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Volumn 320, Issue 11, 1989, Pages 677-683

A Comparison of Oral Milrinone, Digoxin, and Their Combination in the Treatment of Patients with Chronic Heart Failure

Author keywords

[No Author keywords available]

Indexed keywords

DIGOXIN; MILRINONE;

EID: 0024511994     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198903163201101     Document Type: Article
Times cited : (447)

References (51)
  • 1
    • 0013521665 scopus 로고
    • Heart, failure; evaluation of therapy based on a consideration of natural history
    • In: Braunwald E, Sonnenblick EH, Chakrin LW, Schwartz RP Jr. eds. New York: Raven Press
    • Braunwald E. Heart failure; evaluation of therapy based on a consideration of natural history. In: Braunwald E, Sonnenblick EH, Chakrin LW, Schwartz RP Jr. eds. Milrinone: investigation of new inotropic therapy for congestive heart failure. New York: Raven Press, 1984:1–13.
    • (1984) Milrinone: investigation of new inotropic therapy for congestive heart failure. , pp. 1-13
    • Braunwald, E.1
  • 3
    • 84912808589 scopus 로고
    • Clinical use of cardiac glycosides in congestive heart failure
    • In: Smith TW, ed. Orlando, Fia.: Grune & Stratton
    • Marsh JD, Smith TW. Clinical use of cardiac glycosides in congestive heart failure. In: Smith TW, ed. Digitalis glycosides. Orlando, Fia.: Grune & Stratton, 1986:83–113.
    • (1986) Digitalis glycosides. , pp. 83-113
    • Marsh, J.D.1    Smith, T.W.2
  • 4
    • 8044230119 scopus 로고
    • Digitalis
    • In: Leier CV, ed. New York: Marcel Dekker
    • Lewis RP. Digitalis. In: Leier CV, ed. Cardiotonic drugs: a clinical survey. New York: Marcel Dekker, 1986:85–150.
    • (1986) Cardiotonic drugs: a clinical survey. , pp. 85-150
    • Lewis, R.P.1
  • 5
    • 0021142389 scopus 로고
    • Reevaluation of digitalis efficacy: new light on an old leaf
    • Mulrow CD, Feussner JR, Velez R. Reevaluation of digitalis efficacy: new light on an old leaf. Ann Intern Med 1984; 101: 113–7.
    • (1984) Ann Intern Med , vol.101 , pp. 113-117
    • Mulrow, C.D.1    Feussner, J.R.2    Velez, R.3
  • 6
    • 0022591631 scopus 로고
    • Digitalis — a new controversy regarding an old drug: the pitfalls of inappropriate methods
    • Yusuf S, Wittes J, Bailey K, Furberg C. Digitalis — a new controversy regarding an old drug: the pitfalls of inappropriate methods. Circulation 1986; 73: 14–8.
    • (1986) Circulation , vol.73 , pp. 14-18
    • Yusuf, S.1    Wittes, J.2    Bailey, K.3    Furberg, C.4
  • 7
    • 0020335461 scopus 로고
    • Is digoxin really important in treatment of compensated heart failure? A placebo-controlled crossover study in patients with sinus rhythm
    • Fleg JL, Gottlieb SH, Lakatta EG. Is digoxin really important in treatment of compensated heart failure? A placebo-controlled crossover study in patients with sinus rhythm. Am J Med 1982; 73: 244–50.
    • (1982) Am J Med , vol.73 , pp. 244-250
    • Fleg, J.L.1    Gottlieb, S.H.2    Lakatta, E.G.3
  • 8
    • 85023255894 scopus 로고
    • Epidemiology and general considerations of digitalis toxicity
    • In: Smith TW, ed. Orlando, Fia.: Grune & Stratton
    • Marsh JD, Smith TW. Epidemiology and general considerations of digitalis toxicity. In: Smith TW, ed. Digitalis glycosides. Orlando, Fia.: Grune & Stratton, 1986:217–25.
