A Quantitative Investigation of Hippocampal Pyramidal Cell Size, Shape, and Variability of Orientation in Schizophrenia

Archives of General Psychiatry

Volumn 46, Issue 11, 1989, Pages 1027-1032

  Christison, George W ^a   Casanova, Manuel F ^a   Weinberger, Daniel R ^a   Rawlings, Robert ^b   Kleinman, Joel E ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AUTOPSY; CLINICAL ARTICLE; HIPPOCAMPUS; HISTOLOGY; HUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SCHIZOPHRENIA;

ANTHROPOMETRY; BRAIN; CELL COUNT; COMPARATIVE STUDY; FEMALE; HIPPOCAMPUS; HUMAN; MALE; MATHEMATICAL COMPUTING; MIDDLE AGE; NEURONS; PSYCHOSURGERY; SCHIZOPHRENIA;

EID: 0024418234     PISSN: 0003990X     EISSN: 15383636     Source Type: Journal    
DOI: 10.1001/archpsyc.1989.01810110069010     Document Type: Article

References (40)

1. Pribram KH. The hippocampal system and recombinant processing. In: Isaacson RL, Pribram KH, eds. The Hippocampus. New York, NY: Plenum Publishing Corp; 1986;4:329-370.
2. Gabriel M, Sparenborg, Stolar N. An executive function of the hippocampus: pathway selection for thalamic neuronal significance code. In: Isaacson RL, Pribram KH, eds. The Hippocampus. New York, NY: Plenum Publishing Corp; 1986;4:1-40.
3. Grey JA. Précis of the neuropsychology of anxiety: an enquiry into the functions of the septo-hippocampal system. Behav Brain Sciences. 1982;5:469-534.
4. Berger TW, Berry SD, Thompson RF. Role of the hippocampus in classical conditioning of aversive and appetitive behaviors. In: Isaacson RL, Pribram KH, eds. The Hippocampus. New York, NY: Plenum Publishing Corp; 1986;4:203-240.
5. Heath RG, Walker CF. Case report: correlation of deep and surface electroencephalograms with psychosis and hallucinations in schizophrenics: a report of two cases. Biol Psychiatry. 1985;20:669-674.
6. Stevens JR. Neuropathology of schizophrenia. Arch Gen Psychiatry. 1982;39:1131-1139.
7. Nieto D, Escobar A. Major psychoses. In: Minckler J, ed. Pathology of the Nervous System. New York, NY: McGraw-Hill International Book Co; 1972;3:2654-2665.
8. Bogerts B, Meertz E, Schonfeldt-Bausch R. Basal ganglia and limbic system pathology in schizophrenia: a morphometric study of brain volume and shrinkage. Arch Gen Psychiatry. 1985;42:784-791.
9. Falkai P, Bogerts B. Cell loss in the hippocampus of schizophrenics. Eur Arch Psychiatry Neurol Sci. 1986;236:154-161.
10. Roberts GW, Ferrier IN, Lee Y, Crow TJ, Johnstone EC, Owens DGC, Bacarese-Hamilton AJ, McGregor G, O'Shaughnessey D, Polak JM, Bloom SR. Peptides, the limbic lobe and schizophrenia. Brain Res. 1983;288:199-211.
11. Farmery SM, Owen F, Poulter M, Crow TJ. Reduced high affinity cholecystokinin binding in hippocampus and frontal cortex of schizophrenic patients. Life Sci. 1985;36:473-477.
12. Jeste DV, Lohr JB. Hippocampal pathology in schizophrenia. Presented at the 25th Annual Meeting of the American College of Neuropsychopharmacology; December 9, 1986; Washington, DC.
13. Scheibel AB, Kovelman JA. Disorientation of the hippocampal pyramidal cell and its processes in the schizophrenic patient. Biol Psychiatry. 1981;16:101-102.
14. Kovelman JA, Scheibel AB. A neurohistological correlate of schizophrenia. Biol Psychiatry. 1984;19:1601-1621.
15. Altshuler LL, Conrad A, Kovelman JA, Scheibel A. Hippocampal pyramidal cell orientation in schizophrenia: a controlled neurohistologic study of the Yakovlev collection. Arch Gen Psychiatry. 1987;44:1094-1098.
16. Weinberger DR, Luchins DJ, Kleinman JE, Wyatt RJ. The hippocampus in schizophrenia: a controlled postmortem study. Presented at the 35th Annual Society of Biological Psychiatry Annual Meeting; 1980; Boston, Mass.
17. Spitzer RL, Endicott J, Robins E. Research Diagnostic Criteria for a Selected Group of Functional Disorders. 3rd ed. New York, NY: New York State Psychiatric Institute, Biometrics Research Division; 1978.
