-
1
-
-
0019142866
-
Increase of NAD(P)H:Quinone reductase by dietary antioxidants: Possible role in protection against carcinogenesis and toxicity
-
BENSON, A.M., HUNKELER, M.J. & TALALAY, P. (1980). Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity. Proc. Natl Acad. Sci. USA, 77, 5216.
-
(1980)
Proc. Natl Acad. Sci. USA
, vol.77
, pp. 5216
-
-
Benson, A.M.1
Hunkeler, M.J.2
Talalay, P.3
-
2
-
-
0022640856
-
Circumvention of deficient activation in mitomycin C-resistant human colonic carcinoma cells by the mitomycin C analogue BMY 25282
-
CHAKRABARTY, S., DANELS, Y.J., LONG, B.H., WILLSON, J.K.V. & BRATTAIN, M.G. (1986). Circumvention of deficient activation in mitomycin C-resistant human colonic carcinoma cells by the mitomycin C analogue BMY 25282. Cancer Res., 46, 3456.
-
(1986)
Cancer Res.
, vol.46
, pp. 3456
-
-
Chakrabarty, S.1
Danels, Y.J.2
Long, B.H.3
Willson, J.K.V.4
Brattain, M.G.5
-
3
-
-
0000338809
-
DT Diaphorase II relation to respiratory chain of intact mitochondria
-
CONOVER, T.E. & ERNSTER, L. (1962). DT Diaphorase II relation to respiratory chain of intact mitochondria. Biochim. Biophys. Acta, 58, 189.
-
(1962)
Biochim. Biophys. Acta
, vol.58
, pp. 189
-
-
Conover, T.E.1
Ernster, L.2
-
4
-
-
0023280679
-
Mitomycin C resistant LI210 leukemia cells: Association with pleiotropic drug resistance
-
DORR, R.T., LIDDIL, J.D., TRENT, J.M. & DALTON, W.S. (1987). Mitomycin C resistant LI210 leukemia cells: association with pleiotropic drug resistance. Biochem. Pharmacol., 36, 3115.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 3115
-
-
Dorr, R.T.1
Liddil, J.D.2
Trent, J.M.3
Dalton, W.S.4
-
5
-
-
50549169947
-
DT Diaphorase I purification from the soluble fraction of rat-liver cytoplasm, and properties
-
ERNSTER, L., DANIELSON, L. & LJUNGGREN, M. (1962). DT Diaphorase I purification from the soluble fraction of rat-liver cytoplasm, and properties. Biochim. Biophyss. Acta, 58, 171.
-
(1962)
Biochim. Biophyss. Acta
, vol.58
, pp. 171
-
-
Ernster, L.1
Danielson, L.2
Ljunggren, M.3
-
6
-
-
0022492516
-
Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells
-
FRACASSO, P.M. & SARTORELLI, A.C. (1986). Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells. Cancer Res., 46, 3939.
-
(1986)
Cancer Res.
, vol.46
, pp. 3939
-
-
Fracasso, P.M.1
Sartorelli, A.C.2
-
7
-
-
0022490341
-
Glutathione levels and cytotoxicity of a thiol activated alkylating agent in human and mouse cells
-
GEARD, C.R. & GEORGSSON, M.A. (1986). Glutathione levels and cytotoxicity of a thiol activated alkylating agent in human and mouse cells. Int. J. Radiat. Oncol. Biol. Phys., 12, 1179.
-
(1986)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.12
, pp. 1179
-
-
Geard, C.R.1
Georgsson, M.A.2
-
8
-
-
0023182182
-
Role of hypoxia in anticancer drug-induced cytotoxicity for Ehrlich Ascites cells
-
GUPTA, V. & CONSTANZI, J.J. (1987). Role of hypoxia in anticancer drug-induced cytotoxicity for Ehrlich Ascites cells. Cancer Res., 47, 2407.
-
(1987)
Cancer Res.
, vol.47
, pp. 2407
-
-
Gupta, V.1
Constanzi, J.J.2
-
9
-
-
0014842505
-
One-electron-transfer reactions in biochemical systems. V: Difference in the mechanism of quinone reduction by the NADH dehydrogenase and the NAD(P)H dehydrogenase (DT-diaphorase)
-
IYANAGI, T. & YAMAZAKI, I. (1970). One-electron-transfer reactions in biochemical systems. V: difference in the mechanism of quinone reduction by the NADH dehydrogenase and the NAD(P)H dehydrogenase (DT-diaphorase). Biochim. Biophys. Acta., 216, 282.
-
(1970)
Biochim. Biophys. Acta.
, vol.216
, pp. 282
-
-
Iyanagi, T.1
Yamazaki, I.2
-
10
-
-
78651117965
-
A molecular mechanism of mitomycin action: Linking of complementary DNA strands
-
IYER, V.N. & SZYBALSKI, W. (1963). A molecular mechanism of mitomycin action: linking of complementary DNA strands. Proc. Natl Acad. Sci. USA, 50, 355.
-
(1963)
Proc. Natl Acad. Sci. USA
, vol.50
, pp. 355
-
-
Iyer, V.N.1
Szybalski, W.2
-
11
-
-
0020578356
-
Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines
-
KARTNER, N., RIORDAN, J R. & LING, V. (1983). Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. Science, 221, 1285.
-
(1983)
Science
, vol.221
, pp. 1285
-
-
Kartner, N.1
Riordan, J.R.2
Ling, V.3
-
12
-
-
0018852436
-
Preferential activation of mitomycin C to cytotoxic metabolites by hypoxic cells
-
KENNEDY, K.A., ROCKWELL, S. & SARTORELLI, A.C. (1980). Preferential activation of mitomycin C to cytotoxic metabolites by hypoxic cells. Cancer Res., 40, 2356.
-
(1980)
Cancer Res.
, vol.40
, pp. 2356
-
-
Kennedy, K.A.1
Rockwell, S.2
Sartorelli, A.C.3
-
13
-
-
0019992640
-
(1982). Metabolic activation of mitomycin C by liver microsomes and nuclei
-
KENNEDY, K.A., SLIGAR, S.G., POLOMSKI, L. & SARTORELLI, A.C. (1982). Metabolic activation of mitomycin C by liver microsomes and nuclei. Biochem. Pharmacol., 31, 2011.
-
(2011)
Biochem. Pharmacol.
, pp. 31
-
-
Kennedy, K.A.1
Sligar, S.G.2
Polomski, L.3
Sartorelli, A.C.4
-
14
-
-
0021687360
-
Role of NADPH: Cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C
-
KEYES, S R., FRACASSO, P.M., HEIMBROOK, D C., ROCKWELL, S., SLIGAR, S.G. & SARTORELLI, A.C. (1984). Role of NADPH: cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C. Cancer Res., 44, 5628.
-
(1984)
Cancer Res.
, vol.44
, pp. 5628
-
-
Keyes, S.R.1
Fracasso, P.M.2
Heimbrook, D.C.3
Rockwell, S.4
Sligar, S.G.5
Sartorelli, A.C.6
-
15
-
-
0021934520
-
Enhancement of mitomycin C cytotoxicity to hypoxic tumor cells by dicoumarol in vivo and in vitro
-
KEYES, S.R., ROCKWELL, S. & SARTORELLI, A.C. (1985a). Enhancement of mitomycin C cytotoxicity to hypoxic tumor cells by dicoumarol in vivo and in vitro. Cancer Res., 45, 213.
-
(1985)
Cancer Res.
, vol.45
, pp. 213
-
-
Keyes, S.R.1
Rockwell, S.2
Sartorelli, A.C.3
-
16
-
-
0021971997
-
Porfiro-mycin as a bioreductive alkylating agent with selective toxicity to hypoxic EMT6 tumor cells in vivo and in vitro
-
KEYES, S.R., ROCKWELL, S. & SARTORELLI, A.C. (1985b). Porfiro-mycin as a bioreductive alkylating agent with selective toxicity to hypoxic EMT6 tumor cells in vivo and in vitro. Cancer Res., 45, 3642.
-
(1985)
Cancer Res.
