Development of Phosphonate Derivatives of Gadolinium Chelates for NMR Imaging of Calcified Soft Tissues

Journal of Medicinal Chemistry

Volumn 32, Issue 1, 1989, Pages 139-144

  Adzamli, I Kofi ^a   Gries, H ^b   Johnson, D ^a   Blau, M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BAYER PHARMA AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM CHELATE; GADOLINIUM ETHYLENEDIAMINETETRAKIS(METHYLENEPHOSPHONATE); GADOLINIUM PENTETATE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; CALCIFICATION; DRUG DISTRIBUTION; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; RAT; SOFT TISSUE; STRUCTURE ACTIVITY RELATION;

ANIMAL; BONE AND BONES; CALCINOSIS; CONTRAST MEDIA; GADOLINIUM; LIGANDS; MAGNETIC RESONANCE IMAGING; ORGANOMETALLIC COMPOUNDS; PHOSPHONIC ACIDS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; TISSUE DISTRIBUTION;

EID: 0024590567     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00121a026     Document Type: Article

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