Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis

Cell

Volumn 58, Issue 6, 1989, Pages 1075-1084

  McMahon, Andrew P ^a   Moon, Randall T ^b  

^a HOFFMANN LA ROCHE INC   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION; HISTOLOGY; NONHUMAN; ONCOGENE; ONCOGENE INT 1; OOCYTE; PRIORITY JOURNAL; TOAD;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; CLONING, MOLECULAR; DNA; EMBRYO, NONMAMMALIAN; MICE; MOLECULAR SEQUENCE DATA; NERVOUS SYSTEM; OOCYTES; PHENOTYPE; PROTEIN SORTING SIGNALS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION, GENETIC; TRANSLATION, GENETIC; XENOPUS;

EID: 0024435879     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(89)90506-0     Document Type: Article

References (38)

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2. 35S-label as an aid to rapid DNA sequence determination
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6. A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus
7. Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis
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10. Changes in the expression of α-fodrin during embryonic development of Xenopus laevis
11. Antisense RNA inhibits expression of membrane skeleton protein 4.1 during embryonic development of Xenopus
12. Microinjection of synthetic Xhox-1A homeobox mRNA disrupts somite formation in developing Xenopus embryos
13. Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development
14. Effects of altered expression of the neural cell adhesion molecule, N-CAM, on early neural development in Xenopus embryos
15. Monoclonal antibodies to the cells of a regenerating limb
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17. Tissuespecific expression of distinct spectrin and ankyrin transcripts in erythroid and non-erythroid cells
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19. A C-terminal signal prevents secretion of luminal ER proteins
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21. The activation of cellular oncogenes by retroviral insertion
22. The int genes in mammary tumorigenesis and in normal development
23. Mutations affecting segment number and polarity in Drosophila
24. Precursor of egg white lysozyme
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26. Transfection of the int-1 mammary oncogene in cuboidal RAC mammary cell line results in morphological transformation and tumorigenicity
27. The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless
28. Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing
29. Expression of the protooncogene, int-1, is restricted to postmeiotic male sperm cells and the neural tube of mid-gestational embryos
30. Cell lineage labels and region specific markers in the analysis of inductive interactions
31. Uber induktion von Embryonenanlagen durch Implantation artfremder Organisatonen
32. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
33. Structure and nucleotide sequence of the putative mammary oncogene int-1, proviral insertions leave the protein-encoding domain intact
34. Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless
35. Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo
36. Improved M13 phage cloning vectors and host strains: nucleotide sequences of M13mp18 and pVC19 vectors