Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial

British Medical Journal

Volumn 298, Issue 6674, 1989, Pages 636-642

  Pickard, J D ^a   Murray, G D ^a   Illingworth, R ^a   Shaw, M D M ^a   Teasdale, G M ^a   Foy, P M ^a   Humphreys, P R D ^a   Lang, D A ^a   Nelson, R ^a   Richards, P ^a   Sinar, J ^a   Bailey, S ^a   Skene, A ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NIMODIPINE;

BRAIN INFECTION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; HUMAN; MAJOR CLINICAL STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SUBARACHNOID HEMORRHAGE;

EID: 0024515530     PISSN: 02670623     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.298.6674.636     Document Type: Article

References (35)

1. Crompton, M.R. Cerebral infarction following the rupture of cerebral berry aneurysms Brain 1964 10.1093/brain/87.2.263 87 263
2. Symon, L. Disordered cerebrosascular physiology in aneurysmal subarachnoid haemorrhage Acta Neurochir (Wien) 1978 10.1007/BF01809133 41 7
3. Pickard, J.D.; Matheson, M.; Patterson, J.; Wyper, D. Prediction of late ischemic complications after cerebral aneurysm surgery by the intraoperative measurement of cerebral blood flow 7 Neurosurg 1980 10.3171/jns.1980.53.3.0305 53 305
4. Simeone, F.A.; Vinall, P. Mechanisms of contractile response of cerebral artery to externally-applied fresh blood I Neurosurg 1975 43 37
5. Brandt, L.; Andersson, K.E.; Edvinsson, L.; Ljunggren, B. Effects of extracellular calcium and of calcium antagonists on the contractile responses of isolated human pial and mesenteric arteries J Cereb Blood Flow Metabol 1981 10.1038/jcbfm.1981.37 1 339
6. Kazda, S.; Towart, R. Nimodipine: a new calcium antagonistic drug with a preferential cerebrosvascular action Acta Neurochir (Wien) 1982 10.1007/BF01728880 63 259
7. Harper, AM\\,; L, Craigen; S, Kazda Effect of the calcium antagonist, nimodipine, on cerebral blood flow and mctabolism in the primate 1981 1 349 Cereh Blood Flo-w Mletabol
8. Harris, R.J.; NMi, Branston; Svmon, L.; Bayhan, M.; Watson, A. The effects of a calciurn antagonist, nimodipine, upon physiological responses of the cerebral sasculature and its possible influence upon focal cerebral ischemia Stroke 1982 10.1161/01.STR.13.6.759 13 759
9. Haws, C.H.; Heistad, D.D. Effects of nimodipine on cerebral sasoconstrictor responses Am 1984 247 170
10. Grotenhuis, J.A.; Bettag, W.X.I.; Fiebach, B.J.O.; Dabir, K. Intracarotid slow bolus injection of' nimodipine during angiography for treatment of cerebral vasospasm after subarachnoid hemorrhage 1984 61 231
11. Ljunggren, B.; Brandt, L.; Saseland, H. Outcome in 60 consecutive patients treated with early aneurysm operation and intravenous nimodipine 7 Neurosurg 1984 10.3171/jns.1984.61.5.0864 61 864
12. Espinosa, F.; Weir, B.; r, Overton; e al A randomized placebo-controlled double-blind trial of nimodipine after subarachnoid hemorrhage in monkeys. 1. Clinical and radiological findings 1984 61 231
13. Nosko, M.; Weir, B.; Krueger, C. Nimodipine and chronic vasospasm in monkeys I. Clinical and radiological findings. Neurosurgerv 1985 16 129
14. Philippon, J.; Grob, R.; Dagreou, F.; Ni, Guggiari; Rivierez, M.; Viars, P. Prevention of vasospasm in subarachnoid haemorrhage. A controlled study with nimodipine-cta N'eurochir (Wien) 1986 82 110
15. Petruk, K.C.; West, N.I.; Mohr, G. Nimodipine treatment in poor grade aneurysm patients. Results of a multicentre, double-blind, placebo controlled trial 1988 10.3171/jns.1988.68.4.0505 Nreurosurg 68 505
16. Mohsen, F.; Pomonis, S.; Illingworth, R. Prediction of delayed cerebral ischaemia after subarachnoid haemorrhage by computed tomography 1984 10.1136/jnnp.47.11.1197 Neurosurg Psychialry; Neure 47 1197
