메뉴 건너뛰기




Volumn 14, Issue 3, 1989, Pages 245-278

Animal models of the epilepsies

Author keywords

Animal model; Cat; Electroencephalography; Epilepsy; Monkey; Rodent

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; DIAZEPAM; ETHOSUXIMIDE; EXCITATORY AMINO ACID; KAINIC ACID; PHENOBARBITAL; PHENYTOIN; VALPROIC ACID;

EID: 0024449997     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-0173(89)90003-9     Document Type: Review
Times cited : (525)

References (332)
  • 6
    • 0020001034 scopus 로고
    • Pharmacological evidence for two kinds of GABA receptor in rat hippocampal pyramidal cells studied in vitro
    • (1982) J. Physiol. (Lond.) , vol.328 , pp. 125-141
    • Alger1    Nicoll2
  • 7
    • 0022453133 scopus 로고
    • Differential changes in the content of amino acid neurotransmitters in discrete regions of rat brain prior to the onset and during the course of homocysteine-induced seizures
    • (1986) J. Neurochem. , vol.46 , pp. 1582-1592
    • Allen1    Grieve2    Griffiths3
  • 12
    • 0023085828 scopus 로고
    • Mechanisms of generalized epilepsy with spike and wave discharges
    • 39th Edition, Elsevier
    • (1987) The London Symposium , pp. 184-190
    • Avoli1
  • 13
    • 0019963327 scopus 로고
    • Role of the thalamus in generalized penicillin epilepsy: observations on decorticated cats
    • (1982) Exp. Neurol. , vol.77 , pp. 386-402
    • Avoli1    Gloor2
  • 14
    • 0020608432 scopus 로고
    • An analysis of penicillin induced generalized spike and wave discharges using simultaneous recording of cortical and thalamic single units
    • (1983) J. Neurophysiol. , vol.50 , pp. 819-837
    • Avoli1    Gloor2    Kostopoulos3    Gotman4
  • 15
    • 0014964338 scopus 로고
    • Penicillin as an epileptogenic agent: its effect on an isolated neuron
    • (1970) Science , vol.167 , pp. 1257-1260
    • Ayala1    Vasconsetto2
  • 16
    • 0022958810 scopus 로고
    • Metabolic, morphologic and electrophysiologic profiles of human temporal lobe foci: an attempt at correlation
    • (1986) Adv. Exp. Med. Biol. , vol.203 , pp. 115-125
    • Babb1
  • 18
    • 0343233889 scopus 로고
    • The genetic animal model for reflex epilepsy in the Mongolian gerbil: differential efficacy of new anticonvulsive drugs and prototype antiepileptics
    • (1987) Pharmacol. Res. Commun. , vol.19 , pp. 429-440
    • Bartoszyk1    Hamer2
  • 19
    • 0019472821 scopus 로고
    • Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy
    • (1981) Neuroscience , vol.6 , pp. 1361-1391
    • Ben-Ari1    Tremblay2    Riche3    Ghilini4    Naquet5
  • 20
    • 0017651618 scopus 로고
    • Comparison of effects of bicuculline, strychnine, and picrotoxin and those of pentylenetetrazol on photically evoked after discharges
    • (1977) Epilepsia , vol.18 , pp. 465-470
    • Bigler1
  • 24
    • 0015799240 scopus 로고
    • Long-lasting potentiation of synaptic transmission in the dentate area of the anesthetized rabbit following stimulation of the perforant path
    • (1973) J. Physiol. (Lond.) , vol.232 , pp. 311-356
    • Bliss1    Lømo2
  • 25
    • 0017200848 scopus 로고
    • Endorphins: profound behavioral effects in rats suggest new etiological factors in mental illness
    • (1976) Science , vol.194 , pp. 630-632
    • Bloom1    Segal2    Ling3    Guillemin4
  • 27
    • 0000365269 scopus 로고
    • Experimental baso-temporal epilepsy in the cat Discrete epileptogenic lesions produced in the hippocampus or amygdaloid nucleus by tungstic acid
    • (1960) Neurology , vol.10 , pp. 546-554
    • Blum1    Liban2
  • 30
    • 84910531157 scopus 로고
    • Kindling in the rat hippocampus: studies of neurotransmitter mechanisms and transfer mechanisms
    • J.A. Wada, 2nd edn., Raven, New York
    • (1981) Kindling II , pp. 295-301
    • Burchfiel1
  • 37
    • 0023880901 scopus 로고
    • Comparative anticonvulsant activity and neurotoxicity of 4-amino-N-(2,6-dimethylphenyl)benzamide and prototype antiepileptic drugs in mice and rats
    • (1988) Epilepsia , vol.29 , pp. 198-203
    • Clark1
  • 38
  • 41
    • 0018100593 scopus 로고
    • In situ injection of kainic acid: a new method for selectively lesioning neuronal cell bodies while sparing axons of passage
    • (1978) J. Comp. Neurol. , vol.180 , pp. 301-323
    • Coyle1    Molliver2    Kuhar3
  • 43
    • 0037976653 scopus 로고
    • A new mutant causing epileptic seizures in domestic fowls
    • (1969) Poultry Sci. , vol.48 , pp. 1799
    • Crawford1
  • 44
    • 84918605882 scopus 로고    scopus 로고
    • Creutzfeldt, O. and Houchin, J., Neuronal basis of EEG waves. In A. Remond (Ed.), Handbook of Electroencephalography and Clinical Neurophysiology, Vol. 2, Part C, Elsevier, Amsterdam, 174, pp. 5–55.
