Protein Binding of Quinolonecarboxylic Acids: I: Cinoxacin Nalidixic Acid And Pipemidic Acid1 ”

Chemical and Pharmaceutical Bulletin

Volumn 37, Issue 3, 1989, Pages 742-745

  Izumr, Taro ^a   Kitagawa, Takayasu ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

albumin; binding parameter; cinoxacin; lipophilicity; nalidixic acid; pipemidic acid; pKa; serumprotein binding; species dependence; substituent effect

Indexed keywords

ALBUMIN; CINOXACIN; GLOBULIN; NALIDIXIC ACID; OROSOMUCOID; PIPEMIDIC ACID;

ANIMAL CELL; CIRCULAR DICHROISM; DOG; DRUG PROTEIN BINDING; EQUILIBRIUM DIALYSIS; HUMAN; HUMAN CELL; NONHUMAN; NORMAL HUMAN; PH; RAT; ULTRAFILTRATION;

ANIMAL; BLOOD PROTEINS; CINOXACIN; DIALYSIS; DOGS; HUMAN; IN VITRO; NALIDIXIC ACID; NICOTINIC ACIDS; PIPEMIDIC ACID; PROTEIN BINDING; PYRIDAZINES; RATS; SPECIES SPECIFICITY;

EID: 0024583896     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.37.742     Document Type: Article

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