, vol.45
, pp. 3642
-
-
Keyes, S.R.1
Rockwell, S.2
Sartorelli, A.C.3
-
17
-
-
84918651134
-
Mechanistic studies on dicumarol-enhanced toxicity of mitomycin C and porfiromycin to hypoxic EMT6 tumour cells
-
KEYES, S R., ROCKWELL, S. & SARTORELLI, A.C. (1986). Mechanistic studies on dicumarol-enhanced toxicity of mitomycin C and porfiromycin to hypoxic EMT6 tumour cells. Proc. Am. Assoc. Cancer Res., 27, 233.
-
(1986)
Proc. Am. Assoc. Cancer Res.
, vol.27
, pp. 233
-
-
Keyes, S.R.1
Rockwell, S.2
Sartorelli, A.C.3
-
18
-
-
0023568365
-
Correlation between drug uptake and selective toxicity of porfiromycin to hypoxic EMT6 cells
-
KEYES, S.R., ROCKWELL, S. & SARTORELLI, A.C. (1987). Correlation between drug uptake and selective toxicity of porfiromycin to hypoxic EMT6 cells. Cancer Res., 47, 5654.
-
(1987)
Cancer Res.
, vol.47
, pp. 5654
-
-
Keyes, S.R.1
Rockwell, S.2
Sartorelli, A.C.3
-
19
-
-
0021181835
-
Effects of mitomycin C on human colon carcinoma cells
-
LONG, B.H., WILLSON, J.K.V., BRATTAIN, D.E., MUSIAL, S. & BRATTAIN, M.G. (1984). Effects of mitomycin C on human colon carcinoma cells. J. Natl Cancer Inst., 73, 787.
-
(1984)
J. Natl Cancer Inst.
, vol.73
, pp. 787
-
-
Long, B.H.1
Willson, J.K.V.2
Brattain, D.E.3
Musial, S.4
Brattain, M.G.5
-
20
-
-
0021571170
-
Drug resistance of hypoxic tumour cells
-
LUDWIG, C. (1984). Drug resistance of hypoxic tumour cells in vitro. Cancer Treat. Rev., 11, 173.
-
(1984)
Vitro. Cancer Treat. Rev.
, vol.11
, pp. 173
-
-
Ludwig, C.1
-
21
-
-
0022995459
-
Meaasurement of low levels of oxygen and their effect on respiration in cell suspensions maintained in an open system
-
MARSHALL, R.S., KOCH, C.J. & RAUTH, A.M. (1986). Meaasurement of low levels of oxygen and their effect on respiration in cell suspensions maintained in an open system. Radiat. Res., 108, 91.
-
(1986)
Radiat. Res.
, vol.108
, pp. 91
-
-
Marshall, R.S.1
Koch, C.J.2
Rauth, A.M.3
-
22
-
-
84970062486
-
Aerobic resistance of a human cell strain to mitomycin C and porfiromycin is lost under hypoxic exposure conditions
-
MARSHALL, R.S., PATERSON, M.C. & RAUTH, A.M. (1989). Aerobic resistance of a human cell strain to mitomycin C and porfiromycin is lost under hypoxic exposure conditions. Biochem. Pharmacol., in the press.
-
(1989)
Biochem. Pharmacol.
-
-
Marshall, R.S.1
Paterson, M.C.2
Rauth, A.M.3
-
23
-
-
0022532889
-
Modification of the cytotoxic activity of mitomycin C by oxygen and ascorbic acid in Chinese hamster ovary cells and a repair-deficient mutant
-
MARSHALL, R.S. & RAUTH, A.M. (1986). Modification of the cytotoxic activity of mitomycin C by oxygen and ascorbic acid in Chinese hamster ovary cells and a repair-deficient mutant. Cancer Res., 46, 2709.
-
(1986)
Cancer Res.
, vol.46
, pp. 2709
-
-
Marshall, R.S.1
Rauth, A.M.2
-
24
-
-
0019986881
-
Defective removal of DNA cross-links in a repair-deficient mutant of Chinese hamster ovary cells
-
MEYN, R.E., JENKINS, S.F. & THOMPSON, L.H. (1982). Defective removal of DNA cross-links in a repair-deficient mutant of Chinese hamster ovary cells. Cancer Res., 42, 3106.
-
(1982)
Cancer Res.
