Characterization of nicotinic acetylcholine receptor channels of the TE671 human medulloblastoma clonal line

Neuroscience Letters

Volumn 96, Issue 2, 1989, Pages 207-212

  Oswald, Robert E ^a   Papke, Roger L ^a   Lukas, Ronald J ^b  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

Acetylcholine; Medulloblastoma; Nicotinic acetylcholine receptor; Patch clamp; Single channel; TE671

Indexed keywords

ACETYLCHOLINE; ALPHA BUNGAROTOXIN; NICOTINIC RECEPTOR;

CELL CULTURE; HUMAN; HUMAN CELL; INTRACELLULAR RECORDING; ION CHANNEL; MEDULLOBLASTOMA; PATCH CLAMP; PRIORITY JOURNAL;

ACETYLCHOLINE; BUNGAROTOXINS; HUMAN; ION CHANNELS; MEDULLOBLASTOMA; RECEPTORS, NICOTINIC; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR CELLS, CULTURED;

EID: 0024552835     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(89)90059-1     Document Type: Article

References (23)

1. Some properties of acetylcholine receptors in human cultured myotubes
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3. Fast events in single-channel currents activated by acetylcholine and its analogues at frog muscle end-plates
4. Fitting and statistical analysis of single channel records
5. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
6. Single cholinergic receptor channel currents in cultured human muscle
7. The occurrence of long openings in the purified cholinergic receptor channel increase with acetylcholine concentration
8. Kinetic analysis of acetylcholine receptors (AChR) in normal and myasthenic human muscle
9. Functional nicotinic acetylcholine receptors on the clonal line, TE671
10. Relationships between high-affinity binding sites for nicotinic acetylcholine receptor agonists and alpha-bungarotoxin on membranes from rat brain, Torpedo electroplax, and the clonal cell lines, PC12 and TE671
11. Immunochemical and pharmacological distinctions between curaremimetic neurotoxin binding sites of central, autonomic, and peripheral origin
12. Characterization of curaremimetic neurotoxin binding sites on membrane fractions derived from the human medulloblastoma clonal line, TE671
13. Establishment of a human medulloblastoma cell line
14. Evidence for structural dissimilarity in the neurotransmitter binding region of purified acetylcholine receptors from human muscle and Torpedo electric organ
15. Analysis of ligand binding to the synthetic dodecapeptide 185–196 of the acetylcholine receptor alpha subunit
16. Relationships of agonist properties to the single channel kinetics of nicotinic acetylcholine receptors
17. Effects of allosteric ligands on the gating of single channel currents in BC3H-1 cells
18. Neuronal properties of neuroectodermal tumors in vitro
19. The human medulloblastoma cell line TE671 expresses a muscle-like acetylcholine receptor
20. Neuron-like features of TE671 cells: Presence of a functional nicotinic cholinergic receptor
21. A patch clamp study of the partial agonist actions of tubocurarine on rat myotubes