    • (1986) Digitalis glycosides. , pp. 217-225
    • Marsh, J.D.1    Smith, T.W.2
  • 9
    • 0023829545 scopus 로고
    • Digitalis: mechanisms of action and clinical use
    • Smith TW. Digitalis: mechanisms of action and clinical use. N Engl J Med 1988; 318: 358–65.
    • (1988) N Engl J Med , vol.318 , pp. 358-365
    • Smith, T.W.1
  • 12
    • 0020603329 scopus 로고
    • Characterization of the cardiotonic effects of milrinone, a new and potent cardiac bipyridine, on isolated tissues from several animal species
    • Alousi AA, Stankus GP, Stuart JC, Walton LH. Characterization of the cardiotonic effects of milrinone, a new and potent cardiac bipyridine, on isolated tissues from several animal species. J Cardiovasc Pharmacol 1983; 5: 804–11.
    • (1983) J Cardiovasc Pharmacol , vol.5 , pp. 804-811
    • Alousi, A.A.1    Stankus, G.P.2    Stuart, J.C.3    Walton, L.H.4
  • 13
    • 0020570966 scopus 로고
    • Cardiotonic activity of milrinone, a new and potent cardiac bipyridine, on the normal and failing heart of experimental animals
    • Alousi AA, Canter JM, Montenaro MJ, Fort DJ, Ferrari RA. Cardiotonic activity of milrinone, a new and potent cardiac bipyridine, on the normal and failing heart of experimental animals. J Cardiovasc Pharmacol 1983; 5: 792–803.
    • (1983) J Cardiovasc Pharmacol , vol.5 , pp. 792-803
    • Alousi, A.A.1    Canter, J.M.2    Montenaro, M.J.3    Fort, D.J.4    Ferrari, R.A.5
  • 14
    • 0022001187 scopus 로고
    • Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure
    • Jaski BE, Fifer MA, Wright RF, Braunwald E, Colucci WS. Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. J Clin Invest 1985; 75: 643–9.
    • (1985) J Clin Invest , vol.75 , pp. 643-649
    • Jaski, B.E.1    Fifer, M.A.2    Wright, R.F.3    Braunwald, E.4    Colucci, W.S.5
  • 15
    • 0021867398 scopus 로고
    • Physiologic assessment of the inotropic, vasodilator and afterload reducing effects of milrinone in subjects without cardiac disease
    • Borow KM, Come PC, Neumann A, Baim DS, Braunwald E, Grossman W. Physiologic assessment of the inotropic, vasodilator and afterload reducing effects of milrinone in subjects without cardiac disease. Am J Cardiol 1985; 55: 1204–9.
    • (1985) Am J Cardiol , vol.55 , pp. 1204-1209
    • Borow, K.M.1    Come, P.C.2    Neumann, A.3    Baim, D.S.4    Braunwald, E.5    Grossman, W.6
  • 16
    • 0022592684 scopus 로고
    • Separation of the direct myocardial and vasodilator actions of milrinone administered by an intracoronary infusion technique
    • Ludmer PL, Wright RF, Arnold JM, Ganz P, Braunwald E, Colucci WS. Separation of the direct myocardial and vasodilator actions of milrinone administered by an intracoronary infusion technique. Circulation 1986; 73: 130–7.
    • (1986) Circulation , vol.73 , pp. 130-137
    • Ludmer, P.L.1    Wright, R.F.2    Arnold, J.M.3    Ganz, P.4    Braunwald, E.5    Colucci, W.S.6
  • 17
    • 0021819985 scopus 로고
    • Milrinone in heart failure: acute effects on left ventricular systolic function and myocardial metabolism
    • Timmis AD, Smyth P, Monaghan M, et al. Milrinone in heart failure: acute effects on left ventricular systolic function and myocardial metabolism. Br Heart J 1985; 54: 36–41.
    • (1985) Br Heart J , vol.54 , pp. 36-41
    • Timmis, A.D.1    Smyth, P.2    Monaghan, M.3
  • 18
    • 0021711224 scopus 로고
    • Improvement in indexes of diastolic performance in patients with congestive heart failure treated with milrinone
    • Monrad ES, McKay RG, Baim DS, et al. Improvement in indexes of diastolic performance in patients with congestive heart failure treated with milrinone. Circulation 1984; 70: 1030–7.
