Behavioral effects of MK-801 mimic deficits associated with hippocampal damage

Psychobiology

Volumn 17, Issue 2, 1989, Pages 156-164

  Robinson, George S ^a   Crooks, Geoffrey B ^a   Shinkman, Paul G ^a   Gallagher, Michela ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIZOCILPINE;

ANIMAL EXPERIMENT; BEHAVIOR; CONTROLLED STUDY; HIPPOCAMPUS; LEARNING; MALE; NONHUMAN; PSYCHOLOGICAL ASPECT; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0024405135     PISSN: 08896313     EISSN: None     Source Type: Journal    
DOI: 10.3758/BF03337831     Document Type: Article

References (32)

1. The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate
2. Amnesic effect of the novel anticonvulsant MK801
3. Long-term potentiation of hippocampal synaptic transmission affects rate of behavioral learning
4. Potentiation of odor by taste and odor aversions in rats are regulated by cholinergic activity of dorsal hippocampus
5. Flavor-illness aversions: The role of the amygdala in the acquisition of taste-potentiated odor aversions
6. Flavor-illness aversions: Potentiation of odor by taste is disrupted by application of novocaine into the amygdala
7. Long-term potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path
8. Long-term potentiation of synaptic transmission in the hippocampus: Properties and mechanisms
9. Long-term potentiation in amygdala brain slices
10. Effects of phencyclidine, SKF 10047 and related psychotomimetic agents on N-methyl-D-aspartate receptor mediated synaptic responses in rat hippocampal slices
11. Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus
12. Excitatory amino acid neurotransmission: NMDA receptors and Hebb-Type synaptic plasticity
13. Learning impairment in rats by N-methyl-D-aspartate receptor antagonists
14. Longterm potentiation in the dentate gyrus: Induction and increased glutamate release are blocked by (−)amino phosphonovalerate
15. Altered synaptic transmission in dentate gyrus of rats reared in complex environments: Evidence from hippocampal slices maintained in vitro
16. Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors
17. Role of temporal order and odor intensity in taste-potentiated odor aversions
18. Flavor-illness aversions: Potentiation of odor by taste in rats with gustatory neocortex ablations
19. MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys
20. A comparison of the contributions of frontal and parietal association cortex to spatial localization in rats
21. Projections from the amygdaloid complex and adjacent olfactory structures to the entorhinal cortex and to the subiculum in the rat and cat
22. A within-event analysis of taste-potentiated odor and contextual aversions
23. Disruption of neophobia, conditioned odor aversion and conditioned taste aversion in rats with hippocampal lesions
24. 3H-glutamate binding sites in rat brain as determined by quantitative autoradiography
25. 3H-L-glutamate binding sites
26. Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
27. Place navigation impaired in rats with hippocampal lesions
28. Flavor-illness aversions: Potentiation of odor by taste in rats
29. Enhancement of hippocampal field potentials in rats exposed to a novel complex environment
30. Elimination of long-term potentiation in the hippocampus by phencyclidine and ketamine
31. Both competitive and non-competitive antagonists of N-methyl-D-aspartic acid disrupt brightness discrimination in rats
32. Decortication abolishes place but not cue learning in rats