Reversible middle cerebral artery occlusion without craniectomy in rats

Stroke

Volumn 20, Issue 1, 1989, Pages 84-91

  Longa, Enrique Zea ^a,b,c   Weinstein, Philip R ^a,b,c   Carlson, Sara ^a,b,c   Cummins, Robert ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

Author keywords

Animal models; Cerebral arteries; Cerebral ischemia; Rats

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN ISCHEMIA; HISTOLOGY; MALE; MAMMAL; MIDDLE CEREBRAL ARTERY; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; RAT;

ANIMAL; ARTERIAL OCCLUSIVE DISEASES; BRAIN; CEREBRAL ARTERIES; CRANIOTOMY; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; MALE; NERVOUS SYSTEM; RATS; RATS, INBRED STRAINS; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUTURE TECHNIQUES; TIME FACTORS;

EID: 0024494427     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/01.STR.20.1.84     Document Type: Article

References (22)

1. Brown AW, Brierley JB: Anoxic ischemic cell changes in rat brain: Light microscopic and fine structural observations. J Neurol Sci 1972; 16: 59-84
2. Dienel GA, Pulsinelli WA, Duffy TE: Regional protein synthesis in rat brain following acute hemispheric ischemia. J Neurochem 1980; 35: 1216-1226
3. Eklof B, Siesjo B: The effect of bilateral carotid ligation upon the blood flow and energy state of rat brain. Acta Physiol Scand 1972; 86: 155-165
4. Furlow TW, Martin RM, Harrison LE: Simultaneous measurement of local glucose utilization and blood flow in the rat brain: An auto radiographic method using two tracers labeled with carbon-14. J Cereb Blood Flow Metab 1983; 3: 62-66
5. Laas R, Igloffstein J, Meyerhoff S: Cerebral infarction due to carotid occlusion and carbon monoxide exposure. J Neurol Neurosurg Psychiatry 1983; 4: 756-773
6. Levine S: Anoxic-ischemic encephalopathy in rats. Am J Pathol 1960; 36: 1-17
7. Lear LJ, Ackermann R, Kameyama M: Multiple-radionuclide autoradiography in evaluation of cerebral function. J Cereb Blood Flow Metab 1984; 4: 264-269
8. Salford LG, Plum F, Brierley JB: Graded hypoxia-oligemia in rat brain. Arch Neurot 1973; 29: 227-238
9. Yanagihara T: Experimental stroke in gerbils: Correlation of clinical pathological and electroencephalographic findings and protein synthesis. Stroke 1978; 9: 155-159
10. Yoshimine T, Yanagihara T: Regional cerebral ischemia by occlusion of the posterior communicating artery and the middle cerebral artery in gerbils. J Neurosurg 1983; 58: 362-367
11. Coyle P: Middle cerebral artery occlusion in the young rat. Stroke 1982; 13: 855-859
12. Tamura A, Graham ID, McCulloch J, Teasdale MG: Focal cerebral ischaemia in the rat. J Cereb Blood Flow Metab 1981; 1: 53-69
13. Tyson WG, Teasdale MG, Graham ID, McCulloch J: Cerebrovascular permeability following MCA occlusion in the rat. J Neurosurg 1982; 57: 186-196
14. Bannister CM, Chapman SA: Ischemia and revascularizalion of the middle cerebral territory of the rat brain by manipulation of the btood vessels in the neck. Surg Neurol 1984; 21: 351-357
15. Koizumi J, Nakazawa T, Yoshida Y: Reperfusable brain infarction model in the rat (abstract). Proceedings of the 10th Meeting of the Japanese Stroke Society, Kyoto, Japan, April 18-19, 1985, p 159
16. Pulsinelli WA, Brierley JB: A new model of bilateral hemispheric ischemia in the anesthetized rat. Stroke 1979; 10: 267-272
17. Fallon JT: Simplified method for histochemical demonstration of experimental myocardial infarct. Circulation 1979; 60 (suppl 2): 11-42
18. Lie JT, Parolero PC, Holley KE, Titus JL: Macroscopic enzyme-mapping verification of large, homogeneous experimental myocardial infarctions of predictable size and location in dogs. J Thorac Cardiovasc Surg 1975; 69: 599-605
19. Bederson JB, Pitts LH, Nishimura MC, Davis RL, Bartkowski HM: Evaluation of 2, 3, 5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 1986; 17: 1304-1308
20. Coyle P: Arterial patterns of the rat rhinencephalon and related structures. Exp Neurol 1975; 49: 671-690
21. Rieke KG, Bowers ED, Penn P: Vascular supply pattern to rat caudoputamen and globus pallidus: Scanning electronmicroscopic study of vascular endocast of stroke-prone vessels. Stroke 1981; 12: 840-846
22. Adams PM, Damasio CM, Putman FS, Damasio RA: Middle cerebral artery occlusion as a cause of isolated subcortical infarction. Stroke 1983; 14: 948-952