  • 48
    • 0021856427 scopus 로고
    • Anticonvulsant drugs and the genetically epilepsy-prone rat
    • 22nd edn.
    • (1985) Fed. Proc. , vol.44 , pp. 2640-2644
    • Dailey1    Jobe2
  • 49
    • 0022880813 scopus 로고
    • Indices of noradrenergic function in the central nervous system of seizure-naive genetically epilepsy-prone rats
    • (1986) Epilepsia , vol.27 , pp. 665-670
    • Dailey1    Jobe2
  • 51
    • 0018356250 scopus 로고
    • Epileptogenic doses of penicillin do not reduce a monosynaptic GABA-mediated postsynaptic inhibition in the intact anesthetized cat
    • (1979) Exp. Neurol. , vol.65 , pp. 552-572
    • Davenport1    Schwindt2    Crill3
  • 52
    • 0023618953 scopus 로고
    • Flurothyl seizure thresholds in mice treated neionatally with a single injection of monosodium glutamate (MSG): evaluation of experimental parameters in fluorothyl seizure testing
    • (1987) Pharmacol. Biochem. Behav. , vol.28 , pp. 165-169
    • Dawson1    Bierkamper2
  • 53
    • 0022566932 scopus 로고
    • Basic Mechanisms of the Epilepsies: Molecular and Cellular Approaches
    • 22nd edn., Raven, New York
    • (1986) Adv. Neurol. , vol.44 , pp. 1-1096
    • Delgado-Escueta1
  • 61
    • 10144247513 scopus 로고
    • Clinical use of antiepileptic drugs
    • 22nd edn., H.H. Frey, D. Janz, Handbook of Experimental Pharmacology, Springer, Berlin
    • (1985) Antiepileptic Drugs , pp. 765-790
    • Eadie1
  • 62
    • 0023742573 scopus 로고
    • Seizure susceptibility in DBA and C57 mice: the effects of various convulsants
    • (1988) Epilepsia , vol.29 , pp. 389-395
    • Engstrom1    Woodbury2
  • 65
    • 0022515064 scopus 로고
    • Decreased effectiveness of GABA-mediated inhibition in the inferior colliculus of the genetically epilepsy-prone rat
    • (1986) Exp. Neurol. , vol.93 , pp. 145-159
    • Faingold1    Gehlbach2    Caspary3
  • 66
    • 0023882118 scopus 로고
    • Excitant amino acids and audiogenic seizures in the genetically epilepsy-prone rat.I. Afferent seizure initiation pathway
    • (1988) Exp. Neurol. , vol.99 , pp. 678-686
    • Faingold1    Millan2    Boersma3    Meldrum4
  • 67
    • 0017174623 scopus 로고
    • Parenteral penicillin in rats: an experimental model for multifocal epilepsy
    • (1976) Epilepsia , vol.16 , pp. 217-222
    • Fariello1
  • 77
    • 0021258856 scopus 로고
    • Electrophysiological mechanisms of kainic acid induced epileptiform activity in the rat hippocampal slice
    • (1984) J. Neurosci. , vol.4 , pp. 1312-1323
    • Fisher1    Alger2
  • 82
    • 0021987199 scopus 로고
    • Selective inhibition of homocysteine-induced seizures by glutamic acid diethyl ester and other glutamate esters
    • (1985) Epilepsia , vol.26 , pp. 30-36
    • Freed1
  • 89
    • 0001609466 scopus 로고
    • The relative effect of methionine sulfoximine on different species
    • (1951) J. Nutr. , vol.45 , pp. 451-458
    • Gershoff1    Elvehjem2
  • 90
    • 0023118536 scopus 로고
    • Intracellular recordings in pericruciate neurons during spike and wave discharges of feline generalized penicillin epilepsy
    • (1987) Brain Res. , vol.405 , pp. 68-79
    • Giaretta1    Avoli2    Gloor3
  • 91
    • 0019748320 scopus 로고
    • Kindling as a model of limbic epilepsy
    • (1981) Neuroscience , vol.6 , pp. 1695-1706
    • Girgis1
  • 92
    • 0018713432 scopus 로고
    • Generalized epilepsy with spike-and-wave discharge: a reinterpretation of its electrographic and clinical manifestations
    • (1979) Epilepsia , vol.20 , pp. 571-588
    • Gloor1
  • 94
    • 0017687579 scopus 로고
    • Pathophysiology of generalized penicillin epilepsy in the cat: the role of cortical and subcortical structures. II. Topical application of penicillin to the cerebral cortex and to subcortical structures
    • (1977) Electroencephalogr. Clin. Neurophysiol. , vol.43 , pp. 79-94
    • Gloor1    Quesney2    Zumstein3
  • 95
    • 0014191661 scopus 로고
    • Development of epileptic seizures through brain stimulation at low intensity
    • (1967) Nature (Lond.) , vol.214 , pp. 1020-1021
    • Goddard1
  • 99
    • 0021198486 scopus 로고
    • Penicillin spikes in rat: limitations of a single model for the study of anticonvulsants
    • (1984) Neuropharmacology , vol.23 , pp. 1001-1007
    • Golden1    Fariello2
  • 100
    • 0021128009 scopus 로고
    • The relevance of secondary epileptogenesis to the treatment of epilepsy: kindling and the mirror focus
    • (1984) Epilepsia , vol.25 , pp. S156-S168
    • Goldensohn1
  • 102
    • 0021357540 scopus 로고
    • Does the interictal EEG have a role in the diagnosis of epilepsy?
