Attenuating effects of diazepam on the electroretinogram of normal humans

Retina

Volumn 9, Issue 3, 1989, Pages 216-225

  Jaffe, Myles Jay ^a,b   Hommer, Dan W ^b   Caruso, Rafael C ^a   Straw, Greg M ^b   de Monasterio, Francisco M ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Attenuation; Benzodiazepine; Dopamine; GABA; Ganzfeld electroretinogram

Indexed keywords

DIAZEPAM;

DARK ADAPTATION; DOPAMINERGIC SYSTEM; ELECTRORETINOGRAM; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; LIGHT ADAPTATION; NORMAL HUMAN;

ADULT; COMPARATIVE STUDY; DARK ADAPTATION; DIAZEPAM; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRORETINOGRAPHY; HUMAN; MALE; OSCILLOMETRY; PHOTORECEPTORS; RANDOM ALLOCATION; RETINA; TIME FACTORS;

EID: 0024426246     PISSN: 0275004X     EISSN: 15392864     Source Type: Journal    
DOI: 10.1097/00006982-198909030-00010     Document Type: Article

References (36)

1. Pourcho RG. Autoradiographic localization of 3H muscimol in the cat retina. Brain Res 1981;215:187-199.
2. Mosinger JM, Yazulla S. Colocalization of GAD-like im- munoreactivity and 3H-GABA uptake in amacrine cells of rabbit retina. J Comp Neurol 1985;240:396-406.
3. Agardh E, Ehinger B. Retinal GABA neuron labelling with 3H isoguvacine in different species. Exp Eye Res 1983;36:215- 229.
4. Brandon C. Retinal GABA neurons: Localization in vertebrate species using an antiserum to rabbit brain glutamate decarboxylase. Brain Res 1985;344:286-295.
5. Nishimura Y, Schwartz ML, Rakic P. GABA and GAD im- munoreactivity of photoreceptor terminais in primate retina. Nature 1986;320:753-756.
6. Mariani AP, Caserta MT. Electron microscopy of glutamate decarboxylase (GAD) immunoreactivity in the inner plexiform layer of the rhesus monkey retina. J Neurocytol 1986; 15:645- 655.
7. Guidotti A, Toffano G, Costa E. An endogenous protein modulates the affinity of GABA and benzodiazepine receptors in rat brain. Nature 1978;275:553-555.
8. Mariani AP, Cosenza-Murphy D, Barker JL. GABAergic synapses and benzodiazepine receptors are not identically distributed in the primate retina. Brain Res 1987;415:153-157.
9. Marshbum PB, Iuvone PM. The role of GABA in the regulation of the dopamine/tyrosine hydroxylase-containing neurons of the rat retina. Brain Res 1981;214:335-347.
10. Kamp CW, Morgan WW. Benzodiazepines suppress the light response to retinal dopaminergic neurons in vivo. Eur J Pharmacol 1982;77:343-346.
11. Kramer S. Dopamine: A retinal neurotransmitter. I. Retinal uptake, storage, and light-stimulated release of 3-H dopamine in vivo. Invest Ophthalmol Vis Sci 1971;10:438-452.
12. Bauer B. Photic release of radioactivity from rabbit retina preloaded with 3H GABA. Acta Ophthalmol 1978;56:270-283.
13. Wachtmeister L, Dowling J. The oscillatory potentials of the mudpuppy retina. Invest Ophthalmol Vis Sci 1978;17:1176-1188.
14. Hommer K. Die Wirkung des Chinins, Chlorochins, Jodac- etats und Chlordiazepoxids auf das ERG der isolierten Kan- inchennetzhauL Albrecht Graefes Arch Klin Exp Ophthal 1968;175:111-120.
15. Tallman JF, Paul SM, Skolnick P, Gallager D. Receptors of the age of anxiety: pharmacology of the benzodiazepines. Science 1980;207:274-281.
16. Jaffe MJ, Hommer D, Caruso RC, Karson CN, de Monasterio FM. Effects of diazepam on the human ganzfeld electroretinogram. Invest Ophthalmol Vis Sci 1986;27:232 (Abstr).
17. Jaffe MJ, Levinson PD, Zimmlichman R. Coen JC, Karson CN, de Monasterio FM. The effect of metoclopramide on the ganzfeld electroretinogram. Vision Res 1987;27:1693-1700.
18. Gunkel RD, Bergsma D, Gouras P. A ganzfeld stimulator for electroretinography. Arch Ophthalmol 1976;94:669-670.
19. Berson E, Gouras P, Gunkel RD. Rod responses in retinitis pigmentosa, dominantly inherited. Arch Ophthalmol 1968;80:58-70.
20. Norren D, Padmos P. Human and macaque blue cones studied with electroretinography. Vision Res 1973;13:1241-1254.
21. Algevere P, Westbeck S. Human ERG in response to double flashes of light during the course of dark-adaptation: A Fourier analysis of the oscillatory potentials. Vision Res 1972; 12:195- 214.
22. Greenblatt DJ, Shader RI, Divoll M, Harmatz JS. Benzodiazepines: A summary of pharmacokinetic properties. Br J Clin Pharm 1981:11:11S-16S.
23. Jaffe MJ, Hommer DW. Attenuating actions of diazepam on the photomyoclonic reflex. Retina 1987;7:237-240.
24. Gouras P. Electroretinopathy: Some basic principles. Inv Ophthalmol Vis Sci 1970;9:557-569.
25. Massof RW, Wu L, Finkelstein D, Perry C, Starr SJ, Johnson MA. Properties of electroretinographic intensity-response functions in retinitis pigmentosa. Doc Ophthalmol 1984;57:279- 296.
26. Schuurmans RP, Zrenner E. Responses of the blue sensitive cone system from the visual cortex and the arterially perfused eye in cat and monkey. Vision Res 1981;21:1611-1615.
27. Fulton AB, Rushton WA. The human rod ERG: Correlation with psychophysical responses in light and dark adaptation. Vision Res 1978;18:793-800.
28. Heynen H, Wachtmeister L, van Norren D. Origin of the oscillatory potentials in the primate retina. Vision Res 1985; 25:1365-1373.
29. Heynen H, van Norren D. Origin of the electroretinogram in the intact macaque eye. L Vision Res 1985:25:697- 707.
30. Redbum DA, Kyles C, Ferkany J. Subcellular distribution of GABA receptors in bovine retina. Exp Eye Res 1979:28:525- 532.
31. Penn R, Hagins W. Signal transmission along retinal rods and the origin of the electroretinographic a-wave. Nature 1969:223:201 -205.
32. Brann M, Jelsema C. Dopamine receptors on photoreceptor membranes couple to a GTP-binding protein which is sensitive to both pertussis and cholera toxin. Biochem Biophys Comm 1985;133:222-227.
33. Grace AA, Bunney BS. Paradoxical GABA excitation of nigral dopaminergic cells: Indirect mediation through reticulata inhibitory neurons. Eur J Pharmacol 1979;59:211-218.
34. Ross RJ, Waszczak B, Lee EK, Walters JR. Effects of benzodiazepines on single unit activity in the substantia nigra pars reticulata. Life Sci 1982;31:1025-1035.
35. Hakoc JN, Mariani AP. Tyrosine hydroxylase immunoreactivity in the rhesus monkey retina reveals synapses from bipolar cells to dopaminergic amacrine cells. J. Neuroscience 1987;7:2785- 2793.
36. Johnson MA, Sergiu M, Elman MJ, McPhee TJ. Neovascularization in central retinal venous occlusion: Electroretinographic findings. Archiv Ophthalmol 1988;106:348-356.