Interindividual variation among humans in carcinogen metabolism, dna adduct formation and dna repair

Carcinogenesis

Volumn 10, Issue 9, 1989, Pages 1563-1566

  Harris, Curtis C ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN;

CANCER RISK; CHEMICAL CARCINOGENESIS; DNA ADDUCT; DNA REPAIR; EDITORIAL; HEREDITY; HUMAN; METABOLISM;

CARCINOGENS; CELL TRANSFORMATION, NEOPLASTIC; DNA; DNA REPAIR; HUMAN; MODELS, BIOLOGICAL; NEOPLASMS;

EID: 0024423728     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/10.9.1563     Document Type: Note

References (55)

1. Cleaver, J.D., Bodell WJ., Gruenert, D.C., Kapp, L.N., Kaufman, W.K., Park, S.D. and Zelle, B. (1982) Repair and replication abnormalities in various human hypersensitive diseases. In Harris, C.C. and Cerutti, P.A. (eds), Mechanisms of Chemical Carcinogenesis. Alan R.Liss, New York, pp. 409-416.
2. Caitwrigit, R.A., Glasham, R.W., Rogers, HJ., Ahmad, R.A., Baiham-Hall, D., Higgins, E. and Kahn, M.A. (1982) Role of N-acetyltransferase phenotypes in bladder carcinogenesis: A pharmacogenetic epidemiological approach to bladder cancer. Lancet, 2, 842-845.
3. Ayesh, R., Idle J.R., Ritchie, J.C., Crothers MJ., and Hetzel, M.R. (1984) Metabolic oxidation phenotypes as markers for susceptibility to lung cancer. Nature, 312, 169-170.
4. Barbacid, M. (1986) Oncogenes and human cancer: Cause or consequence. Carcinogenesis, 7, 1037-1042.
5. Bishop, J.M. (1988) The molecular genetics of cancer: 1988. Leukemia, 2, 199-208.
6. Weinstein, I.B. (1988) The origins of human cancer: Molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment: twenty-seventh G.H.A.Clowes Memorial Award Lecture. Cancer Res., 48, 4135-4143.
7. Harris, C.C. (1987) Human tissues and cells in carcinogenesis research. Cancer Res., 47, 1-10.
8. Topal, M.D. (1988) DNA repair, oncogenes and carcinogenesis. Carcinogenesis, 9, 691-69.
9. Hanawalt, P.C. (1987) Preferential DNA repair in expressed genes. Environ. Health Perspect., 76, 9-14
10. Mattes, W.B., Hartley J.A., Kohn, K.W. and Matheson, D.W. (1988) GC- rich regions in genomes as targets for DNA alkylation. Carcinogenesis, 9, 2065-2072.
11. Dolan, M.E., Oplinger, M. and Pegg, A.E. (1988) Sequence specificity of guanine alkylation and repair. Carcinogenesis, 9, 2139-2143.
12. Guengerich, F.P. (1989) Characterization of human microsomal cytochrome P-450 enzymes. Anna. Rev. Pharmacol. Toxicol., 29, 241-264.
13. Conney, A.H. (1982) Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons. G.H.A.Clowes Memorial Lecture. Cancer Res., 42, 4875-4917.
14. Manchester, D.K. and Jacoby, E.H. (1981) Sensitivity of human placental monooxygenase activity to maternal smoking. Clin. Pharmacol. Ther., 30, 687-692.
15. Fujino, T., Gottlieb, K., Manchester, D.K., Park, S.S., West, D., Gurtoo, H.L., Tarone, R.E. and Gelboin, H.V. (1984) Monoclonal antibody phenotyping of interindividual differences in cytochrome P-450-dependent reactions of single and twin human placenta. Cancer Res., 44, 3916-3923.
16. Nowak, D., Schmidt-Preuss, U., Jorres, R., Liebke, F. and Rudiger, H.W. (1988) Formation of DNA adducts and water-soluble metabolites of benzo- [a]pyrene in human monocytes is genetically controlled. Ini. J. Cancer, 41, 169-173.
17. Kouri, R.E., McKinney, C.E., Slomiany, D.J., Snodgrass, D.R., Wray, N.P. and McLemore, T.L. (1982) Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes. Cancer Res., 42, 5030-5037.
18. Trell, L., Korsgaard, R., Janzon, L. and Trell, E. (1985) Distribution and reproducibility of aryl hydrocarbon hydroxylase inducibility in a prospective population study of middle-aged male smokers and nonsmokers. Cancer, 56, 1988-1994.
19. Hawke, L.J. and Farrell, G.C. (1986) Increased binding of benzo(a]pyrene metabolites to lymphocytes from patients with lung cancer. Cancer Lett., 30, 289-297.
20. Kaisaty, A., Smith, P., Jaczq, E., McAllister, C.B., Wilkinson, G.R., Ray, W.A. and Branch, R.A. (1987) Genetic predisposition to bladder cancer ability to hydroxylate debrisoquine and mephenytoin as risk factors. Cancer Res., 47, 5488-5493.
21. Idle, J.R., Mahgoub, A., Sloan, T.P., Smith, R.L., Mbanefo, C.O. and Baba- bunmi, E.A. (1981) Some observations on the oxidation phenotype status of Nigerian patients presenting with cancer. Cancer Lett., 11, 331-338.
22. Lang, N.P., Chu, D.Z., Hunger, C.F., Kendall, D.C., Flammang, T.J. and Kadlubar, F.F. (1986) Role of aromatic amine acetyltransferase in human colorectal cancer. Arch. Surg., 121, 1259-1261.
23. Petruzzelli, S., Camus, A.M., Carrozzi, L., Ghelarducci, L., Rindi, M., Menconi, G., Angeletti, C.A., Ahotupa, M., Hietanen, E., Aitio A., Saracci, R., Bartsch, H. and Giutini, C. (1988) Long-lasting effects of tobacco smoking on pulmonary drug-metabolizing enzymes: A case-control study on hmg cancer patients. Cancer Res., 48, 4695-4700.
24. De Flora, S., Petruzzelli, S., Camoirano, A., Bennicelli, C., Romano, M., Rindi, M., Ghelarducci, L. and Giutini, C. (1987) Pulmonary metabolism of mutagens and its relationship with lung cancer and smoking habits. Cancer Res., 47, 4740-4745.
25. Harries, G.C., Boobis, A.R., Collier, N. and Davies, D.S. (1986) Interindividual differences in the activation of two hepatic carcinogens to mutagens by human liver. Hum. Toxicol., 5, 21-26.
26. Minchin, R.F., McManus, M.E., Boobis, A.R., Davies, D.S. and Thorgeirsson, S.S. (1985) Polymorphic metabolism of the carcinogen 2-acetyl- aminofluorene in human liver microsomes. Carcinogenesis, 6, 1721-1724.
27. Siegfried, J.M., Rudo, K., Bryant, B.J., Ellis, S., Mass, M.J. and Nesnow, S. Metabolism of benzo[a]pyrene in monolayer cultures of human bronchial epithelial cells from a series of donors. Cancer Res., 46, 4368-4371.
28. Autrup, H. and Harris, C.C. (1983) Metabolism of chemical carcinogens by cultured human tissues. In Harris, C.C. and Autrup, H. (eds), Human Carcinogenesis. Academic Press, New York, pp. 169-194.
29. Pelkonen, O. and Nebert, D.W. (1982) Metabolism of polycyclic aromatic hydrocarbons: Etiologic role in carcinogenesis. PharmacoL Rev., 34, 189-222.
30. Daniel, F.B., Stoner, G.D. and Schut, H.A.J. (1983) Interindividual variation in the DNA binding of chemical genotoxins following metabolism by human bladder and bronchus explants. In DeSerres.F J. and Pero, R. (eds), Individual Susceptibility to Genotoxic Agents in Human Population. Plenum Press, New York, pp. 177-199.
31. Yoo, J.S., Guengerich, F.P. and Yang, C.S. (1988) Metabolism of /V-nitroso- dialkylamines by human liver microsomes. Cancer Res., 48, 1499-1504.
32. Gamer, R.C., Martin, C.N. and Clayson, D.B. (1984) Carcinogenic aromatic amines and related compounds in chemical carcinogens. In Searle, A. (ed.), Chemical Carcinogens. American Chemical Society, Washington, DC, pp. 175-276.
33. Stowers, S.J. and Anderson, M.W. (1985) Formation and persistence of benzo- [ajpyrene metabolite—DNA adducts. Environ. Health Perspect., 61, 31-39.
34. Sterner, G.D., Daniel, F.B., Schenck, K.M., Schut, H.A., Sandwisch, D.W. and Gohara, A.F. (1982) DNA binding and adduct formation of aflatoxin B, in cultured human and animal tracheobronchial and bladder tissues Carcinogenesis, 3, 1345-1348.
35. Vahakangas, K., Autrup, H. and Harris, C.C. (1984) Intenndividual variation in carcinogen metabolism, DNA damage and DNA repair. In Berlin, A., Draper, M., Hemminki, K. and Vainio, H. (eds), Monitoring Human Exposure to Carcinogenic and Mutagenic Agents. IARC Scientific Publications, Lyon, pp. 85-98.
36. Kuroki, T., Hosomi, J., Chida, K., Hosoi I., and Nemoto, N. (1987) Interindividual variations of arylhydrocarbon-hydroxyase activity in cultured human epidermal and dermal cells. Gann, 78, 45-53.
37. Ftrera, F.P., Santella, R.M., Brenner, D., Poirier, M.C., Munshi, A.A., Fischman, H.K. and Van Ryzin, J. (1987) DNA adducts, protein adducts, and sister chromatid exchange in cigarette smokers and nonsmokers. J. Natl. Cancer Inst., 79, 449-456.
38. Setlow, R.B. (1983) Variations in DNA repair among humans. In Harris, C.C. and Autrup, H. (eds). Human Carcinogenesis, Academic Press, New York, pp. 231-254.
39. Pfero, R.W, Johnson, D.B., Markowitz, M., Doyle, G., Lund-Pero, M., Seidegard, J., Halper, M. and Miller, D.G. (1989) DNA repair synthesis in individuals with and without a family history of cancer. Carcinogenesis, 10, 693-697.
40. Pero, R.W., Bryngelsson, C., Bryngelsson, T. and Norden, A. (1983) A genetic component of the variance of W-acetoxy-2-acetylaminofluorene-induced DNA damage in mononuclear leukocytes determined by a twin study. Hum. Genet., 65, 181-184.
41. D’Ambrosio, S.M., Samuel, M.J., Dutta-Choudhury, T.A. and Wani, A.A.: O-Methylguanine-DNA methyltransferase in human fetal tissues: fetal and maternal factors. Cancer Res., 47, 51-55.
42. D’Ambrosio, S.M., Wani, G., Samuel, M. and Gibson-D’Ambrosio, R.E. (1984) Repair of G-methylguanine in human fetal brain and skin cells in culture. Carcinogenesis, 5, 1657-1661.
43. Gerson, S.L., Miller, K. and Berger, N.A. (1985) O-Alkylguanine-DNA alkyltransferase activity in human myeloid cells. J. Clin. Invest., 76, 2106-2114.
44. Lawley, P.D., Harris, G., Phillips, E., Irving, W., Colaco, C.B., Lydyard, P.M. and Roitt, I.M. (1986) Repair of chemical carcinogen-induced damage in DNA of human lymphocytes and lymphoid cell lines—studies of the kinetics of removal of methylguanine and 3-methyladenine. Chem. -BioL Interactions, 57, 107-121.
45. Grafstrom, R.C., Pegg, A.E., Trump, B.F. and Harris, C.C. (1984) O6- Alkylguanine-DNA alkyltransferase activity in normal tissues and cells. Cancer Res., 44, 2855-2857.
46. Yarosh, D.B. (1985) The role of C-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis. Mutat. Res., 145, 1-16.
47. Mymes, B., Giercksky, K.E. and Krokan, H. (1983) Interindividual variation in the activity of C^-methyl guanine-DNA methyltransferase and uracil-DNA glycosylase in human organs. Carcinogenesis, 4, 1565-1568.
48. Jensen, L. and Linn, S. (1988) A reduced rale of bulky DNA adduct removal is coincident with differentiation of human neuroblastoma cells induced by nerve growth factor. Mol. Cell Biol., 8, 3964-3968.
49. Sagher, D., Karrison, T., Schwartz, J.L., Larson, R., Meier, P and Strauss, B. Low 06-alkylguanine DNA alkyltransferase activity in the peripheral blood lymphocytes of patients with therapy-related acute nonlymphocytic leukemia. Cancer Res., 48, 3084-3089.
50. Rudiger, H.W., Schwartz, U., Serrand, E., Stief, M., Krause, T., Nowak, D., Doeijer, G. and Lehnert, G. (1989) Reduced C-methylguanine repair in fibroblast cultures from patients with lung cancer. Carcinogenesis, in press.
51. Oesch, F., Aulmann, W., Platt, K.L. and Doeijer, G. (1987) Individual differences in DNA repair capacities in man. Arch. Toxicol., Suppl., 10, 172-179.
52. Skoda, R.C., Gonzalez, F.J., Detnierre, A. and Meyer, U.A. (1988) Two mutant alleles of the human cytochrome P-450dbl gene (P450C2D1) associated with genetically deficient metabolism of debrisoquine and other drugs. Proc. NalL Acad. Sci. USA, 85, 5240-5243.
53. Van Duin, M., de Wit, J., Odijk, H., Westerveld, A., Yasui, A., Koken H.M., Hoeijmakers, J.H. and Bootsma, D. (1986) Molecular characterization of the human excision repair gene ERCC-1: CDNA cloning and amino acid homology with the yeast DNA repair gene RADIO. Cell, 44, 913-923.
54. Percra, F.P. and Weinstein, I.B. (1982) Molecular epidemiology and carcinogen-DNA adduct detection: New approaches to studies of human cancer causation. J. Chronic. Dis., 35, 581-600.
55. Harris, C.C., Weston, A., Willey, J.C., Trivers, G.E. and Mann, D.L. (1987) Biochemical and molecular epidemiology of human cancer: Indicators of carcinogen exposure, DNA damage and genetic predisposition. Environ. Health Perspect., 75, 109-119.