Inhibition of hydroxyl-radical-generated DNA degradation by metallothionein

Toxicology Letters

Volumn 47, Issue 2, 1989, Pages 191-196

  Abel, Josef ^a   de Ruiter, Nada ^a  

^a Med Inst of Environmental Hygiene   (Germany)

Author keywords

DNA damage; Hydroxyl radicals; Metallothionein

Indexed keywords

GLUTATHIONE; HYDROXYL RADICAL; METALLOTHIONEIN;

ANIMAL CELL; DNA DAMAGE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

CATALASE; DNA; DNA DAMAGE; ELECTROPHORESIS, AGAR GEL; FREE RADICALS; GLUTATHIONE; HYDROXIDES; HYDROXYL RADICAL; METALLOTHIONEIN; SUPEROXIDE DISMUTASE;

EID: 0024523351     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4274(89)90075-1     Document Type: Article

References (14)

1. Oxygen toxicity, oxygen radicals, transition metals and disease
2. Free radical mechanisms in tissue injury
3. Peroxidative reactions in red cell biology
4. Oxygen radicals, hydrogen peroxide, and oxygen toxicity
5. Possible role for metallothionein in protection against radiation-induced oxidative stress: kinetics and mechanism of its reaction with Superoxide and hydroxyl radicals
6. Renal handling of cadmium and cadmium metallothionein: studies on the isolated perfused rat kidney
7. Iron(II) EDTA used to measure helical twist along any DNA molecule
8. DNA footprinting with hydroxyl radical
9. DNA radiation damage and its modification by metallothionein
10. Structure of the metal clusters in rabbit liver metallothionein
11. Determination of Cd-thionein in biological material: comparative standard recovery by five current methods using protein nitrogen for standard calibration
12. Regulation of liver zinc metabolism and metallothionein by cAMP, glucagon and glucocorticoids and suppression of free radicals by zinc
13. Radioresistance in cells with high content of metallothionein
14. Increased metallothionein content in rat liver and kidney following X-irradiation