    • (1984) Lancet , vol.1 , pp. 837-838
    • Goodin1    Aminoff2
  • 103
    • 0000150288 scopus 로고
    • Tottering — a neuromuscular mutation in the mouse
    • (1962) J. Hered. , vol.53 , pp. 233-237
    • Green1    Sidman2
  • 104
    • 0343791682 scopus 로고
    • Chemically induced epileptiform seizures in the cat
    • (1963) Science , vol.142 , pp. 409-411
    • Grossman1
  • 105
    • 0016537614 scopus 로고
    • Response of generalized penicillin epilepsy in the cat to ethosuximide and diphenylhydantoin
    • (1975) Neurology , vol.25 , pp. 764-785
    • Guberman1    Gloor2    Sherwin3
  • 106
    • 0015095131 scopus 로고
    • Penicillinase and the convulsant action of penicillin
    • (1971) Neurology , vol.21 , pp. 759-764
    • Gutnick1    Prince2
  • 111
    • 0019379047 scopus 로고
    • Absence of seizures or mirror foci in experimental epilepsy after excision of alumina and astrogliotic scar
    • (1981) Epilepsia , vol.22 , pp. 107-122
    • Harris1    Lockard2
  • 112
    • 84883849002 scopus 로고
    • Cortical alterations due to methionine sulfo-ximine
    • (1964) Arch. Neurol. , vol.11 , pp. 388-407
    • Harris1
  • 113
    • 0023191483 scopus 로고
    • Limbic epilepsy induced by tetanus toxin: a longitudinal electroencephalographic study
    • (1987) Epilepsia , vol.28 , pp. 431-444
    • Hawkins1    Mellanby2
  • 114
    • 0017156720 scopus 로고
    • Inherited progressive epilepsy of the dog with comparison to Lafora's disease of man
    • 22nd edn.
    • (1976) Fed. Proc. , vol.35 , pp. 1202-1205
    • Hegreberg1    Padgett2
  • 115
    • 0001862712 scopus 로고
    • Changes in the neuronal micro-environment and epileptiform activity
    • 22nd edn., H.G. Wieser, E.-J. Speckmann, J. Engel Jr., Current Problems in Epilepsy, Libbey, London
    • (1987) The Epileptic Focus , vol.3 , pp. 27-44
    • Heinemann1
  • 116
    • 0017362119 scopus 로고
    • Extracellular free calcium and potassium during paroxysmal activity in the cerebral cortex of the cat
    • (1977) Exp. Brain Res. , vol.27 , pp. 237-243
    • Heinemann1    Lux2    Gutnick3
  • 119
    • 0015707760 scopus 로고
    • A comparative study of some convulsant substances as gamma-aminobutyric acid antagonists in the feline cerebral cortex
    • (1973) Br. J. Pharmacol. , vol.49 , pp. 37-51
    • Hill1    Simmonds2    Straughn3
  • 121
    • 0015696542 scopus 로고
    • Seizures induced by allyglycine, 3-mercaptoprioprionic acid and 4-deoxypyridine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase
    • (1973) Br. J. Pharmacol. , vol.49 , pp. 52-63
    • Horton1    Meldrum2
  • 122
    • 0022403908 scopus 로고
    • Autoradiographic localization of binding sites for the gamma-aminobutyric acid analogues 4,5,6,7-tetrahydroisoxazolo-5,4-c-pyridin-3-ol (THIP) isoguvacine and baclofen on cultured neurons of rat cerebellum and spinal cord
    • (1985) Neurosci. Lett. , vol.61 , pp. 153-157
    • Hosli1    Krogsgaard-Larsen2    Hosli3
  • 128
    • 0023732109 scopus 로고
    • The relationship between interictal and ictal paroxysms in an in vitro model of focal hippocampal epilepsy
    • (1988) Ann. Neurol. , vol.24 , pp. 591-598
    • Jensen1    Yaari2
  • 129
    • 0022779177 scopus 로고
    • Noradrenergic and serotonergic determinants of seizure susceptibility and severity in genetically epilepsy-prone rats
    • (1986) Life Sci. , vol.39 , pp. 775-782
    • Jobe1    Dailey2    Reigel3
  • 130
    • 0021350157 scopus 로고
    • Abnormalities in norepinephrine turnover rate in the central nervous system of the genetically epilepsy-prone rat
    • (1984) Brain Res. , vol.290 , pp. 357-360
    • Jobe1    Ko2    Daily3
  • 131
    • 0015837002 scopus 로고
    • Convulsions induced in 10-day-old rats by intraperitoneal injection of monosodium glutamate and related excitant amino acids
    • (1973) Biochem. Pharmacol. , vol.22 , pp. 137-140
    • Johnston1
  • 132
    • 0022636727 scopus 로고
    • Characterization of lithium potentiation of pilocarpine-induced status epilepticus in rats
    • (1986) Exp. Neurol. , vol.91 , pp. 471-480
    • Jope1    Morrisett2    Snead3
  • 133
    • 0023669077 scopus 로고
    • Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel
    • (1987) Cell , vol.50 , pp. 405-413
    • Kamb1    Iverson2    Tanouye3
  • 135
    • 0017085664 scopus 로고
    • Antiserum to brain gangliosides produces recurrent epileptiform activity
    • (1976) Science , vol.194 , pp. 735-737
    • Karpiak1    Graf2    Rapport3
  • 137
    • 0022501358 scopus 로고
    • Isolation of neurons suitable for patch-clamping from adult mammalian central nervous system