    • (1984) Circulation , vol.70 , pp. 1030-1037
    • Monrad, E.S.1    McKay, R.G.2    Baim, D.S.3
  • 19
    • 0022592049 scopus 로고
    • Identification of the direct vasodilator effect of milrinone with an isolated limb preparation in patients with chronic congestive heart failure
    • Cody RJ, Muller FB, Kubo SH, Rutman H, Leonard D. Identification of the direct vasodilator effect of milrinone with an isolated limb preparation in patients with chronic congestive heart failure. Circulation 1986; 73: 124–9.
    • (1986) Circulation , vol.73 , pp. 124-129
    • Cody, R.J.1    Muller, F.B.2    Kubo, S.H.3    Rutman, H.4    Leonard, D.5
  • 20
    • 0022528880 scopus 로고
    • Biochemical mechanisms for the inotropic effect of the cardiotonic drug milrinone
    • Earl CQ, Linden J, Weglicki WB. Biochemical mechanisms for the inotropic effect of the cardiotonic drug milrinone. J Cardiovasc Pharmacol 1986; 8: 864–72.
    • (1986) J Cardiovasc Pharmacol , vol.8 , pp. 864-872
    • Earl, C.Q.1    Linden, J.2    Weglicki, W.B.3
  • 21
    • 0023102890 scopus 로고
    • Mechanism of the positive inotropic effect of milrinone in cultured embryonic chick ventricular cells
    • Olson EM, Kim D, Smith TW, Marsh JD. Mechanism of the positive inotropic effect of milrinone in cultured embryonic chick ventricular cells. J Mol Cell Cardiol 1987; 19: 95–104.
    • (1987) J Mol Cell Cardiol , vol.19 , pp. 95-104
    • Olson, E.M.1    Kim, D.2    Smith, T.W.3    Marsh, J.D.4
  • 22
    • 0022342871 scopus 로고
    • Milrinone and thyroid hormone stimulate myocardial membrane Ca2+-ATPase activity and share structural homologies
    • Mylotte KM, Cody V, Davis PJ, Davis FB, Bias SD, Schoenl M. Milrinone and thyroid hormone stimulate myocardial membrane Ca2+-ATPase activity and share structural homologies. Proc Natl Acad Sci USA 1985; 82: 7974–8.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7974-7978
    • Mylotte, K.M.1    Cody, V.2    Davis, P.J.3    Davis, F.B.4    Bias, S.D.5    Schoenl, M.6
  • 23
    • 0020605971 scopus 로고
    • Evaluation of a new bipyridine inotropic agent — milrinone — in patients with severe congestive heart failure
    • Baim DS, McDowell AV, Cherniles J, et al. Evaluation of a new bipyridine inotropic agent — milrinone — in patients with severe congestive heart failure. N Engl J Med 1983; 309: 748–56.
    • (1983) N Engl J Med , vol.309 , pp. 748-756
    • Baim, D.S.1    McDowell, A.V.2    Cherniles, J.3
  • 24
    • 0020567448 scopus 로고
    • Sustained hemodynamic and clinical effects of a new cardiotonic agent, WIN 47203. in patients with severe congestive heart failure
    • Maskin CS, Sinoway L, Chadwick B, Sonnenblick EH, LeJemtel TH. Sustained hemodynamic and clinical effects of a new cardiotonic agent, WIN 47203. in patients with severe congestive heart failure. Circulation 1983; 67: 1065–70.
    • (1983) Circulation , vol.67 , pp. 1065-1070
    • Maskin, C.S.1    Sinoway, L.2    Chadwick, B.3    Sonnenblick, E.H.4    LeJemtel, T.H.5
  • 25
    • 0020533858 scopus 로고
    • Long-term therapy with a new cardiotonic agent, WIN 47203; drug-dependent improvement in cardiac performance and progression of the underlying disease
    • Sinoway LS, Maskin CS, Chadwick B, Forman R, Sonnenblick EH, LeJemtel TH. Long-term therapy with a new cardiotonic agent, WIN 47203; drug-dependent improvement in cardiac performance and progression of the underlying disease. J Am Coll Cardiol 1983; 2: 327–31.
