Structure-Activity Study of the Actions of Camptothecin Derivatives on Mammalian Topoisomerase I: Evidence for a Specific Receptor Site and a Relation to Antitumor Activity

Cancer Research

Volumn 49, Issue 6, 1989, Pages 1465-1469

  Jaxel, Christine ^a   Kohn, Kurt W ^a   Wani, Mansukh C ^b   Wall, Monroe E ^b   Pommier, Yves ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b RTI INTERNATIONAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; CAMPTOTHECIN DERIVATIVE; DNA TOPOISOMERASE;

ANTINEOPLASTIC ACTIVITY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMAL; ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I; DNA, SUPERHELICAL; MICE; RECEPTORS, DRUG; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0024560495     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

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