    • (1986) J. Neurosci. Meth. , vol.16 , pp. 227-238
    • Kay1    Wong2
  • 140
    • 84977246821 scopus 로고
    • Paroxysmal responses to intermittent light stimulation in a population of baboons (Papio papio)
    • (1966) Epilepsia , vol.7 , pp. 215-219
    • Killam1    Naquet2    Bert3
  • 142
    • 4244203490 scopus 로고
    • Acute strychnine-induced seizures in cats: a Golgi study
    • (1975) Epilepsia , vol.791-792 , pp. 523-526
    • Knopman1
  • 144
    • 0022592897 scopus 로고
    • Neuronal sensitivity to GABA and glutamate in generalized epilepsy with spike and wave discharges
    • (1986) Exp. Neurol. , vol.92 , pp. 20-36
    • Kostopoulos1
  • 145
    • 0020637094 scopus 로고
    • Participation of cortical recurrent inhibition in the genesis of spike and wave discharges in feline generalized penicillin epilepsy
    • (1983) Brain Res. , vol.267 , pp. 101-112
    • Kostopoulos1    Avoli2    Gloor3
  • 146
    • 84918613255 scopus 로고    scopus 로고
    • Krauss, G.L., Kaplan, P. and Fisher, R.S., Parenteral magnesium sulfate fails to control electroshock and pentylenetetrazol seizures in mice, Epilepsy Res., in press.
  • 147
    • 0002734928 scopus 로고
    • Amygdaloid kindling in the rat: regional differences and general properties
    • J.A. Wada, Raven, New York
    • (1981) Kindling II , pp. 31-47
    • La Salle1
  • 148
    • 0021235221 scopus 로고
    • Neurotransmitter abnormalities in genetically epileptic rodents
    • 22nd edn.
    • (1984) Fed. Proc. , vol.43 , pp. 2505-2509
    • Laird1    Dailey2    Jobe3
  • 149
  • 150
    • 0021346298 scopus 로고
    • Chronic failure of inhibition of the CA1 area of the hippocampus following kainic acid lesions of the CA3/4 area
    • (1984) Brain Res. , vol.295 , pp. 317-324
    • Lancaster1    Wheal2
  • 151
    • 0019027054 scopus 로고
    • Neuronal activity in chronic ferric chloride epileptic foci in cats and monkey
    • (1980) Epilepsia , vol.21 , pp. 251-254
    • Lange1    Neafsey2    Wyler3
  • 153
    • 0002734928 scopus 로고
    • Amygdaloid kindling in the rat: regional differences and general properties
    • J.A. Wada, Raven, New York
    • (1981) Kindling II , pp. 31-47
    • LaSalle1
  • 158
    • 0023858306 scopus 로고
    • Patch-clamp techniques for time-resolved capacitance measurements in single cells
    • (1988) Eur. J. Physiol. , vol.411 , pp. 137-146
    • Lindau1    Neher2
  • 163
    • 0023897574 scopus 로고
    • Which animal models should be used in the search for new antiepileptic drug? A proposal based on experimental and clinical considerations
    • (1988) Epilepsy Res. , vol.2 , pp. 145-181
    • Löscher1    Schmidt2
  • 168
    • 0017647010 scopus 로고
    • Pentelenetetrazol and penicillin are selective antagonists of GABA-medi-ated post-synaptic inhibition in cultured mammalian neurons
    • (1977) Nature (Lond.) , vol.267 , pp. 720-721
    • MacDonald1    Barker2
  • 170
    • 0023751686 scopus 로고
    • Generalized convulsions induced by pentylenetetrazol in the cat: participation of forebrain, brainstem and spinal cord
    • (1988) Epilepsia , vol.29 , pp. 379-388
    • Magistris1    Mouradian2    Gloor3
  • 171
    • 0021066462 scopus 로고
    • Value of Mongolian gerbils in antiepileptic drug evaluation
    • (1983) Epilepsia , vol.24 , pp. 609-615
    • Majkowski1    Kaplan2
  • 173
    • 0014302712 scopus 로고
    • Bilateral symmetrical epileptonic foci in monkey cerebral cortex: mechanisms of interactions and regional variations in capacity for synchronous spike slow wave discharges
    • (1968) Arch. Neurol. , vol.19 , pp. 99-116
    • Marcus1    Watson2
  • 174
    • 0013964827 scopus 로고
    • Effects of steroids on cerebral electrical activity: epileptogenic effects of conjugated estrogens and related compounds in the cat and rabbit
    • (1966) Arch. Neurol. , vol.15 , pp. 521-532
    • Marcus1    Watson2    Goldman3
  • 177
    • 0015394379 scopus 로고
    • A permanent change in convulsive threshold in normal and brain-damaged rats with repeated small doses of pentelenetetrazole
    • (1972) Epilepsia , vol.13 , pp. 663-674
    • Mason1    Cooper2
  • 183
    • 9544231078 scopus 로고
    • Metabolic response in vitro to electrical stimulation of sections of mammalian brain
    • (1951) Biochem. J. , vol.49 , pp. 382-393
    • McIlwain1
  • 184
    • 0022878542 scopus 로고
    • Status epilepticus following stimulation of a kindled hippocampal focus in intact and commissurotomized rats
    • (1986) Exp. Neurol. , vol.94 , pp. 554-570
    • McIntyre1    Stokes2    Edson3
  • 185
    • 0021744681 scopus 로고
    • Kindling: an animal model of complex partial epilepsy
    • (Suppl.)
