Localization of the fourth membrane spanning domain as a ligand binding site in the human platelet a2-adrenergic receptor

Biochemistry

Volumn 28, Issue 9, 1989, Pages 4125-4130

  Matsui, Hiroaki ^a   Lefkowitz, Robert J ^a   Caron, Marc G ^a   Regan, John W ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4' AZIDOCLONIDINE; 6 AZIDO 9 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 1H 3 BENZAZEPINE; ALPHA 2 ADRENERGIC RECEPTOR; UNCLASSIFIED DRUG;

BINDING SITE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; THROMBOCYTE MEMBRANE;

AFFINITY LABELS; AMINO ACID SEQUENCE; BLOOD PLATELETS; CELL MEMBRANE; CLONIDINE; HUMAN; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, BETA; SUPPORT, NON-U.S. GOV'T;

EID: 0024537502     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00435a075     Document Type: Article

References (25)

1. Bylund, D. B., & U'Prichard, D. C. (1983) Int. Rev. Neurobiol 24, 343–431.
2. Cerione, R. A., Regan, J. W., Nakata, H., Codina, J., Benovic, J. L., Gierschik, P., Somers, R. L., Spiegel, A. M., Birn-baumer, L., Lefkowitz, R. J., & Caron, M. G. (1986) J. Biol. Chem. 261, 3901–3909.
3. Dixon, R. A. F., Sigal, I. S., Rands, E., Register, R. B., Candelore, M. R., Blake, A. D., & Strader, C. D. (1987) Nature 326, 75–77.
4. Dohlman, H. G., Caron, M. G., & Lefkowitz, R. J. (1987) Biochemistry 26, 2657–2664.
5. Dohlman, H. G., Caron, M. G., Strader, C. D., Amlaiky, N., & Lefkowitz, R. J. (1988) Biochemistry 27, 1813–1817.
6. Jakobs, K. H. (1979) Mol. Cell. Endocrinol. 16, 147–156.
7. Jacobs, E., & Clad, A. (1986) Anal. Biochem. 154, 583–589.
8. Kawahara, R. S., Byington, K. H., & Bylund, D. B. (1985) Eur. J. Pharmacol. 117, 43–50.
9. Kobilka, B. K., Matsui, H., Kobilka, T. S., Yang-Feng, T. L., Francke, U., Caron, M. G., Lefkowitz, R. J., & Regan, J. W. (1987) Science 238, 650–656.
10. Kobilka, B. K., Kobilka, T. S., Daniel, K., Regan, J. W., Caron, M. G., & Lefkowitz, R. J. (1988) Science 240, 1310–1316.
11. Kubo, T., Fukuda, K., Mikami, A., Takahashi, H., Mishina, M., Haga, T., Haga, K., Ichiyama, A., Kangawa, K., Kojima, M., Matsuo, H., Hirose, T., & Numa, S. (1986) Nature 323, 411–416.
12. Lefkowitz, R. J., & Caron, M. G. (1988) J. Biol. Chem. 263, 4993–4996.
13. Masaki, T., Tanabe, M., Nakamura, K., & Soejima, M. (1981) Biochim. Biophys. Acta 660, 44–50.
14. Masu, Y., Nakayama, K., Tamaki, H., Harada, Y., Kuno, M., & Nakanishi, S. (1987) Nature 329, 836–838.
15. Nakata, H., Regan, J. W., & Lefkowitz, R. J. (1986) Biochem. Pharmacol. 35, 4089–4094.
16. Nathans, J., & Hogness, D. S. (1983) Cell 34, 807–814.
17. O'Dowd, B. F., Hnatowich, M., Regan, J. W., Leader, W. M., Caron, M. G., & Lefkowitz, R. J. (1988) J. Biol. Chem. 263, 15985–15992.
18. Peralta, E., Winslow, J., Peterson, G., Smith, D., Ashkenazi, A., Ramachandran, J., Schimerlik, M., & Capon, D. (1987) Science 236, 600–605.
19. Regan, J. W., Nakata, H., DeMarinis, R. M., Caron, M. G., & Lefkowitz, R. J. (1986a) J. Biol. Chem. 261, 3894–3900.
20. Regan, J. W., Raymond, J. R., Lefkowitz, R. J., & DeMarinis, R. M. (1986b) Biochem. Biophys. Res. Commun. 137, 606–613.
21. Repaske, M. G., Nunnari, J. M., & Limbird, L. E. (1987) J. Biol. Chem. 262, 12381–12386.
22. Schenkein, I., Levy, M., Franklin, E. C., & Frangione, B. (1977) Arch. Biochem. Biophys. 182, 64–70.
23. Strader, C. D., Sigal, I. S., Register, R. B., Candelore, M. R., Rands, E., & Dixon, R. A. F. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 4384–4388.
24. Swank, R. T., & Munkres, K. D. (1971) Anal. Biochem. 39, 462–477.
25. Wong, S. K. F., Slaughter, C., Ruoho, A. E., & Ross, E. M. (1988) J. Biol. Chem. 263, 7925–7928.