17. Auer, L.M. Acute operation anid preventive nimodipine improve outcome in patients with ruptured aneurysms Neurosurgerv 1984 10.1227/00006123-198407000-00011 15 57
18. Teasdale, G.M.; Lindsay, K.W.; Allardyce, G.; Dharker, S.; Ward, P. Standardized clinical grading of patients with subarachnoid haemorrhage: a uniform international system? 1985 9 Timing of aneurysm surgery
19. Teasdale, G.N.I. A universal subarachnoid haemorrhage scale: report of a committee of the World Federation of Neurosurgical Societies J Neurol NeurosurgPsychiatry 1988 10.1136/jnnp.51.11.1457 51 1457
20. Jennett, B.; Bond, M. Assessment of outcome after severe brain damage. A practical scale Lancet 1975 10.1016/S0140-6736(75)92830-5 i: 480
21. Gielmers, H.J.; Gorter, K.; de Weerdt Cj; Wiezer, H.J.A. A controlled trial of nimodipine in acute ischemic stroke N EnglJ Med 1988 10.1056/NEJM198801283180402 318 203
22. Neil-Dwver, G.; Mee, E.; Dorrance, D.; Lowe, D. Early intervention with nimodipine in subarachnoid haemorrhage Eur Heart J 1987 K): 41
23. Ohman, J, Heiskanen 0 Effect of nimodipine on the outcome of patients after aneurvsmal subarachnoid hemorrhage and surgery J Neurosurg 1988 10.3171/jns.1988.69.5.0683 69 683
24. Vinge, E.; Andersson, K.E.; Brandt, L.; Ljunggren, B.; Nilsson, L.G.; RosendalHelgesen, S. Pharmacokinetics of nimodipine in patients with aneurysmal subarachnoid haemorrhage Eurj Clin Pharmacol 1986 10.1007/BF00607954 30 421
25. Ramsch, K.D.; AhrG, Tettenborn; D, Auer; L.M. Overview on pharmacokinetics of nimodipine in healthy volunteers and in patients with subarachnoid haemorrhage Neurochirurgia (Stutig) 1985 28 1
26. Stulleken, E.H.; Balestrieri, F.J.; Prough, D.S.; McWhorter, J.M. The hemodvnamic effects of nimodipine in patients anesthetised for cerebral aneurysm clipping Anesthestology 1985 10.1097/00000542-198503000-00023 62 346
27. Merin, R.G. Calcium channel blocking drugs and anesthetics-is the drug interaction beneficial or detrimental? Anesthesiology 1987 10.1097/00000542-198702000-00001 66 111
28. Tettenborn, D.; Dycka, J.; Volberg, E.; Dudden, P. Blood pressure and heart rate during treatment with nimodipine in patients with subarachnoid haemorrhage Neurochirurgia (Stuttg) 1985 28 1
29. O'Neill, P.; West, C.R.; Chadwick, D.W. Post-ictal blood pressure in aneurysmal subarachnoid haemorrhage BrJ Neurosurg 1988 10.3109/02688698808992664 2 153
30. Brandt, L.; Ljunggren, B.; Andersson, K.E. Effects of topical application of a calcium antagonist (nifedipine) on feline cortical pial microvasculature under normal conditions and in focal ischemia J Cereb Blood Flowv Metabol 1983 10.1038/jcbfm.1983.5 3 44
31. Takavasu, M.; Bassett, J.E.; Dacey, R.G. Effects of calcium antagonists on intracerebral penetrating arterioles in rats J Neurosurg 1988 10.3171/jns.1988.69.1.0104 69 104
32. Middlemiss, D.N.; Spedding, M. A functional correlate for the dihydropyridine binding site in rat brain Nature 1985 10.1038/314094a0 314 94
33. Pickard, J.D.; Walker, V.; Vile, J.; Perry, S.; Smythe, P.J.; Hunt, R. Oral nimodipine reduces prostaglandin and thromboxane production by arteries chronically exposed to a periarterial haematoma and the antifibrinolvtic agent tranexamic acid J Neurol Neurosurg Psychiatry 1987 50 1 727-3
34. Phillis, J.W.; O'Regan, M.H.; Walter, G.A. Effects of nifedipine and felodipine on adenosine and inosine release from the hypoxemic rat cerebral cortex J Cereb Blood Flouw Metab 1988 10.1038/jcbfm.1988.47 8 179
35. Pickard JI), Read DH, Lovick AHJ. Preoperative assessment of cercbrosascular reactivity following subarachnoid haemorrhage-clinical correlations Auer, L.M. 1985 47 Ttmtng ofaneurvsm surger