions on the activity coefficients of aromatic amino acids and their N‐acetyl ethyl esters
39. Heat shock proteins and cell thermotolerance
40. Effect of cycloheximide or puromycin on induction of thermotolerance by sodium arsenite in Chinese hamster ovary cells: Involvement of heat shock proteins
41. Induction of heat shock proteins in Chinese hamster overy cells and development of thermotolerance by intermediate concentrations of puromycin
42. RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination
43. Thermal analysis of CHL V79 cells using differential scanning calorimetry: Implications for hyperthermic cell killing and the heat shock response
44. Induction of thermotolerance and enhanced heat shock protein synthesis in Chinese hamster fibroblasts by sodium arsenite and by ethanol
45. 2O. II. Thermotolerance and the specific inhibition of development
46. Thermotolerance in mammalian systems: A review
47. 2O
48. Protection of heat induced cytotoxicity by glycerol
49. Relationship between hyperthermic cell killing and protein denaturation by alcohols
50. Deuterium oxide protects against hyperthermic cell death: Evidence for role of interfacial water
51. Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct
52. Organization, nucleotide sequence, and transcription of the chicken hsp70 gene
53. A major collagenbinding protein of chick embryo fibroblasts is a novel heat shock protein
54. Effect of heat shock on protein degradation in mammalian cells: Involvement of the ubiquitin system
55. A Drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp70 gene
56. Mutations that induce the heat shock response of Drosophila
57. A regulatory upstream promoter element in the Drosophila hsp70 heat‐shock gene
58. 2O of the temperature‐tolerance of adult Drosophila
59. The effect of deuterium oxide on thermal sensitivity and thermal tolerance in cultured Chinese hamster V79 cells
60. The RNA polymerase II molecule at the 5′ end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged
61. Yeast heat shock factor is an essential DNA‐binding protein that exhibits temperature‐dependent phosphorylation
62. Transcriptional activation of heat‐shock genes in eukaryotes
63. Hybridization of denatured RNA and small DNA fragments transfered to nitrocellulose
64. Massive heat‐shock polypeptide synthesis in late chicken embryos: Convenient system for study of protein synthesis in highly differentiated organisms
65. Heat shock and thermotolerance during early rat embryo development
66. Variation in sensitivity to heat shock during the cell‐cycle of Chinese hamster cells in vitro
67. Stress mRNA metabolism in canavanine‐treated chicken embryo cells
68. Effects of polyhydroxyl alcohols on protein synthesis in brain slices
69. Isolation of the gene encoding the S. cerevisiae heat shock transcriotion factor
70. The Saccharomyces and Drosophila heat shock transcription factors are identical in size and DNA binding properties
71. Purification and properties of Drosophila heat shock activator protein
72. Germline transformation used to define key features of heat‐shock response elements
73. Induction of sequence‐specific binding of Drosophila heat shock activator protein without protein synthesis