    • (1984) Ann. Neurol. , vol.16 , pp. 72-76
    • McNamara1
  • 186
    • 0016682771 scopus 로고
    • Attempts to produce spike and wave complexes in the electrocortico-gram of the rat
    • (1975) Epilepsia , vol.16 , pp. 295-299
    • McQueen1    Woodbury2
  • 187
    • 0010323575 scopus 로고
    • Preclinical test systems for evaluation of novel compounds
    • 22nd edn., B.S. Meldrum, R.J. Porter, Current Problems in Epilepsy, Libbey, London
    • (1986) New Anticonvulsant Drugs , vol.4 , pp. 31-48
    • Meldrum1
  • 188
    • 0022922647 scopus 로고
    • Benzodiazepine receptors and their relationship to epilepsy
    • (1986) Epilepsia , vol.27 , pp. S3-S13
    • Meldrum1    Chapman2
  • 189
    • 0015238873 scopus 로고
    • Convulsive effects of 4-deoxypyridoxine and of bicuculline in photosensitive baboons (Papio papio) and in rhesus monkeys (Macaca mulatta)
    • (1971) Brain Res. , vol.35 , pp. 419-436
    • Meldrum1    Horton2
  • 190
    • 0016138845 scopus 로고
    • Epileptic brain damage in adolescent baboons following seizures induced by allylglycine
    • (1974) Brain , vol.97 , pp. 407-418
    • Meldrum1    Horton2    Brierly3
  • 191
    • 0023198906 scopus 로고
    • Redistribution of transmitter amino acids in rat hippocampus and cerebellum during seizures induced by l-allylglycine and bicuculline: and immunocytochemical study with antisera against conjugated GABA, glutamate and aspartate
    • (1987) Neuroscience , vol.22 , pp. 17-27
    • Meldrum1    Swan2    Ottersen3    Storm-Mathisen4
  • 197
    • 0023880243 scopus 로고
    • Excitant amino acids and audiogenic seizures in the genetically epilepsy-prone rat. II. Efferent seizure propagating pathways
    • (1988) Exp. Neurol. , vol.99 , pp. 687-698
    • Millan1    Meldrum2    Boersma3    Faingold4
  • 198
    • 0022637029 scopus 로고
    • Induction of audiogenic seizure susceptibility by focal infusion of excitant amino acid or bicuculline into the inferior colliculus of normal rats
    • (1986) Exp. Neurol. , vol.91 , pp. 634-639
    • Millan1    Meldrum2    Faingold3
  • 200
    • 0022827021 scopus 로고
    • Anterior thalamic mediation of generalized pentylenetetrazol seizures
    • (1986) Brain Res. , vol.399 , pp. 212-223
    • Mirski1    Ferrendelli2
  • 201
    • 0023138497 scopus 로고
    • nterruption of the connections of the mammillary bodies protects against generalized pentylenetetrazol seizures in guinea pigs
    • (1987) J. Neurosci. , vol.7 , pp. 662-670
    • Mirski1    Ferrendelli2
  • 202
    • 84918601707 scopus 로고
    • Effect of naloxone infusion on rate of epileptiform discharges in patients with complex partial seizures
    • (1988) Epilepsia , vol.29 , pp. 698
    • Molaie1    Kadzielawa2
  • 204
    • 33846242234 scopus 로고
    • Secondary epileptogenic lesions
    • (1960) Epilepsia , vol.1 , pp. 538-560
    • Morrell1
  • 205
    • 0023222060 scopus 로고
    • Effects of drugs on the initiation and maintenance of status epilepticus induced by administration of pilocarpine to lithium-pretreated rats
    • (1987) Exp. Neurol. , vol.97 , pp. 193-200
    • Morrisett1    Jope2    Snead3
  • 206
    • 0023605861 scopus 로고
    • Status epilepticus is produced by administration of cholinergic agonists to lithium-treated rats: comparison with kainic acid
    • (1987) Exp. Neurol. , vol.98 , pp. 594-605
    • Morrisett1    Jope2    Snead3
  • 208
    • 0019882992 scopus 로고
    • Kainic acid as a tool for the study of temporal lobe epilepsy
    • (1981) Life Sci. , vol.29 , pp. 2031-2042
    • Nadler1
  • 213
    • 0018294249 scopus 로고
    • Analysis of inherited epilepsy using single locus mutations in mice
    • (1979) Fed. Proc. , vol.38 , pp. 2405-2410
    • Noebels1
  • 214
    • 0021231817 scopus 로고
    • A single gene error of noradrenergic axon growth synchronizes central neurones
    • (1984) Nature (Lond.) , vol.310 , pp. 409-411
    • Noebels1
  • 215
    • 0017362948 scopus 로고
    • 14C]penicillin during experimental focal epilepsy in cat neocortex
