Stimulation of the periaqueductal gray matter inhibits nociception at the supraspinal as well as spinal level

Brain Research

Volumn 502, Issue 1, 1989, Pages 61-66

  Morgan, Michael M ^a   Sohn, Jin Hun ^a   Liebeskind, John C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antinociception; Ascending pain modulation; Descending pain modulation; Hot plate test; Periaqueductal gray; Stimulation produced analgesia; Tail flick test

Indexed keywords

ANALGESIA; ANIMAL EXPERIMENT; BRAIN INJURY; ELECTROSTIMULATION; MALE; NOCICEPTION; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; SPINAL CORD;

ANIMAL; ELECTRIC STIMULATION; MALE; PAIN; PERIAQUEDUCTAL GRAY; RATS; RATS, INBRED STRAINS; SPINAL CORD; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0024433959     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(89)90461-7     Document Type: Article

References (33)

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8. Characterization of the spinal adrenergic receptors mediating the spinal effects produced by the microinjection of morphine into the periaqueductal gray
9. Evidence for opioid and non-opioid forms of stimulation-produced analgesia in the rat
10. Inhibition of spinal neuronal responses to noxious skin heating by stimulation of mesencephalic periaqueductal gray in the cat
11. Inhibition of the spinal transmission of nociceptive information by supraspinal stimulation in the cat
12. An autoradiographic study of projections ascending from the midbrain central gray, and from the region lateral to it, in the rat
13. The use of microknives in brain lesion studies and the production of isolated brain-stem islands
14. Spinal monoamine and opiate systems partly mediate the antinociceptive effects produced by glutamate at brainstem sites
15. Low dose of morphine microinjected in the ventral periaqueductal gray matter of the rat depresses responses of nociceptive ventrobasal thalamic neuron
16. Neuronal loss in the ventrobasal complex of the rat thalamus alters behavioral responses to noxious stimulation
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21. Natural mechanisms of pain inhibition
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23. N. raphe magnus lesions disrupt stimulation-produced analgesia from ventral but not dorsal midbrain areas in the rat
24. Reversible inactivation of raphe magnus neurons: effects on nociceptive threshold and morphine-induced analgesia
25. Time-course of alterations in morphine-induced analgesia and nociceptive threshold following medullary raphe lesions
26. Dorsal raphe stimulation modulates nociceptive responses in thalamic parafascicular neurons via an ascending pathway: further studies on ascending pain modulation pathways
27. Surgery in the rat during electrical analgesia induced by focal brain stimulation
28. Periventricular system lesions and stimulation-produced analgesia
29. Spinal pathways mediating tonic or stimulation-produced descending inhibition from the periaqueductal gray or nucleus raphe magnus are separate in the cat
30. Midbrain stimulation inhibits tail-flick only at currents sufficient to excite rostral medullary neurons
31. Systematic examination in the rat of brain sites sensitive to the direct application of morphine: observation of differential effect within the periaqueductal gray