On the regulation of sex-hormone-binding globulin-A challenge of an old dogma and outlines of an alternative mechanism

Journal of Steroid Biochemistry

Volumn 32, Issue 2, 1989, Pages 327-334

  Von Schoultz, Bo ^a   Carlström, Kjell ^b  

^a UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; SEX HORMONE BINDING GLOBULIN; SOMATOMEDIN; THYROID HORMONE;

CONTROLLED STUDY; FEMALE; HUMAN CELL; LIVER; MALE; NORMAL HUMAN; NUTRITION; PUBERTY; REVIEW;

FEMALE; HOMEOSTASIS; HUMAN; LIVER DISEASES; MALE; NUTRITIONAL STATUS; PUBERTY; SEX HORMONE-BINDING GLOBULIN; SEX HORMONES; SUPPORT, NON-U.S. GOV'T; THYROID HORMONES;

EID: 0024538169     PISSN: 00224731     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-4731(89)90272-0     Document Type: Review

References (102)

1. Sex-hormone-binding globulin
2. Sex hormone binding globulin in arterial and in peripheral, hepatic, renal and spermatic venous blood of children and adults
3. Hormonal influences on the secretion of steroid-binding proteins by a human hepatoma-derived cell line
4. Characterization of the plasma sex steroidbinding protein
5. Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma
6. The role of binding proteins in hormone delivery
7. Serum levels of unbound 17β-oestradiol during oral and percutaneous replacement therapy
8. Serum bioavailability of sex steroid hormones
9. The serum transport of steroid hormones
10. Relative binding of testosteroneestradiol binding globulin
11. Sex hormone binding globulin capacity as an index of oestrogenicity or androgenicity in women on oral contraceptive steroids
12. A comparative longitudinal study on sex hormone binding globulin capacity during estrogen replacement therapy
13. Sex hormone binding globulin capacity and postmenopausal hormone replacement therapy
14. Investigation of hirsutism: testosterone is not enough
15. Plasma sex hormone binding globulin and androgen levels in the management of hirsute patients
16. The oestrogenic effects of ethinyloestradiol/polyoestradiol phosphate and estramustine phosphate in patients with prostatic carcinoma
17. Effect of dietary components, including lignans and phytoestrogens, on enterohepatic circulation and liver metabolism of estrogens and on sex hormone binding globulin (SHBG)
18. Efficacy of transdermal estradiol
19. Comparison of plasma protein changes induced by danazol, pregnancy and estrogens
20. A comparison of liver protein induction in postmenopausal women during oral and percutaneous oestrogen replacement therapy
21. Effects of percutaneous estradiol and conjugated estrogens on the level of plasma proteins and triglycerides in postmenopausal women
22. Effects of 10 days administration of percutaneous dihydrotestosterone on the pituitary-testicular axis in normal men
23. Serum sex hormone binding globulin and testosterone binding after estradiol administration, castration and their combination in men with prostatic carcinoma
24. Sex hormone-binding globulin changes with androgen replacement
25. Comparison of hepatic impact of oral and vaginal administration of ethinyl estradiol
26. Effects of oestradiol on sex hormone binding globulin
27. Enhanced hepatic extraction of estrogens used for replacement therapy
28. Steroid-sensitive proteins, growth hormone and somatomedin C in prostatic cancer: effects of parenteral and oral estrogen therapy
29. Oestrogen-related changes in sex hormone binding globulin levels during normal and gonadotrophinstimulated menstrual cycles
30. Serum sex hormone-binding globulin during puberty in girls and in different types of adolescent menstrual cycles
31. Sex hormone-binding globulin changes during the menstrual cycle
32. Oestrogen and thyroxine-binding globulin levels in early normal pregnancy
33. Serum levels of oestrogens and of five “steroid sensitive” proteins in early normal pregnancy
34. Variation with age in the levels of sex-steroid-binding plasma protein as determined by radioimmunoassay
35. 2-glycoprotein and sex hormone binding globulin in patients with prostatic cancer
36. Binding capacity of testosterone-estradiol-binding globulin (TeBG), total and calculated unbound concentrations of testosterone in patients with carcinoma of the prostate treated with orchidectomy or estrogens
37. Progressive decrease in serum sex hormone-binding globulin from infancy to late prepuberty in boys
38. Plasma sex hormone-binding globulin levels decrease during the second decade of life irrespective of pubertal status
39. Relationship of androgenic activity to body fat topography, fat cell morphology and metabolic aberrations in premenopausal women
40. Serum sex hormone binding globulin capacity and the percentage of free estradiol in post menopausal women with and without endometrial carcinoma
41. The effect of weight loss on sex steroid secretion and binding in massively obese women
42. Peripheral hormone levels in healthy subjects during controlled fasting
43. Concentrations of sex hormone binding globulin and corticosteroid binding globulin in serum in relation to cardiovascular risk factors and to 12-year incidence of cardiovascular disease and overall mortality in postmenopausal women
44. Interrelationships between sex hormone-binding globulin and 17β-estradiol, testosterone, 5α-dihydrotestosterone, thyroxine and triiodothyronine in prepubertal and pubertal girls