    • (1977) Brain Res. , vol.125 , pp. 293-303
    • Noebels1    Pedley2
  • 216
    • 0018416478 scopus 로고
    • Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering
    • (1979) Science , vol.204 , pp. 1334-1336
    • Noebels1    Sidman2
  • 217
    • 0017717302 scopus 로고
    • The hippo-campal slice: a model system for studying the pharmacology of seizures and for screening anticonvulsant drugs
    • (1977) Epilepsia , vol.18 , pp. 543-548
    • Oliver1    Hoffer2    Wyatt3
  • 218
    • 0016230519 scopus 로고
    • Kainic acid: a powerful neurotoxic analog of glutamate
    • (1974) Brain Res. , vol.77 , pp. 501-512
    • Olney1    Rhee2    Ho3
  • 219
    • 0019731736 scopus 로고
    • The GABA postsynaptic membrane receptor-ionophore complex. Site of action of convulsant and anticonvulsant drugs
    • (1981) Mol. Cell. Biochem. , vol.39 , pp. 261-279
    • Olsen1
  • 220
    • 0023225798 scopus 로고
    • Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila
    • (1987) Science , vol.237 , pp. 749-753
    • Papazian1    Schwarz2    Tempel3    Jan4    Yan5
  • 222
  • 223
    • 0020549621 scopus 로고
    • Zinc-induced seizures: a new experimental model of epilepsy
    • (1983) Epilepsia , vol.24 , pp. 169-176
    • Pei1    Zhao2    Huang3    Cao4
  • 227
    • 0017862965 scopus 로고
    • Experimental epileptogen-esis: kindling — induced epilepsy in rats
    • (1978) Exp. Neurol. , vol.58 , pp. 190-202
    • Pinel1    Rovner2
  • 228
    • 0022511816 scopus 로고
    • Role of excitatory amino acid transmission in the genesis of seizures elicited from the deep prepiriform cortex
    • (1986) Brain Res. , vol.377 , pp. 205-210
    • Piredda1    Gale2
  • 229
    • 0021988085 scopus 로고
    • Intracerebral site of convulsant action of bicuculline
    • (1985) Life Sci. , vol.36 , pp. 1295-1298
    • Piredda1    Lim2    Gale3
  • 231
    • 0014326425 scopus 로고
    • Experimental spike and wave responses in petit mal epilepsy
    • (1968) Epilepsia , vol.9 , pp. 221-232
    • Pollen1
  • 235
    • 0014319622 scopus 로고
    • The depolarization shift in ‘epileptic’ neurons
    • (1968) Exp. Neurol. , vol.21 , pp. 467-485
    • Prince1
  • 237
    • 0000856128 scopus 로고
    • ‘Centrencephalic’ spike-wave discharges following parenteral penicillin injection in the cat
    • (1969) Neurology , vol.19 , pp. 309-310
    • Prince1    Farrell2
  • 239
  • 246
    • 0018722492 scopus 로고
    • Histopathology of the ferric-induced chronic epileptic focus in cats and monkey
    • (1979) Exp. Neurol. , vol.66 , pp. 205-210
    • Reid1    Sypert2    Boggs3
  • 247
    • 0022780332 scopus 로고
    • The genetically epilepsy-prone rat: an overview of seizure-prone characteristics and responsiveness to anticonvulsant drugs
    • (1986) Life Sci. , vol.39 , pp. 763-774
    • Reigel1    Dailey2    Jobe3
  • 248
    • 0023939524 scopus 로고
    • Responsiveness of genetically epilepsy-prone rats to intracerebroventricular morphine-induced convulsions
    • (1988) Life Sci. , vol.42 , pp. 1743-1749
    • Reigel1    Jobe2    Dailey3    Stewart4
  • 251
    • 0022779360 scopus 로고
    • Anatomical changes of the GABAergic system in the inferior colliculus of the genetically epilepsy-prone rat
    • (1986) Life Sci. , vol.39 , pp. 789-798
    • Roberts1    Ribak2
  • 255
    • 0018130714 scopus 로고
    • Effect of n-dipropylacetate on amino acid concentrations in the mouse brain: correlations with anticonvulsant activity
    • (1978) J. Neurochem. , vol.31 , pp. 1325-1327
    • Scheeter1    Tranier2    Grove3
  • 256
    • 0016640871 scopus 로고
    • Characteristics of CA1 neurons recorded intracellularly in the hippocampal slice
    • (1975) Brain Res. , vol.85 , pp. 423-435
    • Schwartzkroin1
  • 258
    • 0022922287 scopus 로고
    • Spontaneous rhythmic synchronous activity in epileptic human and normal monkey temporal lobe
    • (1986) Epilepsia , vol.27 , pp. 523-533
    • Schwartzkroin1    Haglund2
  • 259
  • 261
    • 0016799448 scopus 로고