, vol.42
, pp. 3106
-
-
Meyn, R.E.1
Jenkins, S.F.2
Thompson, L.H.3
-
25
-
-
0021345793
-
Reductive activation of mitomycin C and mitomycin C metabolites catalyzed by NADPH-cytochrome P450 reductase and xanthine oxidase
-
PAN, S.S., ANDREWS, P.A. & GLOVER, C.J. (1984). Reductive activation of mitomycin C and mitomycin C metabolites catalyzed by NADPH-cytochrome P450 reductase and xanthine oxidase. J. Binl. Client. 259, 959.
-
(1984)
J. Binl. Client.
, vol.259
, pp. 959
-
-
Pan, S.S.1
Rews, P.A.2
Glover, C.J.3
-
26
-
-
8944237964
-
Human cancer-prone disorders, abnormal carcinogen response, and defective DNA metabolism
-
Burns, F.J., Upton, A.C. & Silini, G, Plenum Press: New York
-
PATERSON, M.C., MIDDLESTADT, M.V., WEINFELD, M., MIRZAYANS, R. & GENTNER, N.E. (1986). Human cancer-prone disorders, abnormal carcinogen response, and defective DNA metabolism. In Radiation Carcinogenesis and DNA Alterations, Burns, F.J., Upton, A.C. & Silini, G. (eds) p. 471. Plenum Press: New York.
-
(1986)
Radiation Carcinogenesis and DNA Alterations
, pp. 471
-
-
Paterson, M.C.1
Middlestadt, M.V.2
Weinfeld, M.3
Mirzayans, R.4
Gentner, N.E.5
-
27
-
-
0021625470
-
Binding of the antitumor drug cis-diamminedichloroplatinum(II) (cisplatin) to DNA
-
PINTO, A.L. & LIPPARD, S.J. (1985). Binding of the antitumor drug cis-diamminedichloroplatinum(II) (cisplatin) to DNA. Biochim. Biophys. Acta, 780, 167.
-
(1985)
Biochim. Biophys. Acta
, vol.780
, pp. 167
-
-
Pinto, A.L.1
Lippard, S.J.2
-
28
-
-
0022381212
-
Formation and repair of DNA interstrand crosslinks in relation to cytotoxicity and unscheduled DNA synthesis induced in control and mutant human cells treated with ds-diammine-dichloroplatinum(II)
-
PLOOY, A.C.M., VAN DIJK, M., BERENDS, F. & LOHMAN, P.H.M. (1985). Formation and repair of DNA interstrand crosslinks in relation to cytotoxicity and unscheduled DNA synthesis induced in control and mutant human cells treated with ds-diammine-dichloroplatinum(II). Cancer Res., 45, 4178.
-
(1985)
Cancer Res.
, vol.45
, pp. 4178
-
-
Plooy, A.C.M.1
Van Dijk, M.2
Berends, F.3
Lohman, P.H.M.4
-
29
-
-
0023492702
-
Reaction of nucleic acids with cis-diamminedichloroplatinum(II): Interstrand cross-links
-
RAHMOUNI, A. & LENG, M. (1987). Reaction of nucleic acids with cis-diamminedichloroplatinum(II): interstrand cross-links. Biochemistry, 26, 7229.
-
(1987)
Biochemistry
, vol.26
, pp. 7229
-
-
Rahmouni, A.1
Leng, M.2
-
30
-
-
0021057557
-
Effects of mitomycin C alone and in combination with x-rays on EMT6 mouse mammary tumours
-
ROCKWELL, S. (1983). Effects of mitomycin C alone and in combination with x-rays on EMT6 mouse mammary tumours in vivo. J. Natl Cancer Inst., 71, 765.
-
(1983)
Vivo. J. Natl Cancer Inst.
, vol.71
, pp. 765
-
-
Rockwell, S.1
-
31
-
-
0022474587
-
Effect of some proliferative and environmental factors on the toxicity of mitomycin C to tumour cells
-
ROCKWELL, S. (1986). Effect of some proliferative and environmental factors on the toxicity of mitomycin C to tumour cells in vitro. Int. J. Cancer, 38, 229.