    • (1983) J Am Coll Cardiol , vol.2 , pp. 327-331
    • Sinoway, L.S.1    Maskin, C.S.2    Chadwick, B.3    Forman, R.4    Sonnenblick, E.H.5    LeJemtel, T.H.6
  • 26
    • 0021876839 scopus 로고
    • Milrinone in congestive heart failure: acute and chronic hemodynamic and clinical evaluation
    • Simonton CA, Chatterjee K, Cody RJ, et al. Milrinone in congestive heart failure: acute and chronic hemodynamic and clinical evaluation. J Am Coll Cardiol 1985; 6: 453–9.
    • (1985) J Am Coll Cardiol , vol.6 , pp. 453-459
    • Simonton, C.A.1    Chatterjee, K.2    Cody, R.J.3
  • 27
    • 0021877050 scopus 로고
    • Milrinone in heart failure: effects on exercise haemodynamics during short term treatment
    • Timmis AD, Smyth P, Jewett DE. Milrinone in heart failure: effects on exercise haemodynamics during short term treatment. Br Heart J 1985: 54: 42–7.
    • (1985) Br Heart J , vol.54 , pp. 42-47
    • Timmis, A.D.1    Smyth, P.2    Jewett, D.E.3
  • 28
    • 0021846577 scopus 로고
    • Immediate effects of milrinone on metabolic and sympathetic responses to exercise in severe congestive heart failure
    • White HD, Ribeiro JP, Hartley LH, Colucci WS. Immediate effects of milrinone on metabolic and sympathetic responses to exercise in severe congestive heart failure. Am J Cardiol 1985; 56: 93–8.
    • (1985) Am J Cardiol , vol.56 , pp. 93-98
    • White, H.D.1    Ribeiro, J.P.2    Hartley, L.H.3    Colucci, W.S.4
  • 29
    • 0021847329 scopus 로고
    • Systemic and regional hemodynamic effects of captopril and milrinone administered alone and concomitantly in patients with heart failure
    • LeJemtel TH, Maskin CS, Mancini D, Sinoway L, Feld H, Chadwick B. Systemic and regional hemodynamic effects of captopril and milrinone administered alone and concomitantly in patients with heart failure. Circulation 1985; 72: 364–9.
    • (1985) Circulation , vol.72 , pp. 364-369
    • LeJemtel, T.H.1    Maskin, C.S.2    Mancini, D.3    Sinoway, L.4    Feld, H.5    Chadwick, B.6
  • 31
    • 0015425884 scopus 로고
    • Treadmill exercise in assessment of functional capacity of patients with cardiac disease
    • Patterson JA, Naughton J, Pietras RJ, Gunnar RN. Treadmill exercise in assessment of functional capacity of patients with cardiac disease. Am J Cardiol 1972; 30: 757–62.
    • (1972) Am J Cardiol , vol.30 , pp. 757-762
    • Patterson, J.A.1    Naughton, J.2    Pietras, R.J.3    Gunnar, R.N.4
  • 32
    • 0020410785 scopus 로고
    • Psychophysical bases of perceived exertion
    • Borg GAV. Psychophysical bases of perceived exertion. Med Sci Sports Exerc 1982; 14: 377–81.
    • (1982) Med Sci Sports Exerc , vol.14 , pp. 377-381
    • Borg, G.A.V.1
  • 33
    • 0021345989 scopus 로고
    • Flecainide: its proarrhythmic effect and expected changes on the surface electrocardiogram
    • Morganroth J, Horowitz LN. Flecainide: its proarrhythmic effect and expected changes on the surface electrocardiogram. Am J Cardiol 1984; 53: 89B–94B.
