Non-homologous sequences of parathyroid hormone and the parathyroid hormone related peptide bind to a commonreceptor on ros 17/2.8 cells

Endocrinology

Volumn 125, Issue 4, 1989, Pages 2215-2217

  Abou Samra, Abdul Badi ^a   Susumu, Uneno ^a   Jueppner, Harald ^a   Keutmann, Henry ^a   Potts, John T ^a   Segre, Gino V ^a   Nussbaum, R ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PARATHYROID HORMONE; PARATHYROID HORMONE DERIVATIVE; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RELATED PROTEIN; RADIOISOTOPE;

AMINO ACID SEQUENCE; ANIMAL CELL; BONE CELL; CELL CULTURE; CONTROLLED STUDY; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL; RAT;

BASE SEQUENCE; BINDING, COMPETITIVE; CELL LINE; NEOPLASM PROTEINS; PARATHYROID HORMONES; PEPTIDE FRAGMENTS; RADIOLIGAND ASSAY; RECEPTORS, CELL SURFACE; RECEPTORS, PARATHYROID HORMONE; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 0024467511     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/endo-125-4-2215     Document Type: Article

References (19)

1. Jueppner H, Abou-Samra AB, Uneno S, Gu WX, Potts Jr. JT, and Segre GV 1988 The parathyroid hormone-like peptide associated with humoral hypercalcemia of malignancy and parathyroid hormone bind to the same receptor on the plasma membrane of ROS 17/2.8 cells. J Biol Chem 263:8557
2. Orloff JJ, Wu TL, Heath HW, Brady TG, Brines ML, and Stewart AF 1989 Characterization of canine renal receptors for the parathyroid hormone-like protein associated with humoral hypercalcemia of malignancy. J Biol Chem 264:6097
3. Horiuchi N, Caulfield MP, Fisher JE, Goldman ME, McKee RL, Reagan JE, Levy JJ, Nutt RF, Rodan SB, Schofield TL, Clemens TL, and Rosenblatt M 1987 Similarity of synthetic peptide from human tumor to parathyroid hormone in vivo and _in vitro. Science 238:1566
4. Kemp BE, Moseley JM, RoddaCP, Ebeling PR, Wettenhall REH, Stapleton D, Diefenbach-Jagger H, Ure F, Michelangeli VP, Simmons HA, Raisz LG, Martin TJ 1987 Parathyroid hormone-related protein of malignancy: active synthetic fragments. Science 238:1568
5. Suva LJ, Winslow GA, Wettenhall REH, Hammonds RG, Moseley JM, Diefenbach-Jagger H, Rodda CP, Kemp BE, Rodriguez H, Chen EY, Hudson PJ, Martin TJ, Wood WI 1987 A parathyroid hormone-related protein implicated in malignancy hypercalcemia: cloning and expression. Science 237:893
6. Mangin M, Webb AC, Dreyer BE, Posillico JT, Ikeda K, Weir EC, Stewart AF, Bander NH, Milstone L, Barton DE, Francke U, Broadus AE 1988 Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy. Proc Natl Acad Sci USA 85:597
7. Nissensen RA, Strewler GJ, Stern PH, Jacobs JW, Eveloff J, Klein RF, Leung SC, Rosenblatt, M 1987 Parathyroid hormone-like protein from human renal carcinoma cells: Structural and functional homology with parathyroid hormone. J Clin Invest 80:1803
8. Rosenblatt M 1982 Structure-activity relations in the calcium-regulating peptide hormones. In: Endocrinology of Calcium Metabolism (Editor: JA Parsons), Raven Press, New York, p. 103
9. Nussbaum SR, Rosenblatt M, Potts Jr JT 1980 Parathyroid hormone-renal receptor interactions. Demonstration of two receptor binding domains. J Biol Chem 255:10183
10. Barany G, Merrifield RB 1979 Solid phase peptide synthesis In: The Peptides (Vol. 2) (Editor: E Gross and J Meienhofer), Academic Press, New York, p. 1
11. Keutmann HT, Griscom AW, Nussbaum SR, Reiner BF, Goud AN, Potts Jr JT, Rosenblatt M 1985 Rat parathyroid hormone-(1-34) fragment: renal adenylate cyclase activity and receptor binding properties in vitro. Endocrinology 117:1230
12. Shigeno C, UTraki Y, Westerberg DP, Potts Jr. JT, Segre GV 1988 Photoaffinity labeling of parathyroid hormone receptors in clonal rat osteosarcoma cells. J Biol Chem 263:3864
13. Stewart AF, Horst R, Deftos LJ, Cadman EC, Lang R, Broadus AE 1980 Biochemical evaluation of patients with cancer-associated hypercalcemia: Evidence for humoral and nonhumoral groups. N Engl J Med 303:1377
14. McKee RL, Goldman ME, Caulfield MP, DeHaven PA, Levy JJ, Nutt RF, Rosenblatt M 1989 The 7-34 fragment of human hypercalcemia factor is a partial agonist/antagonist for parathyroid hormone stimulated cAMP production. Endocrinology 122:3008
15. ChouPG, Fasraan G1974 Conformational parameters for amino acids in helical, 3-sheet, and random coil regions calculated from proteins. Biochemistry 13:221
16. Garnier J, Osguthorpe DJ, Robson B 1978 Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. J Mol Biol 120:97
17. Kaiser ET, Kezdy FJ 1984 Amphiphilic secondary structure: design of peptide hormones. Science 223:249
18. Taylor JW, Kaiser ET 1986 The structural characterization of 0 endorphin and related peptide hormones and neurotransmitters. Pharmacological Reviews 38:291
19. Nussbaum S, Beaudette N, Fasman G, Potts JT Jr., Rosenblatt M. 1985 Design of analogues of parathyroid hormone: A conformational approach. J Protein Chem 4:391