Characterization of two immunoglobulin VH genes that are homologous to human rheumatoid factors

Arthritis & Rheumatism

Volumn 32, Issue 1, 1989, Pages 72-76

  Chen, Pojen P ^a   Liu, Ming‐Fei ^a   Glass, Charles A ^a   Sinha, Suman ^a   Kipps, Thomas J ^a   Carson, Dennis A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULINS, HEAVY CHAIN; RHEUMATOID FACTOR; IMMUNOGLOBULIN;

AMINO ACID SEQUENCE; ARTICLE; DNA BASE COMPOSITION; GENETICS; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; ABSTRACT REPORT; ETIOLOGY; GERM LINE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BASE COMPOSITION; BASE SEQUENCE; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOGLOBULINS, HEAVY-CHAIN; MOLECULAR SEQUENCE DATA; RHEUMATOID FACTOR; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0024476916     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/anr.1780320112     Document Type: Article

References (15)

1. Cross‐reacting idiotypes on cryoprecipitating rheumatoid factor
2. Complete amino acid sequence of variable domains from two monoclonal human antigamma globulins of the Wa cross‐idiotypic group: suggestion that the J segments are involved in the structural correlate of the idiotype
3. Complete amino acid sequences of variable regions of two human IgM rheumatoid factors, BOR and KAS of the Wa idiotypic family, reveal restricted use of heavy and light chain variable and joining region gene segments
4. Early restriction of the human antibody repertoire
5. Organization and evolution of variable region genes of the human immunoglobulin heavy chain
6. Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus
7. Evolutionary aspects of immunoglobulin heavy chain variable region (V(H)) gene subgroups
8. Rearranged immunoglobulin heavy chain variable region (Vh) pseudogene that deletes the second complementarity‐determining region
9. Human retinoblastoma susceptibility gene: cloning, identification, and sequence
10. Structure of the human immunoglobulin μ locus: characterization of embryonic and rearranged J and D genes
11. The genetic origin of human autoantibodies
12. H gene with no somatic mutation
13. Molecular genetics of anti‐carbohydrate antibodies
14. Developmentally controlled expression of immunoglobulin VH genes
15. V genes encoding autoantibodies: molecular and phenotypic characteristics