    • Long-lasting facilitation of a synaptic potential following tetanization in the in vitro hippocampal slice
    • (1975) Brain Res. , vol.89 , pp. 107-119
    • Schwartzkroin1    Wester2
  • 263
    • 0022839332 scopus 로고
    • Epileptic seizures in rats homozygous for two mutations, zitter and tremor
    • (1986) J. Hered. , vol.77 , pp. 441-444
    • Serikawa1    Yamada2
  • 264
    • 0023930845 scopus 로고
    • Electrophysiological actions of norepinephrine in rat lateral hypothalamus.I. Norepinephrine-induced modulation of LH neuronal responsiveness to afferent synaptic inputs and putative neurotransmitters
    • (1988) Brain Res. , vol.446 , pp. 77-89
    • Sessler1    Cheng2    Waterhouse3
  • 265
    • 0021848553 scopus 로고
    • A review of mouse mutants as genetic models of epilepsy
    • (1985) Epilepsia , vol.26 , pp. 143-150
    • Seyfried1    Glaser2
  • 266
    • 0023712337 scopus 로고
    • Guide to neurochemical analysis of surgical specimens of human brain
    • (1988) Epilepsy Research , vol.2 , pp. 281-288
    • Sherwin1
  • 267
    • 0023129330 scopus 로고
    • Decreased hippocampal inhibition and a selective loss of interneurons in experimental epilepsy
    • (1987) Science , vol.235 , pp. 73-76
    • Sloviter1
  • 268
    • 0017843943 scopus 로고
    • Gamma-hydroxybutyrate in the monkey. I. Electroencephalographic, behavioral and pharmacoki-netic studies
    • (1978) Neurology , vol.28 , pp. 636-642
    • Snead1
  • 269
    • 0017840956 scopus 로고
    • Gamma-hydroxybutyrate in the monkey. II. Effect of chronic oral anticonvulsant drugs
    • (1978) Neurology , vol.28 , pp. 643-648
    • Snead1
  • 270
    • 0021459012 scopus 로고
    • Ontogeny of gamma-hydroxybutyric acid. II. Electroencephalographic effects
    • (1984) Dev. Brain Res. , vol.15 , pp. 89-96
    • Snead1
  • 271
    • 0023780307 scopus 로고
    • Gamma-hydroxybutyrate model of generalized absence seizures: further characterization and comparison with other absence models
    • (1988) Epilepsia , vol.29 , pp. 361-368
    • Snead1
  • 272
    • 0019209463 scopus 로고
    • Anticonvulsants specific for petit mal antagonize epileptogenic effect of leucine enkephalin
    • (1980) Science , vol.210 , pp. 1031-1033
    • Snead1    Bearden2
  • 273
    • 0021266791 scopus 로고
    • The ontogeny of seizures induced by leucine-enkephalin and β-endorphin
    • (1984) Ann. Neurol. , vol.15 , pp. 594-598
    • Snead1    Stephens2
  • 274
    • 0041352655 scopus 로고
    • Quantitative determination of the convulsive reactivity by electrical stimulation of the brain with the skull intact
    • (1937) J. Lab. Clin. Med. , vol.22 , pp. 1274-1276
    • Spiegel1
  • 277
    • 0014718915 scopus 로고
    • Convulsant actions of tetrazole derivatives
    • (1970) Pharmacology , vol.3 , pp. 367-370
    • Stone1
  • 285
    • 0021321698 scopus 로고
    • Behavioral alterations associated with generalized spike and wave discharges in the EEG of the cat
    • (1984) Exp. Neurol. , vol.83 , pp. 167-186
    • Taylor-Courval1    Gloor2
  • 288
    • 0023334886 scopus 로고
    • Gene dosage and complementation analysis of the Shaker locus in Drosophila
    • (1987) J. Neurosci. , vol.7 , pp. 1307-1317
    • Timpe1    Jan2
  • 290
    • 0022004129 scopus 로고
    • Endogenous anticonvulsant substance in rat cerebral spinal fluid following a generalized seizure
    • (1985) Science , vol.228 , pp. 1106-1107
    • Tortella1    Long2
  • 291
    • 0021929786 scopus 로고
    • Endogenous opioid systems: physiological role in the self-limitation of seizures
    • (1985) Brain Res. , vol.15 , pp. 174-178
    • Tortella1    Long2    Holaday3
  • 293
    • 0020079720 scopus 로고
    • Cellular mechanisms of neuronal synchronization in epilepsy
    • (1982) Science , vol.216 , pp. 745-747
    • Traub1    Wong2
  • 294
  • 297
  • 300
    • 0014816798 scopus 로고
    • The effect of methionine sulphoximine on the incorporation of labelled glucose acetate phenylalanine and proline into glutamate and related amino acids in the brains of mice
    • (1970) Journal of Neurochemistry , vol.17 , pp. 985-991
