Neurotoxicity of β-N-methylamino-l-alanine (BMAA) and β-N-oxalylamino-l-alamine (BOAA) on cultured cortical neurons

Brain Research

Volumn 497, Issue 1, 1989, Pages 64-71

  Weiss, John H ^a   Koh, Jae young ^a   Choi, Dennis W ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Alzheimer's disease; Amyotrophic lateral sclerosis; Cell culture; Cortex; Dementia; Excitatory amino acid; Glutamate; N Methyl d aspartte receptor; Parkinson's disease

Indexed keywords

2 AMINO 3 METHYLAMINOPROPIONIC ACID; 2 AMINO 5 PHOSPHONOVALERIC ACID; 3 OXALYLAMINOALANINE; EXCITATORY AMINO ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; BRAIN CORTEX; CELL CULTURE; CYTOLOGY; FETUS; MOUSE; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL;

AMINO ACIDS, DIAMINO; ANIMAL; BETA-ALANINE; CELLS, CULTURED; CEREBRAL CORTEX; HISTOCYTOCHEMISTRY; MICE; NADH, NADPH OXIDOREDUCTASES; NADPH DEHYDROGENASE; RECEPTORS, GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, NEUROTRANSMITTER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0024466387     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(89)90970-0     Document Type: Article

References (37)

1. Amyotrophic lateral sclerosis, fifty cases observed on Guam
2. Structure-activity relations of excitatory amino acids on frog and rat spinal neurones
3. 3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding by the excitotoxinbeta-N-oxalyl-l-alpha, beta-diamino-propionic acid
4. Somatostatin immunoreactive neurons in the human hippocampus and cortex shown by immunogold/silver intensification on vibratome sections: coexistence with neuropeptide Y neurons, and effects in Alzheimer-type dementia
5. Glutamate neurotoxicity in cortical cell culture
6. 2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation
7. Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementia
8. Neuropathologic and clinical features of Parkinson's disease in Alzheimer's disease patients
9. Kynurenic acid inhibits synaptic and acidic amino acid-induced responses in the rat hippocampus and spinal cord
10. Neurodegenerative disorders of the western pacific: the search for mechanisms of pathogenesis
11. Parkinsonism-dementia complex, an endemic disease on the island of Guam
12. Amyotrophic lateral sclerosis and its association with dementia, parkinsonism and other neurological disorders: a review
13. Convulsions induced in 10-day-old rats by intraperitoneal injection of monosodium glutamate and related excitant amino acids
14. Quantitative determination of glutamate-mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay
15. Vulnerability of cultured cortical neurons to damage by excitotoxins: differential susceptibility of neurons containing NADPH-diaphorase
16. Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity
17. Characteristics, distribution and interrelationships of somatostatin, neuropeptide Y, and NADPH-diaphorase in human caudate nucleus
18. Third conference on toxicity of cycads — introductory remarks
19. Stereospecific acute neuronotoxicity of ‘uncommon’ plant amino acids linked to human motor-system diseases
20. Brain and retinal damage from lathyrus excitotoxin, beta-N-oxalyl-l-alpha, beta-diaminopropionic acid
21. 3H]d-AP5 binding sites in rat brain membranes
22. The neurolathyrogen, beta-N-oxalyl-l-alpha, beta-diaminopropionic acid, is a potent agonist at ‘glutamate-preferring’ receptors in the frog spinal cord
23. Neurological disorders associated with deficiency of glutamate dehydrogenase
24. Abnormal glutamate metabolism in amyotrophic lateral sclerosis
25. Amyotrophic lateral sclerosis and Parkinsonism-dementia on Guam: a 25-year prospective case-control study
26. Distribution and toxocity of alpha-amino-beta-methylaminopropionic acid
27. Specific antagonism of excitotoxic action of ‘uncommon’ amino acids assayed in organotypic mouse cortical cultures
28. Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type
29. Demonstration of a unique population of neurons with NADPH-diaphorase histochemistry
30. Discovery and partial characterization of primate motor-system toxins
31. Lathyrism: evidence for role of the neuroexcitatory amino acid BOAA
32. Guam amyotrophic lateral sclerosis-Parkinsonism-dementia linked to a plant excitant neurotoxin
33. NADPH-diaphorase: a selective histochemical marker for striatal neurons containing both somatostatin- and avian pancreatic polypeptide (AP)-like immunoreactivities
34. Central effects ofbeta-N-oxalyl-alpha, beta-diaminopropionic acid and other lathyrus factors
35. Beta-N-methylamino-l-alanine neurotoxicity: requirement for bicarbonate as a cofactor
36. Beta-N-methylamino-l-alanine (BMAA) neurotoxicity on murine cortical neurons
37. Toxicity of Cycads