18. Lorente de No R. Studies on the structure of the cerebral cortex, II: continuation of the study of the ammonic system. J Psychol Neurol. 1934;46:113-177.
19. Armstrong E, Frost GT. Evolution of the primate subiculum. Soc Neurosci Abstr. 1988;14:527.
20. Loats HL, Whitehouse PS, Lloyd DL, Altschuler RS, Price DL. A computer image analysis system for neuron morphometry. Soc Neurosci Abstr. 1986;12:82.
21. Press WH. Numerical Recipes: The Art of Scientific Computing. New York, NY: Cambridge University Press; 1956.
22. Mardia KV. Statistics of Directional Data. Orlando, Fla: Academic Press Inc; 1972.
23. Benes FM, Paskevich PA, Davidson J, Domesick VB. The effects of haloperidol on synaptic patterns in the rat striatum. Brain Res. 1985;329:265-274.
24. Jellinger K. Neuropathologic findings after neuroleptic long-term therapy. In: Roizin L, Shiraki H, Grcebic N, eds. Neurotoxicology. New York, NY: Raven Press; 1977:25-42.
25. Greenblatt M, Solomon H. Neuropathologic lesions following lobotomy. In: Greenblatt M, Solomon H, eds. Frontal Lobes and Schizophrenia. New York, NY: Springer Publishing Co Inc; 1953:307-324.
26. Roizin L. Histopathologic observations in schizophrenia: including effects of somatic and biochemical therapies. In: Minckler J, ed. Pathology of the Nervous System. New York, NY: McGraw-Hill International Book Co; 1972:2670-2677.
27. Carpenter MB. Core Text of Neuroanatomy. 2nd ed. Baltimore, Md: Williams & Wilkins; 1978:26.
28. Shelton RC, Weinberger DR. X-ray computerized tomography studies in schizophrenia: a review and synthesis. In: Nasrallah HA, Weinberger DR, eds. Handbook of Schizophrenia, I: The Neurology of Schizophrenia. Amsterdam, the Netherlands: Elsevier Science Publishers; 1986:207-250.
29. Brown R, Colter N, Corsellis JAN, Crow TJ, Frith CD, Jagoe R, Johnstone EC, Marsh L. Postmortem evidence of structural brain changes in schizophrenia: differences in brain weight, temporal horn area, and parahippocampal gyrus compared with affective disorder. Arch Gen Psychiatry. 1986;43:36-42.
30. Swanson LW. Normal hippocampal circuitry: anatomy. Neurosciences Res Prog Bull. 1982;20:624-634.
31. Blackstad TW. On the termination of some afferents to the hippocampus and fascia dentata: an experimental study in the rat. Acta Anat. 1958;35:202-214.
32. Hjorth-Simonsen A. Projections of the lateral part of the entorhinal area of the hippocampus and fascia dentata. J Comp Neurol 1972;146:219-232.
33. Hjorth-Simonsen A, Jenne B. Origin and termination of the hippocampal perforant path in the rat studied by silver impregnation. J Comp Neurol. 1972;144:215-232.
34. Van Hoesen GW, Pardya DN. Some connections of the entorhinal (area 28) and perirhinal (area 35) cortices of the rhesus monkey, I: temporal lobe afferents. Brain Res. 1975;95:1-24.
35. Van Hoesen GW. The parahippocampal gyrus: new observations regarding its cortical connections in the monkey. TINS. 1982;5:345-350.
36. Rosene DL, Van Hoesen GW. Hippocampal efferents reach widespread areas of cerebral cortex and amygdala in the rhesus monkey. Science. 1977;198:315-317.
37. Witter MP, Groenewegen HJ. Connections of the parahippocampal cortex in the cat, III: cortical and thalamic efferents. J Comp Neurol. 1986;252:1-31.
38. Descarries L, Lemay B, Doucet G, Berger B. Regional and laminar density of the dopamine innervation in adult rat cerebral cortex. Neuroscience. 1987;21:807-824.
39. Jakob H, Beckmann H. Prenatal developmental disturbances in the limbic allocortex in schizophrenics. J Neural Transm. 1986;65:303-326.
40. Colter N, Battal S, Crow TJ, Johnstone EC, Brown R, Bruton C. White matter reduction in the parahippocampal gyrus of patients with schizophrenia. Arch Gen Psychiatry. 1987;44:1023.