111In-Labeled Nonspecific Immunoglobulin Scanning in the Detection of Focal Infection

New England Journal of Medicine

Volumn 321, Issue 14, 1989, Pages 935-940

  Rubin, Robert H ^a   Fischman, Alan J ^b   Callahan, Ronald J ^b   Khaw, Ban an ^b   Keech, Francis ^b   Ahmad, Marsood ^b   Wilkinson, Robert ^b   Strauss, H William ^b  

^a Infectious Disease Unit of the Medical Service ^*  (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSTIC AGENT; IMMUNOGLOBULIN G; INDIUM; INDIUM 111; RADIOISOTOPE;

ABDOMEN; ARTICLE; FEMALE; HUMAN; INFECTION; INFLAMMATION; MALE; MICROBIOLOGY; NEOPLASM; SCINTISCANNING; VASCULAR DISEASE; ADULT; CANCER; CANDIDA ALBICANS; FUNGUS; MAJOR CLINICAL STUDY; METHODOLOGY; MYCOPLASMA PNEUMONIAE; NONHUMAN; PNEUMOCYSTIS CARINII; PRIORITY JOURNAL; PROTOZOON;

ABDOMEN; FEMALE; FOCAL INFECTION; HUMAN; IMMUNOGLOBULIN G; INDIUM RADIOISOTOPES; INFLAMMATION; MALE; NEOPLASMS; SUPPORT, NON-U.S. GOV'T; VASCULAR DISEASES;

EID: 0024472749     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198910053211404     Document Type: Article

References (30)

1. Simon GL, Geelhoed GW. Diagnosis of intraabdominal abscesses.: a review. Am Surg 1985; 51.: 431-6.
2. Hau T, Haaga JR, Aeder MI. Pathophysiology, diagnosis, and treatment of abdominal abscesses. Curr Probl Surg 1984; 21.: 1-82.
3. Gerzof SG, Johnson WC. Radiologic aspects of diagnosis and treatment of abdominal abscesses. Surg Clin North Am 1984; 64.: 53-65.
4. Mueller PR, Simeone JF. Intraabdominal abscesses.: diagnosis by sonography and computed tomography. Radiol Clin North Am 1983; 21.: 425-43.
5. Feldberg MA, Koehler PR, van Waes PF. Psoas compartment disease studied by computed tomography.: analysis of 50 cases and subject review. Radiology 1983; 148.: 505-12.
6. Gerzon SG, Oates ME. Imaging techniques for infection in the surgical patient. Surg Clin North Am 1988; 68.: 147-65.
7. Littenberg RL, Taketa RM, Alazraki NR, Halpern SE, Ashburn WL. Gallium-67 for localization of septic lesions. Ann Intern Med 1973; 79.: 403-6.
8. Sfakianakis GN, Al-Sheikh W, Heal A, Rodman G, Zeppa R, Serafini A. Comparison of scintigraphy with In-111 leukocytes and Ga-67 in the diagnosis of occult sepsis. J Nucl Med 1982; 23.: 618-26.
9. McNeil BJ, Sanders R, Alderson PO, et al. A prospective study of computed tomography, ultrasound, and gallium imaging in patients with fever. Radiology 1981; 139.: 647-53.
10. Biello DR, Levitt RG, Melson GL. The roles of gallium-67 scintigraphy, ultrasonography, and computed tomography in the detection of abdominal abscesses. Semin Nucl Med 1979; 9.: 58-65.
11. Knochel JQ, Koehler PR, Lee TG, Welch DM. Diagnosis of abdominal abscesses with computed tomography, ultrasound, and 111In leukocyte scans. Radiology 1980; 137.: 425-32.
12. Carroll B, Silverman PM, Goodwin DA, McDougall IR. Ultrasonography and indium 111 white blood cell scanning for the detection of intraabdominal abscesses. Radiology 1981; 140.: 155-60.
13. Thakur ML. Cell labeling.: achievements, challenges, and prospects. J Nucl Med 1981; 22.: 1011-4.
14. Lawrence PF, Dries DJ, Alazraki N, Albo D Jr. Indium 111-labeled leukocyte scanning for detection of prosthetic vascular graft infection. J Vasc Surg 1985; 2.: 165-73.
15. DeLand FH, Goldenberg DH. Diagnosis and treatment of neoplasms with radionuclide-labeled antibodies. Semin Nucl Med 1985; 15.: 2-11.
16. Larson SM, Brown JP, Wright PW, Carrasquillo JA, Hellstrom I, Hellstrom KE. Imaging of melanoma with L-131-labeled monoclonal antibodies. J Nucl Med 1983; 24.: 123-9.
17. Larson SM, Carrasquillo JA, Krohn KA, et al. Localization of 111I-labeled p97-specific Fab fragments in human melanoma as a basis for radiotherapy. J Clin Invest 1983; 72.: 2101-14.
18. Halpern SE, Haindl W, Beauregard J, et al. Scintigraphy with In-111-labeled monoclonal antitumor antibodies.: kinetics, biodistribution, and tumor detection. Radiology 1988; 168.: 529-36.
19. Rubin RH, Young LS, Hansen WP, et al. Specific and nonspecific imaging of localized Fisher immunotype 1 Pseudomonas aeruginosa infection with Radio-labeled monoclonal antibody. J Nucl Med 1988; 29.: 651-6.
20. Rubin RH, Fischman AJ, Needleman M, et al. Radio-labeled, non-specific polyclonal human immunoglobulin in the detection of focal inflammation by scintigraphy.: comparison with gallium-67 citrate and technetium-99m-labeled albumin. J Nucl Med 1989; 30.: 385-9.
21. Fischman AJ, Rubin RH, Khaw BA, et al. Detection of acute inflammation with 111In-labeled nonspecific polyclonal IgG. Semin Nucl Med 1988; 18.: 335-44.
22. Krejcarek GE, Tucker KL. Covalent attachment of chelating groups to macromolecules. Biochem Biophys Res Commun 1977; 77.: 581-5.
23. Khaw BA, Mattis JA, Melincoff G, Strauss HW, Gold HK, Haber E. Monoclonal antibody to cardiac myosin.: imaging of experimental myocardial infarction. Hybridoma 1984; 3.: 11-23.
24. General safety test, USP XXI. Rockville, Md.: United States Pharmacopeial Convention, 1985.:1182-3, 1500.
25. Rauh DA. Clinical imaging guide 111In IgG for imaging inflammation/infection.: phase I results. Washington Crossing, N.J.: R.W. Johnson Pharmaceutical Research Institute, 1989.
26. Fischman AJ, Keech F, Khaw BA, et al. Clinical experience with 111In nonspecific polyclonal IgG. J Nucl Med 1988; 29.: Suppl.: 830. abstract.
27. Fischman AJ, Wilkinson R, Khaw BA, et al. Imaging of localized bacterial infections with Radio-labeled non-specific antibody fragments. J Nucl Med 1988; 29.: Suppl.: 887. abstract.
28. Jasin HE. Oxidative cross-linking of immune complexes by human polymorphonuclear leukocytes. J Clin Invest 1988; 81.: 6-15.
29. Rubin RH, Nedelman M, Wilkinson R, Callahan RJ, Khaw BA, Strauss HW. Effect of anti-inflammatory agents in Radio-labeled immunoglobulin scans for focal inflammation. J Nucl Med 1987; 28.: Suppl.: 695. abstract.
30. LaMuraglia GM, Fischman AJ, Strauss HW, et al. Utility of the indium-111 -labeled human immunoglobulin G scan for the detection of focal vascular graft infection. J Vase Surg 1989; 10.: 20-8.