Isoferritins in HIV infection: Relation to clinical stage, CD8 lymphocyte binding and the pathogenesis of aids

AIDS

Volumn 3, Issue 1, 1989, Pages 11-16

  Moroz, Chaya ^a   Misrock, S Leslie ^b   Siegalt, Frederick P ^c  

^a TEL AVIV UNIVERSITY   (Israel)

^b Pennie and Edmonds   (United States)

^c LONG ISLAND JEWISH MEDICAL CENTER   (United States)

Author keywords

AIDS related complex; Ferritins; Immunodeficiency; Immunology; Immunosuppression; Isoferritins; Lymphocytes; Oncofetal; Pathogenesis; Placental

Indexed keywords

CD4 ANTIGEN; FERRITIN; ISOFERRITIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AIDS RELATED COMPLEX; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; LYMPHADENOPATHY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; T LYMPHOCYTE;

ACQUIRED IMMUNODEFICIENCY SYNDROME; AIDS-RELATED COMPLEX; ANTIBODIES, MONOCLONAL; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FERRITIN; HUMAN; IMMUNE TOLERANCE; LEVAMISOLE; LYMPHOCYTES; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0024507499     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Hancock BW, Bruce L, May K, Richmond J: Ferritin, a sensitizing substance in the leucocyte migration inhibition test in patients with malignant lymphoma. Br J Haematol 1979, 43:223-227.
2. Moroz C, Kupfer B: Suppressor-cell activity of ferritin-bearing lymphocytes in patients with breast cancer. Isr J Med Sci 1981, 17:879-881.
3. Hann H-WL, Stahlhut MW, Chung LC: Ferritinemia in cancer. Nature 1984, 265:755-756.
4. Matzner Y, Konijn AM, Shlomai Z, Ben-Basat H: Differential effect of isolated placental isoferritins on in vitro T-lymphocyte function. Br J Haematol 1985, 59:443-448.
5. Broxmeyer HE, Gentile P, Cooper S. et al.: Functional activities of acidic isoferritins and lactoferrin in vitro and in vivo Blood Cells 1984, 10:397-400
6. Moroz C, Lahat N, Biniaminov M, Ramot B: Ferritin on the surface of lymphocytes in Hodgkin's disease patients. A possible blocking substance removed by levamisole. Clin Exp Immunol 1977, 29:30-35.
7. Moroz C, Giler SH, Kupfer B, Urea I: Lymphocytes bearing surface ferritin in patients with Hodgkin's disease and breast cancer. N Engl J Med 1977, 296:1175.
8. Moroz C, Giler SH, Kupfer B, Urea I: Ferritin bearing lymphocytes and T cell levels in peripheral blood of patients with breast cancer. Cancer Immunol Immunother 1977, 3:101-104.
9. Moroz C, Kan M, Chaimof C, et al.: Ferritin-bearing lymphocytes in the diagnosis of breast cancer. Cancer 1984, 54:84-89.
10. Levo Y, Ramot B, Rotter V: Restoration of cellular immune response by levamisole in patients with Hodgkin's disease. Biomedicine 1975, 23:198-200.
11. Ramot B, Biniaminov M, Shoham Ch, Rosenthal E: The effect of levamisole on E-rosette forming cells in vivo and in vitro in Hodgkin's disease patients N Engl J Med 1976, 294:809.
12. Moroz C, Kupfer B, Twig SH, Parhami-Seren B: Preparation and characterization of monoclonal antibodies specific to placenta ferritin. Clin Chim Acta 1985, 148:111-118.
13. Moroz C, Bessler H, Sirota L, et al.: Difference in the placental ferritin levels measured by a specific monoclonal antibody enzymoassay in preterm and term delivery. Clin Exp Immunol 1987, in press.
14. Moroz C, Bessler H, Lurie Y, Shaklai M: A new monoclonal antibody enzymoassay for the specific measurement of placental ferritin isotype in hematologic malignancies. Exp Hematol 1987, 22. 15:258-262.
15. Siegal FP, Lopez C, Fitzgerald PA, et al.: Opportunistic infections in acquired immune deficiency syndrome result from synergistic defects of both the natural and adaptive components of cellular immunity. J Clin Invest 1986, 78:115-123.
16. Centers for Disease Control: Update on acquired immune deficiency syndrome (AIDS)-United States. MMWR 1982, 31:507-514.
17. Engvall E, Perlman P: Enzyme-linked immunosorbent assay (ELISA). Quantitation of specific antibodies by enzyme-labelled anti-immunoglobulin in antigen coated tubes. J Immunol 1972, 109:129-132
18. Voller A, Diaper CC. Bidwell DE, Bartelet A: Microplate enzyme-linked immunosorbent assay for Chagas disease. Lancet 1975, 1:426.
19. Blumberg B, Hahn HWL, Mildvan D, et al.: Iron and iron binding proteins in persistent generalised lymphadenopathy and AIDS. Lancet 1984, 1:347.
20. Gupta S, Imam A, Likorish K: Serum ferritin in acquired immune deficiency syndrome (AIDS), AIDS-related complex and healthy heterosexual men. J Clin Lab Immunol 1986, 20:11-13.
21. Nekam K, Fudenberg HH, Mandi B, Lang I, Gergely P, Petranyl G: Synthesis of trypsinized sheep red blood cell receptors on human lymphocytes, comparison of the effects of immunopotentia-tors of biological and synthetic origin in vitro. Immunopharmacol-ogy 1981, 3:31-10.
22. Walker CM, Moody IJ, Steiles DP, Levy JA: CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication. Science 1986, 234:1563-1566.