Synergistic effect of thymosin α1 and αβ-interferon on NK activity in tumor-bearing mice

International Journal of Immunopharmacology

Volumn 11, Issue 5, 1989, Pages 443-450

  Favalli, Cartesio ^a   Mastino, Antonio ^a   Jezzi, Teresa ^a   Grelli, Sandro ^a   Goldstein, Allan L ^b   Garaci, Enrico ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; THYMOSIN;

MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; CHROMIUM RADIOISOTOPES; CYTOTOXICITY TESTS, IMMUNOLOGIC; INJECTIONS, INTRAPERITONEAL; INTERFERON TYPE I; KILLER CELLS, NATURAL; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; SPLEEN; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; THYMOSIN; TIME FACTORS;

EID: 0024454795     PISSN: 01920561     EISSN: None     Source Type: Journal    
DOI: 10.1016/0192-0561(89)90172-0     Document Type: Article

References (34)

1. Modulation of mouse natural killer cell activity by the serum thymic factor
2. Phase I trial of immunomodulatory activities of human leukocyte interferon in advanced cancer patients
3. Enhancement of natural killer cell activity in mice by treatment with a thymic factor
4. Increase of mouse resistance to Candida albicans infection by thymosin alpha 1
5. In vivo anti-tumor activity of combinations of interferon alpha and interleukin-2 in a murine model. Correlation of efficacy with the induction of cytotoxic cells resembling natural killer cells
6. Modulation of murine natural killer cell activity in vitro and in vivo by recombinant human interferons
7. Thymosin Fraction 5 and intensive combination chemotherapy prolonging the survival of patients with small-cell lung cancer
8. Modulation of natural killer activity by thymosin alpha 1 and interferon
9. The role of the thymus in the maintenance of natural killer cells in vivo
10. Enhanced NK cell activity in mice injected with interferon and interferon inducers
11. Thymosins
12. Systemic administration of human leukocyte interferon to melanoma patients. II. Cellular events associated with changes in natural killer cytotoxicity
13. Origin and differentiation of natural killer cells: functional and morphologic studies of purified NK-1.1 + cells
14. In vivo activities of NK cells against primary and metastic tumors in experimental animals
15. Natural cytotoxic reactivity in mouse lymphoid cells against syngeneic and allogeneic tumors. I. Distribution reactivity
16. Effect of human recombinant interferon on cytotoxic activity of natural killer (NK) cells and monocytes
17. Thymosin treatment modulates production of interferon
18. Protective activity of thymosin against opportunistic infections in animal models
19. In vitro modulation of mouse natural killer (NK) cell activity by the serum thymic factor (FTS)
20. Generation of natural killer cells from bone marrow precursors in vitro
21. Changes in the host natural killer cell population in mice during tumor development. I. Kinetics and in vivo significance
22. Modulation of NK activity by recombinant leukocyte interferon in advanced cancer patients
23. Changes in the host natural killer cell population in mice during tumor development. II. The mechanism of suppression of NK activity
24. Modulation of IL 2 dependent growth of mouse NK cells by interferon and T-lymphocytes
25. Development of hyporesponsiveness to augmentation of natural killer cell activity after multiple doses of maleicanhydride divinyl ether: association with decreased numbers of large granular lymphocytes
26. Thymic peptide hormones: basic properties and clinical applications in cancer
27. Modulation of human natural killer cell cytotoxic activity, lymphokine production, and interleukin 2 receptor expression by thymic hormones
28. Suppression of natural killer cell cytotoxicity in the peripheral blood of patients receiving interferon therapy
29. Thymic hormones: a clinical update
30. Restorative effects of thymosin polypeptides on purified derivative-dependent migration inhibition factor production by the peripheral blood lymphocytes of adult thymectomized guinea pigs
31. Biology of Disease. Human natural killer cells: biologic and pathologic aspects
32. The cytolytic and regulatory role of natural killer cells in human neoplasia
33. Thymosin alpha 1 restores NK-cell activity and prevents tumor progression in mice immunosuppressed by cytostatics or X-rays
34. Thymosin increases production of T cell growth factor by normal human peripheral blood lymphocytes