Potential Antitumor Agents. 57. 2-phenylquinoline-8-carboxamides as “Minimal” DNA-Intercalating Antitumor Agents with in Vivo Solid Tumor Activity

Journal of Medicinal Chemistry

Volumn 32, Issue 2, 1989, Pages 396-401

  Atwell, Graham J ^a   Baguley, Bruce C ^a   Denny, William A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

2 PHENYL 8 QUINOLINECARBOXAMIDE DERIVATIVE; N [2 (DIMETHYLAMINO)ETHYL] 2 (4 PYRIDYL) 8 QUINOLINECARBOXAMIDE; N [2 (DIMETHYLAMINO)ETHYL] 2 PHENYL 8 QUINOLINECARBOXAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; CELL CULTURE; CYTOTOXICITY; DNA BINDING; DRUG SCREENING; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; LEUKEMIA; LEUKEMIA P 388; LEWIS CARCINOMA; NONHUMAN; SOLID TUMOR;

AMIDES; ANTINEOPLASTIC AGENTS; DNA; INTERCALATING AGENTS; NEOPLASMS, EXPERIMENTAL; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T;

EID: 0024582632     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00122a018     Document Type: Article

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