-
(1986)
Vitro. Int. J. Cancer
, vol.38
, pp. 229
-
-
Rockwell, S.1
-
32
-
-
0008401242
-
Mitomycin C and radiation
-
Hill, B. & Bellamy, A. (eds). CRC Press: Boca Raton, FL
-
ROCKWELL, S. & SARTORELLI, A.C. (1989). Mitomycin C and radiation. In Interactions Between Antitumor Drugs and Radiation, Hill, B. & Bellamy, A. (eds). CRC Press: Boca Raton, FL.
-
(1989)
Interactions between Antitumor Drugs and Radiation
-
-
Rockwell, S.1
Sartorelli, A.C.2
-
33
-
-
0022547517
-
Effects of glutathione depletion by buthionine sulfoximine on the sensitivity of EMT6/SF cells to chemotherapy agents or X radiation
-
SHRIEVE, D.C. & HARRIS, J.W. (1986). Effects of glutathione depletion by buthionine sulfoximine on the sensitivity of EMT6/SF cells to chemotherapy agents or X radiation. Int. J. Radiat. Oncol. Biol. Phys., 12, 1171.
-
(1986)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.12
, pp. 1171
-
-
Shrieve, D.C.1
Harris, J.W.2
-
34
-
-
0022410423
-
Occurrence of cytosolic protein and phosphoprotein changes in human colon tumor cells with the development of resistance to mitomycin C
-
TAYLOR, C.W., BRATTAIN, M.G. & YEOMAN, L.C. (1985). Occurrence of cytosolic protein and phosphoprotein changes in human colon tumor cells with the development of resistance to mitomycin C. Cancer Res., 45, 4422.
-
(1985)
Cancer Res.
, vol.45
, pp. 4422
-
-
Taylor, C.W.1
Brattain, M.G.2
Yeoman, L.C.3
-
35
-
-
0018827843
-
A screening method for isolating DNA repair-deficient mutants of CHO cells
-
THOMPSON, L.H., RUBIN, J.S., CLEAVER, J.E., WHITMORE, G.F. & BROOKMAN, K. (1980). A screening method for isolating DNA repair-deficient mutants of CHO cells. Somatic Cell Genet., 6, 391.
-
(1980)
Somatic Cell Genet.
, vol.6
, pp. 391
-
-
Thompson, L.H.1
Rubin, J.S.2
Cleaver, J.E.3
Whitmore, G.F.4
Brookman, K.5
-
36
-
-
0020440918
-
The metabolism of menadione (2-methyl-1, 4-naphthoquinone) by isolated hepatocytes
-
THOR, H., SMITH, M.T., HARTZELL, P., BELLOMO, G., JEWELL, S.A. & ORRENIUS, S. (1982). The metabolism of menadione (2-methyl-1, 4-naphthoquinone) by isolated hepatocytes. J. Biol. Chem., 257, 12419.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 12419
-
-
Thor, H.1
Smith, M.T.2
Hartzell, P.3
Bellomo, G.4
Jewell, S.A.5
Orrenius, S.6
-
37
-
-
0022350639
-
Effects of BMY 25282, a mitomycin C analogue, in mitomycin C-resistant human colon cancer cells
-
WILLSON, J.K., LONG, B.H., CHAKRABARTY, S., BRATTAIN, D.E. & BRATTAIN, M.G. (1985). Effects of BMY 25282, a mitomycin C analogue, in mitomycin C-resistant human colon cancer cells. Cancer Res., 45, 5281.
-
(1985)
Cancer Res.
, vol.45
, pp. 5281
-
-
Willson, J.K.1
Long, B.H.2
Chakrabarty, S.3
Brattain, D.E.4
Brattain, M.G.5
-
38
-
-
0021747481
-
Mitomycin C resistance in a human colon carcinoma cell line associated with cell surface protein alterations
-
WILLSON, J.K.V., LONG, B.H., MARKS, M E., BRATTAIN, D.E., WILEY, J.E. & BRATTAIN, M.G. (1984). Mitomycin C resistance in a human colon carcinoma cell line associated with cell surface protein alterations. Cancer Res., 44, 5880.
-
(1984)
Cancer Res.
, vol.44
, pp. 5880
-
-
Willson, J.K.V.1
Long, B.H.2
Marks, M.E.3
Brattain, D.E.4
Wiley, J.E.5
Brattain, M.G.6
|