Geography and the Clinical Picture of Sickle Cell Disease: An Overview

Annals of the New York Academy of Sciences

Volumn 565, Issue 1, 1989, Pages 109-119

  SERJEANT, G R ^a  

^a UNIVERSITY OF THE WEST INDIES   (Jamaica)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN;

ENVIRONMENTAL FACTOR; GEOGRAPHY; GHANA; HAPLOTYPE; HEREDITY; HUMAN; PRIORITY JOURNAL; SHORT SURVEY; SICKLE CELL ANEMIA; SUDAN; UNITED STATES;

ANEMIA, SICKLE CELL; FETAL HEMOGLOBIN; GEOGRAPHY; GLOBINS; HAPLOTYPES; HETEROZYGOTE; HUMAN; MALARIA;

EID: 0024435695     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1989.tb24157.x     Document Type: Article

References (53)

1. Peculiar elongated and sickle‐shaped red blood corpuscles in a case of severe anemia
2. Sickle cell anemia
3. Case of sickle cell anaemia in the Sudan
4. A case of sickle cell anaemia
5. Uber die Sickelzellanamie
6. Sickling phenomenon in northern Greece
7. Sickle‐cell trait in southern India
8. Sickle cell trait in India: a review of known distribution
9. Distribution of sickle‐cell hemoglobin in Saudi Arabia
10. Glucose‐6‐phosphate dehydrogenase deficiency, the sickling trait, and malaria in Saudi Arab children
11. Incidence of hemoglobin S carriers in Sicily
12. Sickle‐cell trait in south Turkey
13. Sickle cell disease in Israel. Report of 5 cases in an Arab family
14. Mild sickle‐cell anaemia in Iran associated with high levels of fetal haemoglobin
15. Distribution of the sickle cell gene. A new light on the origin of the East Africans
16. Origin of the sickling gene
17. Migrant populations and the diffusion of the sickle‐cell gene
18. Evidence for the multicentric origin of the sickle cell hemoglobin gene in Africa
19. Multiple origins of the sickle mutation: evidence from beta° globin gene cluster polymorphisms
20. Origin of the beta°‐globin gene in Blacks: the contribution of recurrent mutation or gene conversion or both
21. Aγ chains: variations due to anomalies at the molecular level
22. A genetic marker for elevated levels of haemoglobin F in homozygous sickle cell disease
23. High fetal hemoglobin production in sickle cell anemia in the Eastern Province of Saudi Arabia is genetically determined
24. Hematological observations on Arabian SS patients with a homozygosity or heterozygosity for a β° chromosome with haplotype #31
25. Sickle cell disease in Orissa State, India
26. The origin of the sickle mutation in Greece; evidence from β globin gene cluster polymorphisms
27. Beta° gene in Sicily is in linkage disequilibrium with the Benin haplotype: implications for gene flow
28. Sickle cell anaemia among Eti‐Turks: haematological, clinical and genetic observations
29. Haplotypes and alpha globin gene analyses in sickle cell anaemia patients from Kenya
30. Hematologically and genetically distinct forms of sickle cell anemia in Africa
31. Fetal hemoglobin levels and beta' globin haplotypes in an Indian population with sickle cell disease
32. Concurrent sickle‐cell anemia and alpha‐thalassemia. Effect on severity of anemia
33. The interaction of alpha‐thalassemia and homozygous sickle‐cell disease
34. Effects of thalassemia and microcytosis on the hemologic and vaso occlusive severity of SS anemia
35. Alpha‐thalassemia is related to prolonged survival in sickle cell anemia
36. Increased HbF in sickle cell anemia is determined by a factor linked to the beta° gene from one parent
37. Production of F cells in sickle cell anemia: regulation by a genetic locus of loci separate from the beta‐globin gene cluster
38. Lack of influence of fetal hemoglobin levels or erythrocyte indices on the severity of sickle cell anemia
39. Levels of fetal hemoglobin necessary for treatment of sickle cell disease
40. Heterogeneity of sickle‐cell anemia based on a profile of hematological variables
41. The effect of HbF and alpha‐thalassemia on the red cell indices in sickle cell anemia
42. The haematology of steady state homozygous sickle cell disease: interrelationships between haematological indices
43. Irreversibly sickled cells and splenomegaly in sickle‐cell anaemia
44. Delayed skeletal maturation in sickle cell anemia in Jamaica
45. Body habitus of Jamaican adults with sickle cell anemia
46. Delayed menarche in homozygous sickle cell disease: a search for prognostic factors
47. Fetal hemoglobin and clinical severity of homozygous sickle cell disease in early childhood
48. The diagnosis and management of sickle cell anaemia
49. The effect of malaria chemoprophylaxis on spleen size in sickle‐cell anaemia
50. Effect of environment on sickle cell disease in West Africa: epidemiologic and clinical considerations
51. The sickle cell diseases
52. A comparative study of the morbidity associated with sickle cell anemia among patients in Ibadan (Nigeria) and Oakland (USA)
53. The molecular basis of alpha thalassemia in India. Its interaction with the sickle cell gene