45. Sex steroids and steroid binding proteins in primary biliary cirrhosis
46. Origin and effects of oestrogens in liver cirrhosis
47. Hormones and liver function
48. Sex teroids and steroid binding proteins in female alcoholic liver disease
49. Specific and non-specific modulation of various liver proteins, especially hormone-binding globulins, by steroids and by antimetabolites
50. Estrogen receptor in the mammalian liver
51. 3H] oestradiol by cytoplasmic protein components of female rat liver
52. Estradiol receptors in human liver
53. Estrogen receptors in hepatocellular carcinoma
54. Estrogen receptor in liver of male and female rats: endocrine regulation and molecular properties
55. Hepatic nuclear estrogen receptor concentrations in the rat—influence of age, sex, gestation, lactation and estrus cycle
56. Sex differences in estrogen binding by cytosolic and nuclear components of rat liver
57. Estrogen receptor in rat liver: translocation to nucleus in vivo
58. Nuclear estrogen receptors in rat liver. Development of assay conditions, characterization and the translocation of oestrogens in vivo
59. Nucleo-cytoplasmic relationship of oestrogen receptors in rat liver during the oestrus cycle and in response to administered natural and synthetic oestrogen
60. Regulation of hepatic drug and steroid metabolism by androgens and estrogens
61. Sex steroid induced changes in hepatic enzymes
62. Multihormonal regulation of the estrogen receptor in rat liver
63. Is growth hormone the pituitary feminizing factor mediating the actions of estradiol on hepatic drug and steroid metabolism?
64. Continuous infusion of growth hormone feminizes hepatic steroid metabolism in the rat
65. Effects of gonadal steroid hormones on the hypothalamo-pituitary-liver axis in the control of sex differences in hepatic steroid metabolism in the rat
66. Growth hormone secretion and action
67. Growth hormone and prolactin: Chemistry, gene organisation, biosynthesis and regulation of gene expression
68. Sexual dimorphism in the control of growth secretion
69. Age- and sex-related differences in episodic growth hormone secretion in the rat
70. Normal and recombinant human growth hormone administered by constant infusion feminize catechol estrogen formation by rat liver microsomes
71. A comparison between the effect of growth hormone on prolactin receptors and estrogen receptors in rat liver
72. Effects of estrogen and growth hormone on steroid sulfatase activity and estrogen binding in rat liver
73. Effects of oestrogen and human growth hormone on pregnancy-associated plasma proteins in the rat
74. Effects of growth hormone on pregnancy associated murine protein-1
75. Secretory pattern of growth hormone regulates plasma levels of pregnancy-associated murine protein-1 in the rat
76. Penis and testicular size in patients with growth hormone insufficiency
77. Anabolic and androgenic effect of testosterone in sexually immature boys and its dependence on growth hormone
78. Acute and chronic estrogen effects upon serum somatomedin activity, growth hormone and prolactin in man
79. Regulation of growth hormone and somatomedin C secretion in postmenopausal women: Effect of physiological estrogen replacement
80. Growth hormone and somatomedin C during postmenopausal replacement with oestrogen alone and in combination with an antioestrogen
81. Effects of hypophysectomy on rat liver donors on net synthesis of specific plasma proteins by the isolated perfused rat liver
82. The influence of age on the 24-hour integrated concentration of growth hormone in normal individuals
83. Effects of sex and age on the 24-hour profile of growth hormone in man; importance of endogenous estradiol concentrations
84. Growth hormone secretion in chronic liver disease
85. The endocrine responses to protein calorie malnutrition
86. Does short-term fasting desensitize human somatotrophs to oral l-dopa stimulation?
87. Growth hormone and the steroid binding β-globulin of human plasma
88. Growth hormone hypersecretory states
89. Synthesis and secretion of insulin-like growth factor and its binding protein by the perfused rat liver: dependence on growth hormone status
90. Insulin-like growth factor I regulates growth hormone secretion and messenger ribonucleic acid levels in human pituitary tumor cells
91. Oestrogens and bone metabolism: a hypothesis
92. Reduction of immunoreactive somatomedin-C during fasting in humans
93. Dietary components that regulate serum somatomedin-C concentrations in humans
94. Effects of fasting on the distribution of cytoplasmic and nuclear oestrogen receptors in rat liver, uterus, pituitary and hypothalamus before and after exogenous oestrogen administration
95. Somatomedin levels in childhood, adolescence and adult life
96. Observations on the role of GH/IGF-1 and sex hormone binding globulin (SHBG) in the pubertal development of growth hormone deficient (GHD) children
97. High serum sex hormone-binding globulin (SHBG) and low serum non-SHBG-bound testosterone in boys with idiopathic hypopituitarism: effect of recombinant human growth hormone treatment
98. Interactions of plasma steroid-binding proteins with cell membranes
99. Interactions between corticosteroid-binding globulin (CBG) and target tissue
100. Sex hormone-binding globulin—still many questions