Subchronic (13-week) inhalation toxicity study of formaldehyde in male rats: 8-hour intermittent versus 8-hour continuous exposures

Toxicology Letters

Volumn 47, Issue 3, 1989, Pages 287-293

  Wilmer, J W G M ^a   Woutersen, R A ^a   Appelman, L M ^a   Leeman, W R ^a   Feron, V J ^a  

^a TNO   (Netherlands)

Author keywords

Formaldehyde; Inhalation; Intermittent Versus Continuous exposure; Rats

Indexed keywords

FORMALDEHYDE;

ANIMAL EXPERIMENT; CELL GROWTH; CELL HYPERPLASIA; CHRONIC TOXICITY; CYTOTOXICITY; HISTOLOGY; HISTOPATHOLOGY; INHALATIONAL DRUG ADMINISTRATION; MALE; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL; RAT; SQUAMOUS CELL METAPLASIA;

ADMINISTRATION, INHALATION; AIR POLLUTANTS; ANIMAL; CELL SURVIVAL; COMPARATIVE STUDY; FORMALDEHYDE; MALE; NASAL MUCOSA; RATS; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T; TIME FACTORS;

EID: 0024411481     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4274(89)90147-1     Document Type: Article

References (11)

1. The effect of formaldehyde exposure on cytotoxicity and cell proliferation
2. Non-linear biological responses to formaldehyde and their implications for carcinogenic risk assessment
3. Subacute (4-week) inhalation toxicity study of formaldehyde in male rats: 8-hour continuous versus 8-hour intermittent exposures
4. Effect of single or repeated formaldehyde exposure on minute volume of B6C3F1 mice and F-344 rats
5. The colorimetric estimation of formaldehyde by means of the Hantzsch reaction
6. Cytotoxic and adaptive effects in rat nasal epithelium after 3-day and 13-week exposure to low concentrations of formaldehyde vapour
7. Subchronic (13-week) inhalation toxicity study with formaldehyde in rats
8. A 26-week inhalation toxicity study with formaldehyde in the monkey, rat and hamster
9. Induction of squamous cell carcinomas of the rat nasal cavity by inhalation exposure to formaldehyde vapor
10. Carcinogenicity of formaldehyde in rats and mice after long-term inhalation exposure
11. Epithelial damage and tumours of the nose after exposure to four different aldehydes by inhalation