    • (1984) Am J Cardiol , vol.53 , pp. 89B-94B
    • Morganroth, J.1    Horowitz, L.N.2
  • 34
    • 0022549338 scopus 로고
    • Classification by type of ventricular proarrhythmia predicts frequency of adverse cardiac events from flecainide
    • Morganroth J, Anderson JL, Gentzkow GD. Classification by type of ventricular proarrhythmia predicts frequency of adverse cardiac events from flecainide. J Am Coll Cardiol 1986; 8: 607–15.
    • (1986) J Am Coll Cardiol , vol.8 , pp. 607-615
    • Morganroth, J.1    Anderson, J.L.2    Gentzkow, G.D.3
  • 35
    • 0023191537 scopus 로고
    • Application of a frequency definition of ventricular proarrhythmia
    • Morganroth J, Borland M, Chao G. Application of a frequency definition of ventricular proarrhythmia. Am J Cardiol 1987; 59: 97–9.
    • (1987) Am J Cardiol , vol.59 , pp. 97-99
    • Morganroth, J.1    Borland, M.2    Chao, G.3
  • 36
    • 0021723922 scopus 로고
    • Oral amrinone for the treatment of chronic congestive heart failure: results of a multicenter randomized double-blind and placebo-controlled withdrawal study
    • DiBianco R, Shabetai R, Silverman BD, Leier CV, Benotti JR. Oral amrinone for the treatment of chronic congestive heart failure: results of a multicenter randomized double-blind and placebo-controlled withdrawal study. J Am Coll Cardiol 1984; 4: 855–66.
    • (1984) J Am Coll Cardiol , vol.4 , pp. 855-866
    • DiBianco, R.1    Shabetai, R.2    Silverman, B.D.3    Leier, C.V.4    Benotti, J.R.5
  • 37
    • 0021865534 scopus 로고
    • Long-term oral administration of amrinone for congestive heart failure: lack of efficacy in a multicenter controlled trial
    • Massie B, Bourassa M, DiBianco R, et al. Long-term oral administration of amrinone for congestive heart failure: lack of efficacy in a multicenter controlled trial. Circulation 1985; 71: 963–71.
    • (1985) Circulation , vol.71 , pp. 963-971
    • Massie, B.1    Bourassa, M.2    DiBianco, R.3
  • 39
    • 0019328372 scopus 로고
    • Long-term digitalis therapy improves left ventricular function in heart failure
    • Arnold SB, Byrd RC, Meister W, et al. Long-term digitalis therapy improves left ventricular function in heart failure. N Engl J Med 1980; 303: 1443–8.
    • (1980) N Engl J Med , vol.303 , pp. 1443-1448
    • Arnold, S.B.1    Byrd, R.C.2    Meister, W.3
  • 40
    • 0020042810 scopus 로고
    • Heart failure in outpatients: a randomized trial of digoxin versus placebo
    • Lee DC-S, Johnson RA, Bingham JB, et al. Heart failure in outpatients: a randomized trial of digoxin versus placebo. N Engl J Med 1982; 306: 699–705.
    • (1982) N Engl J Med , vol.306 , pp. 699-705
    • Lee, D.C.-S.1    Johnson, R.A.2    Bingham, J.B.3
  • 41
    • 0017344651 scopus 로고
    • Maintenance digoxin after an episode of heart failure: placebo-controlled trial in outpatients
    • Dobbs SM, Kenyon WI, Dobbs RJ. Maintenance digoxin after an episode of heart failure: placebo-controlled trial in outpatients. Br Med J 1977; 1: 749–52.
    • (1977) Br Med J , vol.1 , pp. 749-752
    • Dobbs, S.M.1    Kenyon, W.I.2    Dobbs, R.J.3
  • 42
    • 0024294162 scopus 로고
    • Comparative effects of therapy with captopril and digoxin in patients with mild to moderate heart failure
    • Captopril-Digoxin Multicenter Research Group. Comparative effects of therapy with captopril and digoxin in patients with mild to moderate heart failure. JAMA 1988; 259: 539–44.
