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Volumn 30, Issue 32, 1989, Pages 4263-4266

Chemistry of neocarzinostatin-mediated degradation of d(GCATGC). Mechanism of spontaneous thymine release

Author keywords

[No Author keywords available]

Indexed keywords

ZINOSTATIN;

EID: 0024450867     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(01)80706-1     Document Type: Article
Times cited : (30)

References (25)
  • 13
    • 84918600796 scopus 로고    scopus 로고
    • The order, HTP » dithiothreitol 〉 2-mercaptoethanol 〉 thiophenol, for the efficiency of NCS activation was also observed in nicking of sonicated calf thymus DNA and covalently closed circular DNA.
  • 14
    • 84918601146 scopus 로고    scopus 로고
    • 5
  • 15
    • 84918619795 scopus 로고    scopus 로고
    • 2O) δ 1.79 (m, 2 H), 2.28 (m, 1 H), 2.40, (m, 1 H), 2.48 (m, 1 H), 2.85 (m, 1 H), 2.88 (m, 2 H), 3.62 (t, J = 6.7 Hz, 2 H), 4.11 (m, 4 H), 4.16 (m, 1 H), 4.22 (m, 1 H), 4.42 (m, 1 H), 4.58 (m, 1 H), 4.99 (m, 1 H), 5.82 (d, J = 7.5 Hz, 1 H), 6.24 (t, J = 7.1 Hz, 1 H), 6.29 (t, J = 6.8 Hz, 1 H), 7.78 (d, J = 7.5 Hz, 1 H), 8.06 (s, 1 H).
  • 16
    • 84918616999 scopus 로고    scopus 로고
    • pGC) (7%) during incubation is not due to the spontaneous decomposition of 1 which has been proved to be stable under the incubation conditions, whereas alkali treatment of 1 provided thymine and d(pGC) quantitatively.
  • 17
    • 84918626024 scopus 로고    scopus 로고
    • 11
  • 20
    • 84918604807 scopus 로고    scopus 로고
    • 14
  • 22
    • 33748719327 scopus 로고
    • Mechanisms of bleomycin-induced DNA degradation
    • For discussion of the rearrangement of C-4′ hydroperoxide intermediate in bleomycin-mediated degradation of DNA, see, and references therein
    • (1987) Chemical Reviews , vol.87 , pp. 1167
    • Stubbe1
  • 23
    • 84918602771 scopus 로고    scopus 로고
    • 16


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.