    • Vanden Berg1    Vanden Velden2
  • 301
    • 0023092227 scopus 로고
    • Contributions of basic neurochemistry towards a novel concept of epilepsy
    • (1987) Neurochem. Res. , vol.12 , pp. 111-119
    • van Gelder1
  • 304
    • 0023267678 scopus 로고
    • Electrical stimulation of the centromedian thalamic nucleus in the treatment of convulsive seizures: a preliminary report
    • (1987) Epilepsia , vol.28 , pp. 421-430
    • Velasco1    Velasco2    Ogarrio3    Fanghanel4
  • 306
    • 0023186191 scopus 로고
    • A model of status epilepticus based on electrical stimulation of hippocampal afferent pathways
    • (1987) Exp. Neurol. , vol.96 , pp. 681-691
    • Vicedomini1    Nadler2
  • 307
    • 0017684787 scopus 로고
    • Pharmacological prophylaxis in the kindling model of epilepsy
    • (1977) Arch. Neurol. , vol.34 , pp. 389-395
    • Wada1
  • 309
    • 0017889115 scopus 로고
    • Secondary generalized convulsive seizures induced by daily amygdaloid stimulation in rhesus monkeys
    • (1978) Neurology , vol.28 , pp. 1026-1036
    • Wada1    Mizoguchi2    Osawa3
  • 310
    • 0015459632 scopus 로고
    • Longitudinal correlative analysis of epileptic baboon, Papio papio
    • (1972) Neurology , vol.22 , pp. 1272-1285
    • Wada1    Terao2    Booker3
  • 312
    • 0023802851 scopus 로고
    • Response of status epilepticus induced by lithium and pilocarpine to treatment with diazepam
    • (1988) Exp. Neurol. , vol.101 , pp. 267-275
    • Walton1    Treiman2
  • 313
    • 0023871894 scopus 로고
    • Experimental secondarily generalized convulsive status epilepticus induced by d,l-homocysteine thiolactone
    • (1988) Epilepsy Res. , vol.2 , pp. 79-86
    • Walton1    Treiman2
  • 318
    • 0014167019 scopus 로고
    • Cellular behavior in secondary epileptogenic lesions
    • (1967) Neurology , vol.17 , pp. 1193-1204
    • Wilder1    Morrell2
  • 319
    • 0018167668 scopus 로고
    • Recurrent seizure induced by cortical iron injection, a model of post-traumatic epilepsy
    • (1978) Ann. Neurol. , vol.4 , pp. 329-333
    • Willmore1
  • 320
    • 0041999447 scopus 로고
    • Common synaptic effects of pentylenetetrazol and penicillin
    • (1974) Brain Res. , vol.116 , pp. 217-249
    • Wilson1    Escueta2
  • 322
    • 0018425019 scopus 로고
    • Dendritic mechanisms underlying penicillin-induced epileptiform activity
    • (1979) Science , vol.204 , pp. 1228-1231
    • Wong1    Prince2
  • 324
    • 0015074391 scopus 로고
    • The comparative effects of various hydrazides on gamma-aminobutyric acid and its metabolism
    • (1971) J. Neurochem. , vol.18 , pp. 1017-1025
    • Wood1    Abrahams2
  • 325
    • 0020366190 scopus 로고
    • The effects of local application of homocysteine on neuronal activity in the central nervous system of the rat
    • (1982) Life Sci. , vol.31 , pp. 2683-2691
    • Wuerthele1    Yasuda2    Freed3    Hoffer4
  • 326
    • 0020063206 scopus 로고
    • Neurons in human epileptic cortex: correlation between unit and EEG activity
    • (1982) Ann. Neurol. , vol.11 , pp. 301-308
    • Wyler1    Ojemann2    Ward3
  • 327
    • 0019869105 scopus 로고
    • Neurons in human epileptic cortex: response to direct cortical stimulation
    • (1981) J. Neurosurg. , vol.55 , pp. 904-908
    • Wyler1    Ward2
  • 328
    • 0015324394 scopus 로고
    • Intracellular study of seizure-like after discharges elicited in thin hippocampal sections in vitro
    • (1972) Exp. Neurol. , vol.35 , pp. 154-164
    • Yamamoto1
  • 329
    • 0013993489 scopus 로고
    • Electrical activities in thin sections from the mammalian brain maintained in chemically-defined media in vitro
    • (1966) J. Neurochem. , vol.13 , pp. 1333-1343
    • Yamamoto1    McIlwain2
  • 332
    • 0023218260 scopus 로고
    • The GABA agonist THIP, attenuates antinociception in the mouse by modifying central cholinergic transmission
    • (1987) Neuropharmacology , vol.26 , pp. 433-437
    • Zorn1    Enna2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.