    • (1988) JAMA , vol.259 , pp. 539-544
  • 43
    • 0020569706 scopus 로고
    • Effects of discontinuing maintenance digoxin therapy in patients with ischemic heart disease and congestive heart failure in sinus rhythm
    • Gheorghiade M, Beller GA. Effects of discontinuing maintenance digoxin therapy in patients with ischemic heart disease and congestive heart failure in sinus rhythm. Am J Cardiol 1983; 51: 1243–50.
    • (1983) Am J Cardiol , vol.51 , pp. 1243-1250
    • Gheorghiade, M.1    Beller, G.A.2
  • 44
    • 0018221397 scopus 로고
    • The clinical value of digoxin in patients with heart failure and sinus rhythm
    • McHaffie D, Purcell H, Mitchell-Heggs P, Guz A. The clinical value of digoxin in patients with heart failure and sinus rhythm. Q J Med 1978; 47: 401–19.
    • (1978) Q J Med , vol.47 , pp. 401-419
    • McHaffie, D.1    Purcell, H.2    Mitchell-Heggs, P.3    Guz, A.4
  • 45
    • 85023222455 scopus 로고
    • The effect of ouabain pretreatment on relaxation induced by milrinone and other vasodilators in guinea pig aortic preparations
    • Report no. 86–67. Rensselaer, N.Y.: Sterling-Winthrop Research Institute
    • Harris A, Lemp B, Silver P. The effect of ouabain pretreatment on relaxation induced by milrinone and other vasodilators in guinea pig aortic preparations. Report no. 86–67. Rensselaer, N.Y.: Sterling-Winthrop Research Institute, 1987.
    • (1987)
    • Harris, A.1    Lemp, B.2    Silver, P.3
  • 46
    • 0022412572 scopus 로고
    • Acute effects of digoxin on total systemic vascular resistance in congestive heart failure due to dilated cardiomyopathy: a hemodynamic-hormonal study
    • Ribner HS, Plucinski DA, Hsieh AM, et al. Acute effects of digoxin on total systemic vascular resistance in congestive heart failure due to dilated cardiomyopathy: a hemodynamic-hormonal study. Am J Cardiol 1985; 56: 896–904.
    • (1985) Am J Cardiol , vol.56 , pp. 896-904
    • Ribner, H.S.1    Plucinski, D.A.2    Hsieh, A.M.3
  • 47
    • 0022384823 scopus 로고
    • Sudden unexpected death in patients with congestive heart failure: a second frontier
    • Packer M. Sudden unexpected death in patients with congestive heart failure: a second frontier. Circulation 1985; 72: 681–5.
    • (1985) Circulation , vol.72 , pp. 681-685
    • Packer, M.1
  • 48
    • 0023244711 scopus 로고
    • Effect of milrinone on complex ventricular arrhythmias in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    • Ludmer PL, Baim DS, Antman EM, et al. Effect of milrinone on complex ventricular arrhythmias in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 1987; 59: 1351–5.
    • (1987) Am J Cardiol , vol.59 , pp. 1351-1355
    • Ludmer, P.L.1    Baim, D.S.2    Antman, E.M.3
  • 50
    • 0022590640 scopus 로고
    • Occurrence of ventricular arrhythmias in patients receiving acute and chronic infusions of milrinone
    • Anderson JL, Askins JC, Gilbert EM, Menlove RL, Lutz JR. Occurrence of ventricular arrhythmias in patients receiving acute and chronic infusions of milrinone. Am Heart J 1986; 111: 466–74.
    • (1986) Am Heart J , vol.111 , pp. 466-474
    • Anderson, J.L.1    Askins, J.C.2    Gilbert, E.M.3    Menlove, R.L.4    Lutz, J.R.5
  • 51
    • 0022253264 scopus 로고
    • Milrinone in congestive heart failure: observations on ambulatory ventricular arrhythmias
    • Holmes JR, Kubo SH, Cody RJ, Kligfield P. Milrinone in congestive heart failure: observations on ambulatory ventricular arrhythmias. Am Heart J 1985; 110: 800–6.
    • (1985) Am Heart J , vol.110 , pp. 800-806
    • Holmes, J.R.1    Kubo, S.H.2    Cody, R.J.3    Kligfield, P.4


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