EFFECTS OF ENDOTHELIUM-DERIVED NITRIC OXIDE ON PERIPHERAL ARTERIOLAR TONE IN MAN

The Lancet

Volumn 334, Issue 8670, 1989, Pages 997-1000

  Vallance, Patrick ^a   Collier, Joe ^a   Moncada, Salvador ^b  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b WELLCOME RESEARCH LABORATORIES   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 N ETHYLARGININE; ACETYLCHOLINE; GLYCERYL TRINITRATE; NITRIC OXIDE; UNCLASSIFIED DRUG;

ADULT; BLOOD FLOW; FEMALE; HUMAN; HUMAN EXPERIMENT; INTRAARTERIAL DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL; VASODILATATION;

ACETYLCHOLINE; ADULT; ARGININE; BRACHIAL ARTERY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION; ENDOTHELIUM, VASCULAR; FEMALE; FOREARM; HUMAN; INFUSIONS, INTRA-ARTERIAL; MALE; MUSCLE TONUS; NITRIC OXIDE; NITROGLYCERIN; OMEGA-N-METHYLARGININE; REGIONAL BLOOD FLOW; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; VASODILATION;

EID: 0024428094     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(89)91013-1     Document Type: Article

References (22)

1. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
2. Paradoxical vasoconstriction produced by acetylcholine m atherosclerotic coronary arteries
3. The loss of endothelium-dependent vascular relaxation in hypertension
4. Nitric oxide accounts for the biological activity of endothelium-derived relaxing factor
5. Vascular endothelial cells synthesise nitric oxide from L-arginine
6. L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation
7. Role of endothelium-derived nitric oxide m the regulation of blood pressure
8. The measurement of volume changes m human limbs
9. Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of nitric oxide formation
10. G-Methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo?
11. Local inhibition of converting enzyme and vascular responses to angiotensin and bradykinin in the human forearm
12. Endogenous prostaglandins as local regulators of blood flow in man effect of indomethacin on reactive and functional hyperaemia
13. The effect of intra-arterial antihistamines on the hyperaemia following temporary arrest of the circulation in the human forearm
14. Effects of 5-hydroxytryptamine and ketanserin on the forearm vascular resistance in man
15. The discovery of nitric oxide as the endogenous nitrovasodilator
16. The role of endothelium in the responses of vascular smooth muscle to drugs
17. Flow-induced release of endothelium-denved relaxing factor
18. EDRF coordinates the behaviour of vascular resistance vessels
19. Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholesterolemia and atherosclerosis
20. Impairment of endothelium-dependent relaxation and changes in levels of cyclic GMP m aorta from streptozotocin-induced diabetic rats
21. Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium