Cultured human langerhans cells resemble lymphoid dendritic cells in phenotype and function

Journal of Investigative Dermatology

Volumn 93, Issue 5, 1989, Pages 600-609

  Romani, Nikolaus ^c   Lenz, Angela ^c   Glassel, Herta ^a   Stössel, Hella ^c   Stanzl, Ursula ^c   Majdic, Otto ^b   Fritsch, Peter ^c   Schuler, Gerold ^c  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; CELL CULTURE; DENDRITIC CELL; HISTOCHEMISTRY; LANGERHANS CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SKIN;

EID: 0024422360     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12319727     Document Type: Article

References (66)

1. Wolff K. Stingl G. The Langerhans Cell J Invest Dermatol 80 1983 17 21
2. Steinman R.M. Inaba K. Schuler G. Witmer M. Stimulation of the immune response: contributions of dendritic cells R.M. Steinman R.J. North Mechanisms of Host Resistance to Infectious Agents, Tumors, and Allografts 1986 Rockefeller University Press New York 71 97
3. Steinman R.M. Inaba K. Antigen presentation by dendritic cells B. Pernis S.C. Silverstein H.J. Vogel Processing and Presentation of Antigens 1988 Academic Press New York 167 177
4. Cohn Z.A. The macrophage-versatile element of inflammation The Harvey Lecture Series 77 1983 63 80
5. Schuler G. Inaba K. Witmer M. Steinman R. The immunologic properties of epidermal Langerhans cells B. Pernis S. Silverstein H.J. Vogel Processing and Presentation of Antigens 1988 Academic Press New York 179 184
6. Schuler G. Steinman R.M. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro J Exp Med 161 1985 526 546
7. Inaba K. Schuler G. Witmer M.D. Valinsky J. Atassi B. Steinman R.M. Immunologic properties of purified epidermal Langerhans cells. Distinct requirements for stimulation of unprimed and sensitized T lymphocytes J Exp Med 164 1986 605 613
8. Witmer-Pack M.D. Olivier W. Valinsky J. Schuler G. Steinman R.M. Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells J Exp Med 166 1987 1484 1498
9. Heufler C. Koch F. Schuler G. Granulocyte-macrophage colony-stimulating factor and interleukin-1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells J Exp Med 167 1988 700 705
10. Juhlin L. Shelley W.B. New staining techniques for the Langerhans cell Acta Derm Venereol 57 1977 289 296
11. Cooper K.D. Breathnach S.M. Caughman S.W. Palini A.G. Waxdal M.J. Katz S.I. Fluorescence microscopic and flow cytometric analysis of bone marrow-derived cells in human epidermis: a search for the human analogue of the murine dendritic Thy-1+ epidermal cell J Invest Dermatol 85 1985 546 552
12. Wolff K. Winkelmann R.K. Quantitative studies on the Langerhans cell population of guinea pig epidermis J Invest Dermatol 48 1967 504 513
13. Chaker M.B. Tharp M.D. Bergstresser P.R. Rodent epidermal Langerhans cells demonstrate greater histochemical specificity for ADP than for ATP and AMP J Invest Dermatol 82 1984 496 500
14. Li C.Y. Lam K.W. Lam L.T. Esterases in human leukocytes J Histochem Cytochem 21 1973 1 12
15. Steinman R.M. Inaba K. Stimulation of the primary mixed leukocyte reaction CRC Crit Rev Immunol 5 1985 331 348
16. Klinkert W.E.F. LaBadie J.H. O'Brien J.P. Beyer C.F. Bowers W.E. Rat dendritic cells function as accessory cells and control the production of a soluble factor required for mitogenic responses of T cells Proc Natl Acad Sci USA 77 1980 5414 5418
17. Young J.W. Strinman R.M. Accessory cell requirements for the mixed leukocyte reaction and polyclonal mitogens, as studied with a new technique for enriching blood dendritic cells Cell Immunol 111 1988 167 182
18. Van Voorhis W.C. Valinsky J. Huffman E. Luban J. Hair L.S. Steinman R.M. Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication J Exp Med 158 1983 174 191
19. Romani N. Stingl G. Tschachler E. Witmer M.D. Steinman R.M. Shevach E.M. Schuler G. The Thy-1-bearing cell of murine epidermis. A distinctive leukocyte perhaps related to natural killer cells J Exp Med 161 1985 1368 1383
20. Poulter L.W. Campbell D.A. Munro C. Janossy G. Discrimination of human macrophages and dendritic cells by means of monoclonal antibodies Scand J Immunol 24 1986 351 357
21. Hsu S.-M. Yang K. Jaffe E.S. Phenotypic expression of Hodgkin's and Reed-Sternberg cells in Hodgkin's disease Amer J Pathol 118 1985 209 217
22. McMichael AJ (ed.); uucocyte T yping Ill: White Cell Differentiation Antigens. Oxford Universiry Press. Odoed. 1988, p 1050
23. Knapp W (ed.): Leukocyu' T yping IV: White Cdl Differentiation Antigens. Oxford University Press. Oxford. in press
24. Groh V. Tschachler E. Romani N. Wolff K. Stingl G. Tac expression by cultured human Langerhans cells (abstr) J Invest Dermatol 87 1986 142
25. Steinman R.M. Schuler G. Romani N. Kaplan G. Dendritic Cells D. Zucker-Franklin M.F. Greaves C.E. Grossi A.M. Marmont Atlas of Blood Cells-Function and Pathology 1 1988 E.E edi-ermes and Lea and Febiger Philadelphia 361 377
26. Groh V. Yokozeki H. Yokoyama W.M. Foster C.A. Koning F. Brenner M.B. Stingl G. T cell receptors gamma/delta on dendritic cells of the human epidermis (abstr) J Invest Dermatol 90 1988 565
27. Groh V. Yokozeki H. Yokoyama W.M. Koning F. Foster C.A. Stingl G. The human epidermis harbors CD1+/CD3+/TCR gamma+/ HLA-DR+ dendritic cells (abstr) J Invest Dermatol 90 1988 241
28. Stingl G. Koning F. Yamada H. Yokoyama W.M. Tschachler E. Bluestone J.A. Steiner G. Samelson L.E. Lew A.M. Coligan J.E. Shevach E.M. Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain Proc Natl Acad Sci USA 84 1987 4586 4591
29. Murphy G.F. Messadi D. Fonferko E. Hancock W.W. Phenotypic transformation of macrophages to Langerhans cells in the skin Amer J Pathol 123 1986 401 406
30. Wood G.S. Turner R.R. Shiurba R.A. Eng L. Warnke R.A. Human dendritic cells and macrophages-In situ immunophenotypic definition of subsets that exhibit specific morphologic and microenvironmental characteristics Amer J Pathol 119 1985 73 82
31. Groh V. Gadner H. Radaszkiewicz T. Rappersberger K. Konrad K. Wolff K. Stingl G. The phenorypic spectrum of histiocytosis X cells J Invest Dermatol 90 1988 441 447
32. Franklin W.A. Mason D.Y. Pulford K. Falini B. Bliss E. Garter K.C. Stein H. Clarke L.C. McGee JO'D. Immunohistological analysis of human mononuclear phagocytes and dendritic cells by using monoclonal antibodies Lab Invest 54 1986 322 335
33. Witmer-Pack M.D. Valinsky J. Olivier W. Steinman R.M. Quantitation of surface antigens on cultured murine epidermal Langerhans cells: rapid and selective increase in the level of surface MHC products J Invest Dermatol 90 1988 387 394
34. Shimada S. Caughman S.W. Sharrow S.O. Stephany D. Katz S.I. Enhanced antigen-presenting capacity of cultured Langerhans' cells is associated with markedly increased expression of Ia antigen J Immunol 139 1987 2551 2556
35. Sugita K. Majdic O. Stockinger H. Holter W. Köller U. Peschel Ch. Knapp W. Use of a cocktail of monoclonal antibodies and human complement in selective killing of acute lymphocytic leukemia cells Int J Cancer 37 1986 351 357
36. Hart D.N.J. McKenzie J.L. Isolation and characterization of human tonsil dendritic cells J Exp Med 168 1988 157 170
37. Tew J.G. Thorbecke G.J. Steinman R.M. Dendritic cells in the immune response: Characteristics and recommended nomenclature (A report from the Reticulo-endothelial Society Committee on Nomenclature) J Reticuloendothel Soc 31 1982 371 380
38. Hoefsmit E.C.M. Duijvestijn A.M. Kamperdijk E.W.A. Relation between Langerhans cells, veiled cells, and interdigitating cells Immounobiology 161 1982 255 265
39. Dezutter-Dambuyant C. Cordier G. Schmitt D. Faure M. Laquoi C. Thivolet J. Quantitative evaluation of two distinct cell populations expressing HLA-DR antigens in normal human epidermis Br J Dermatol 111 1984 1 11
40. Kolde G. Knop J. Different cellular reaction patterns of epidermal Langerhans cells after application of contact sensitizing, toxic, and tolerogenic compounds. A comparative ultrastructural and morphometric time-course analysis J Invest Dermatol 89 1987 19 23
41. Macatonia S.E. Knight S.C. Edwards A.J. Griffiths S. Fryer P. Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate J Exp Med 166 1987 1654 1667
42. Zvaifler N.J. Steinman R.M. Kaplan G. Lau L.L. Rivelis M. Identification of immunostimulatory dendritic cells in the synovial effusions of patients with rheumatoid arthritis J Clin Invest 76 1985 789 800
43. Quaranta V. Majdic O. Stingl G. Liszka H. Hönigsmann H. Knapp W. A human Ia cytoplasmic determinant located on multiple forms of invariant chain (γ, γ2, γ3) J Immunol 132 1984 1900 1905
44. Knapp W. Majdic O. Stockinger H. Bettelheim P. Liszka K. Koller U. Peschel Ch. Monoclonal antibodies to human myelomonocyte differentiation antigens in the diagnosis of acute myetoid leukemia Med Oncol Tumor Pharmacother 4 1984 257 262
45. Majdic O. Liszka K. Lutz D. Knapp W. Myeloid differentiation antigen defined by a monoclonal antibody Blood 58 1981 1127 1133
46. Macher B.A. Buchler J. Scudder P. Knapp W. Feizi T. A novel carbohydrate differentiation antigen on fucogangliosides of human myeloid cells recognized by monoclonal antibody VIM-2 J Biol Chem 263 1988 10186 10191
47. Majdic O. Bettelheim P. Srockinger H. Aberer W. Liszka K. Lutz D. Knapp W. M2, a novel myelomonocytic cell surface antigen and its distribution on leukemic cells Int J Cancer 33 1984 617 623
48. Knapp W. Majdic O. Bettelheim P. Liszka K. VIL-A1, a monoclonal antibody reactive with acute lymphatic leukemia cells Leuk Res 6 1982 137 147
49. Knapp W. Majdic O. Bettelheim P. Liszka K. Aberer W. Sringl G. Typing of leukemic cells with monoclonal antibodies Ann N Y Acad Sci 420 1983 251 260
50. Groh V. Tani M. Harter A. Wolff K. Stingl G. Leu-3/T4 expression on epidermal Langerhans cells in normal and diseased skin J Invest Dermatol 86 1986 115 120
51. Wu Y.-J. Tian W.-T. Snider R.M. Rittershaus C. Rogers P. LaManna L. Ip S.H. Signal transduction of gamma/delta T cell antigen receptor with a novel mitogenic anti-delta antibody J Immunol 141 1988 1476 1479
52. Band H. Hochstenbach F. McLean J. Hata S. Krangel M.S. Brenner M.B. Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit Science 238 1987 682 684
53. Anderson C.L. Guyre P.M. Whitin J.C. Ryan D.H. Looney R.J. Fanger M.W. Monoclonal antibodies to Fc receptors for IgG on human mononuclear phagocytes J Biol Chem 261 1986 12856 12864
54. Hogg N. The structure and function of Fc receptors Immunol Today 9 1988 185 187
55. Anderson C.L. Looney R.L. Human leukocyte Fc receptors Immunol Today 7 1986 264 265
56. Dougherry G.J. Selvendran Y. Murdoch S. Palmer D.G. Hogg N. The human mononuclear phagocyte high-affinity Fc receptor, FcRI, defined by a monoclonal antibody, 10.1 Eur J Immunol 17 1987 1453 1459
57. Staquet M.J. Dezutter-Dambuyant C. Schmitt D. Thivolet J. Adhesionmediating molecules of human Langerhans cells (abstr) J Invest Derrnatol 92 1989 522
58. Fleit H.B. Wright S.D. Unkeless J.C. Human neutrophil Fc gamma receptor distribution and structure Proc Nad Acad Sci USA 79 1982 3275 3279
59. Schulz T.F. Helmberg A. Hosp M. Petzer A. Dierich M.P. Enzymelinked immunoassay to monitor the purification of, and to screen for monoclonal antibodies against C3b receptor Complement 2 1985 219 229
60. Petzer A. Schulz T.F. Stauder R. Eigentler A. Myones B.L. Dicrich M.P. Structural and functional analysis of CR2/EBV receptor by means of monoclonal antibodies and limited tryptic digestion Immunology 63 1988 47 53
61. Sanchez-Madrid F. Krensky A.M. Ware C.F. Robbins E. Strominger J.L. Burakoff S.J. Springer T.A. Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-I, LFA-2 and LFA-3 Proc Natl Acad Sci USA 79 1982 7489 7493
62. Schulz T.F. Scharfenberger H. Lambris J.D. Rieber P. Riethmüller G. Dierich M.P. Antigenic relationship between the alpha-chain of C3, a leucocyte-surface antigen involved in the activation of phagocytic cells, and a 50,000 MW B-cell antigen Immunology 54 1985 791 800
63. Wright S.D. Rao P.E. Van Voorhis W.C. Craigmyle L.S. Iida K. Talle M.A. Westberg E.F. Goldstein G. Silverstein S.C. Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies Proc Natl Acad Sci USA 80 1983 5699 5703
64. Rothlein R. Dustin M.L. Marlin S.D. Springer T.A. A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1 J Immunol 137 1986 1270 1274
65. Inaba K. Steinman R.M. Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes J Exp Med 165 1987 1403 1412
66. Majdic O. Schnabl E. Stockinger H. Gadd S. Maurer D. Radaszkiewics T. Gaugitsch H. Lindley I. Hofer E. Knapp W: LA45, an activation-induced human lymphocyte antigen with strong homology to MHC class I molecules. In: Knapp W (cd.). Leukocyte T yping IV: White Cell Differentiation A.nt igens. Oxford University Press. Oxford, in press